New Ways of Doing Magnetic Resonance Imaging in Children and Adults

New Image Techniques for Magnetic Resonance Imaging in Children and Adults

This study is being done to see how we can prevent problems caused by movement during the MRI scan. Different ways of doing the scan (techniques) will be tested to see if they are practical and can prevent problems related to motion. For example, changes in the timing of the magnetic field and the radio waves will be examined, and at changes in the way a computer is used to process the images. The new techniques will be compared with the techniques that are usually used.

Study Overview

• Status: Active, not recruiting
• Conditions: Pediatric Disorder; Adult Disease
• Intervention / Treatment: Diagnostic test: MRI

• Study Type: Observational
• Enrollment (Actual): 21

Contacts and Locations

Study Locations

• United States
  • New York
    • New York, New York, United States, 10065
      • Memorial Sloan Kettering Cancer Center

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Probability Sample

Study Population

Potential research subjects will be identified by a member of the patient's treatment team, the protocol investigator, or research team at Memorial Sloan-Kettering Cancer Center (MSK). With consultation of the clinical team, the investigator or a consenting professional from the research team will go to the treating physician's clinic to discuss the study and consent the patient in person.

Description

Inclusion Criteria:

• Patients of any age, including males and females, who are being treated in the Department of Pediatrics and are already scheduled to undergo MRI

Exclusion Criteria:

• Anyone who would normally be excluded from undergoing an MRI examination as per Memorial Hospital for Cancer and Allied Diseases Screening Questionnaire for MRI (Appendix A). Subjects with pacemakers or aneurysm clips that are MRI conditional or MRI compatible may enroll in the study if the study is clinically indicated.
• Female patients who are pregnant
• Patients who are unable to comply or complete the MRI exam due to claustrophobia or high levels of anxiety
• Patients at higher risk due to age, frailty, or the emergent nature of their condition
• Patients who are undergoing MRI only of the head, neck or spine

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Study Participants; Patients of any age, including males and females, who are being treated in the Department of Pediatrics and are already scheduled to undergo MRI	Diagnostic test: MRI; Briefly, new MRI sequences will be used on a patient who is undergoing a scheduled, clinically necessary MRI exam. Any new research sequence will be scanned in addition to the clinically required sequences and will not interfere with the clinical scan other than requiring five to ten minutes of additional "table time". There will be no invasive measures under this protocol.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Compare Image Quality	To assess the new MRI sequences or MRI analysis methods and compare their image quality to current clinical ones. Specifically, we aim to compare the routine sequences with the experimental sequences.	Day of MRI

Collaborators and Investigators

• Sponsor: Memorial Sloan Kettering Cancer Center
• Investigators: Principal Investigator: Gerald Behr, MD, Memorial Sloan Kettering Cancer Center

Publications and helpful links

Helpful Links

• Memorial Sloan Kettering Cancer Center

Study record dates

Study Major Dates

• Study Start (Actual): November 18, 2020
• Primary Completion (Estimated): November 18, 2026
• Study Completion (Estimated): November 18, 2026

Study Registration Dates

• First Submitted: November 19, 2020
• First Submitted That Met QC Criteria: November 19, 2020
• First Posted (Actual): November 24, 2020

Study Record Updates

• Last Update Posted (Estimated): September 3, 2025
• Last Update Submitted That Met QC Criteria: August 26, 2025
• Last Verified: August 1, 2025

More Information

Terms related to this study

• Keywords: MRI; Magnetic Resonance Imaging; Memorial Sloan Kettering Cancer Center; 20-482
• Additional Relevant MeSH Terms: Pathologic Processes; Pathological Conditions, Signs and Symptoms; Disease
• Other Study ID Numbers: 20-482

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: YES
• IPD Plan Description: Memorial Sloan Kettering Cancer Center supports the international committee of medical journal editors (ICMJE) and the ethical obligation of responsible sharing of data from clinical trials. The protocol summary, a statistical summary, and informed consent form will be made available on clinicaltrials.gov when required as a condition of Federal awards, other agreements supporting the research and/or as otherwise required. Requests for deidentified individual participant data can be made beginning 12 months after publication and for up to 36 months post publication. Deidentified individual participant data reported in the manuscript will be shared under the terms of a Data Use Agreement and may only be used for approved proposals. Requests may be made to: crdatashare@mskcc.org.

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No