Swiss National Iodine Survey 2020

This study will assess iodine status in school aged children and pregnant women is Switzerland. In addition, thyroid status and omega-3 index will be assessed in pregnant women.

Study Overview

• Status: Completed
• Conditions: Healthy
• Intervention / Treatment: Other: There is no intervention. It is an observational study.

• Study Type: Observational
• Enrollment (Actual): 875

Contacts and Locations

Study Locations

• Switzerland
  • Zurich, Switzerland, 8092
    • Human Nutrition Laboratory, ETH Zurich

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 6 years to 44 years (Child, Adult)
• Accepts Healthy Volunteers: Yes

• Sampling Method: Probability Sample

Study Population

Both groups: nationally representative sample selected through schools (children) and gynecologists (women).

School aged children: aged between 6 and 12 years Pregnant women: aged between 18 and 44 years, pregnant

Description

Inclusion Criteria:

• Healthy
• for pregnant women: confirmed pregnancy
• living in Switzerland for min 1 year

Exclusion Criteria:

• no history of major medical illness
• no iodine containing contrast agents or medication in the past 6 months

Study Plan

How is the study designed?

Design Details

• Observational Models: Cohort
• Time Perspectives: Cross-Sectional

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Pregnant women	Other: There is no intervention. It is an observational study.; There is not intervention
School aged children	Other: There is no intervention. It is an observational study.; There is not intervention

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Urinary iodine concentration	urinary iodine concentration in spot urine samples	Baseline

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Urinary creatinine concentration	Urinary creatinine concentration in spot urine samples	Baseline
Urinary sodium concentration	Urinary sodium concentration in spot urine samples	Baseline
Urinary fluoride concentration	Urinary fluoride concentration in spot urine samples	Baseline
Thyroid stimulating hormone	TSH from dried blood spots	Baseline
T3	T3 from dried blood spots	Baseline
T4	T4 from dried blood spots	Baseline
Omega 3 index	Omega 3 index from dried blood spots	Baseline

Other Outcome Measures

Outcome Measure	Measure Description	Time Frame
Height		Baseline
Weight		Baseline
Omega 3 intake	Assessment of omega 3 intake using a food frequency questionnaire	Baseline
Depressive symptoms	Assessment of depressive symptoms using the Edinburgh Postnatal Depression Scale (EPDS).	Baseline

Collaborators and Investigators

• Sponsor: Isabelle Herter-Aeberli
• Collaborators: University Children's Hospital, Zurich; Department of Epidemiology and Health Services, Unisanté, Lausanne

Study record dates

Study Major Dates

• Study Start (Actual): October 1, 2020
• Primary Completion (Actual): August 31, 2022
• Study Completion (Actual): July 30, 2023

Study Registration Dates

• First Submitted: August 12, 2020
• First Submitted That Met QC Criteria: August 19, 2020
• First Posted (Actual): August 24, 2020

Study Record Updates

• Last Update Posted (Actual): November 22, 2023
• Last Update Submitted That Met QC Criteria: November 21, 2023
• Last Verified: November 1, 2023

More Information

Terms related to this study

• Other Study ID Numbers: 2020-00192

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No