Validity and Reliability of Commercially Available Metabolic Carts

The validity (by alcohol burning and gas infusions) and reliability (day-to-day variability in healthy subjects) of six metabolic carts will be compared.

Study Overview

• Status: Completed
• Conditions: Metabolism and Nutrition Disorder
• Intervention / Treatment: Device: Assessment of resting energy expenditure

• Study Type: Observational
• Enrollment (Actual): 20

Contacts and Locations

Study Locations

• United States
  • Louisiana
    • Baton Rouge, Louisiana, United States, 70809
      • Pennington Biomedical Research Center

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 65 years (ADULT, OLDER_ADULT)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Healthy adults

Description

Inclusion Criteria:

• Healthy male or female.
• Age 18-65 y.
• BMI between 18.5 kg/m2 and 40 kg/m2 (inclusive).
• Are willing to fast and not consume non-caloric stimulant for 10h before the assessments, and during the stay in the center.
• Are willing to avoid moderate or vigorous physical activity during 24h before the visits.

Exclusion Criteria:

• Smoking or use of tobacco products within the last 3 months
• Diagnosed with diabetes.
• Previous bariatric surgery (or other surgeries) for obesity or weight loss.
• Use of medications affecting metabolism or sleep.
• History of neurological disease.
• History of cardiovascular disease, including hypertension, or other chronic diseases.
• Pregnant, planning to become pregnant, or breastfeeding
• Claustrophobia impeding to stay calm under a plastic canopy.

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Resting metabolic rate	Indirect calorimetry	30 minutes

Collaborators and Investigators

• Sponsor: Pennington Biomedical Research Center

Study record dates

Study Major Dates

• Study Start (ACTUAL): July 22, 2021
• Primary Completion (ACTUAL): February 7, 2022
• Study Completion (ACTUAL): February 7, 2022

Study Registration Dates

• First Submitted: July 29, 2021
• First Submitted That Met QC Criteria: July 29, 2021
• First Posted (ACTUAL): August 6, 2021

Study Record Updates

• Last Update Posted (ACTUAL): June 15, 2022
• Last Update Submitted That Met QC Criteria: June 12, 2022
• Last Verified: June 1, 2022

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Nutrition Disorders
• Other Study ID Numbers: PBRC2020-036

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: Yes