Great Posture, Great Health (GPGH)

Great Posture, Great Health - A Community-Based Postural Intervention for Improving Holistic Health

The purpose of this study is to examine the effect of a posture intervention on specific areas of daily function and health: physical, psychological, cognitive, social, and environmental characteristics.

Study Overview

• Status: Completed
• Conditions: Healthy
• Intervention / Treatment: Behavioral: Postural Intervention Program

Detailed Description

This project promotes community health through postural movement to demonstrate strong physical and mental health benefits. Specifically, Great Posture, Great Health will address two of the top five priorities of general health concerns: 1) obesity and 2) mental health. First, obesity is on the rise although more individuals are meeting or exceeding the current federal physical activity guidelines based on the data provided by the US Department of Health and Human Services (2020). Obesity is a common problem in adults with all socioeconomic status and all races, except Asians. In fact, Asians have low rates of heart disease, asthma, cancer, and a longer life expectancy than other races, potentially due to health behaviors, environment, and stress coping strategies (Acciai et al., 2015). Therefore, we should not overlook the importance of stress coping strategies practiced in Asian countries on obesity. It is becoming more evident that chronic stress (such as elevated cortisol levels) and steroid-based medications are strongly associated with obesity and chronic diseases. It is critical to develop and validate community health strategies to address both priorities. Great Posture, Great Health will introduce one of the most common mind-body postural exercises practiced in Asian countries to a large and diverse population.

• Study Type: Interventional
• Enrollment (Actual): 114
• Phase: Not Applicable

Contacts and Locations

Study Locations

• United States
  • Minnesota
    • Rochester, Minnesota, United States, 55905
      • Mayo Clinic in Rochester

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 12 years and older (Child, Adult, Older Adult)
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• Participants must be physically capable (defined as easy to moderate physical activities daily at least 60 minutes).
• Participants also must have a normal (18.5-24.9kg/m2) or overweight BMI (25-29.9kg/m2).
• Participants must be able to speak, listen, read, and understand sentences written in English.

Exclusion Criteria:

• More than two risk factors for coronary artery disease (high blood pressure, high blood cholesterol level (LDL), family history (a close relative with heart disease), diabetes mellitus, chronic kidney disease
• History of falls, osteoporosis, osteoarthritis, or orthopedic or neurological conditions (i.e., stroke)
• Medications that cause dizziness or slow movement
• Smoke
• Body mass to height squared ratio greater than 30kg/m2 or less than 18.4kg/m2, blood pressure greater than 140/90 mmHg, or a history of heart conditions.
• Individuals with progressive cognitive, neurologic disorders, cancer treatment, chronic heart failure, or unstable medical conditions

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Supportive Care
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Intervention Group; Subjects will participate in a 15 minute postural intervention program 2-3 times per week	Behavioral: Postural Intervention Program; Dynamic warmup program designed to target several areas of physical and mental wellbeing.
No Intervention: Control Group; Subjects will NOT participate in any postural intervention.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Thigh Strength	Isometric measurement (Newtons) of quadriceps and hamstrings musculature	12-week differences (Pre- and Post-intervention measures)
Posture	Posture will be measured via the Posture Screen Mobile app. Displacement (mm)	12-week differences (Pre- and Post-intervention measures)
Bone density	Bone densiometry will be measured via quantitative ultrasound (Achilles EXPII, GE). T-score.	12-week differences (Pre- and Post-intervention measures)

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
PROMIS - Physical Activity	Patient Reported Outcomes from a computerized adaptive test (T-score; normative score is 1.0; higher score equates to a better outcome)	12-week differences (Pre- and Post-intervention measures)
PROMIS - Physical Function	Patient Reported Outcomes from a computerized adaptive test (T-score; normative score is 1.0; higher score equates to a better outcome)	12-week differences (Pre- and Post-intervention measures)
PROMIS - Pain Interference	Patient Reported Outcomes from a computerized adaptive test (T-score; normative score is 1.0; higher score equates to a better outcome)	12-week differences (Pre- and Post-intervention measures)
Mindful Attention Awareness Scale (MAAS)	Patient Reported Outcomes (Mean score range: 1-6; higher score equates to increased mindfulness)	12-week differences (Pre- and Post-intervention measures)
Perceived Stress Scale (PSS-10)	Patient Reported Outcomes (Score range: 0-40; higher score equates to increased stress)	12-week differences (Pre- and Post-intervention measures)
Generalized Anxiety Disorder (GAD7)	Patient Reported Outcomes (Score range: 0-21; higher score equates to increased anxiety)	12-week differences (Pre- and Post-intervention measures)
Patient Health Questionnaire Depression Scale (PHQ)	Patient Reported Outcomes (Score range: 0-27; score of 10 or greater is considered major depression, 20 or more is severe major depression.)	12-week differences (Pre- and Post-intervention measures)
Sex	Demographic co-variate. (M/F)	Through study completion, an average of 1 year
Age	Demographic co-variate (years)	Through study completion, an average of 1 year
BMI	Demographic co-variate (BMI index; kg/m^2)	12-week differences (Pre- and Post-intervention measures)

Collaborators and Investigators

• Sponsor: Mayo Clinic
• Investigators: Principal Investigator: Benjamin Holmes, DC, PhD, Mayo Clinic

Publications and helpful links

Helpful Links

• Mayo Clinic Clinical Trials

Study record dates

Study Major Dates

• Study Start (Actual): November 19, 2020
• Primary Completion (Actual): March 19, 2024
• Study Completion (Actual): March 19, 2024

Study Registration Dates

• First Submitted: October 28, 2020
• First Submitted That Met QC Criteria: November 13, 2020
• First Posted (Actual): November 16, 2020

Study Record Updates

• Last Update Posted (Actual): April 11, 2024
• Last Update Submitted That Met QC Criteria: April 9, 2024
• Last Verified: April 1, 2024

More Information

Terms related to this study

• Keywords: exercise; community; posture
• Other Study ID Numbers: 20-004586

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No