Efficacy of Lung Ultrasound in Monitoring Fluid Resuscitation in Chest Trauma Patients

Efficacy of Lung Ultrasound in Monitoring Fluid Resuscitation in Trauma Patients

Efficacy of Lung ultrasound in monitoring fluid resuscitation in chest trauma patients with lung contusions

Study Overview

• Status: Completed
• Conditions: Lung Injury; Chest Trauma; Fluid Overload Pulmonary Edema; Contusions Pulmonary
• Intervention / Treatment: Other: Chest examination with Ultrasound device

Detailed Description

Trauma is a public health problem, associated to high morbidity and mortality, In Egypt the mortality from road traffic crashes is about 12000 victims per year.

• Chest trauma represents from 10% to 15% of the total number of traumas worldwide.

According to ATLS protocol , early diagnosis and management of Chest trauma are essential. *Pulmonary contusion is found in 30-75% of cases of chest injury.

• point of care Ultrasound (POCUS) is Now a corner stone in Emergency management it can predict lung contusions within the first 72 hours after trauma.
• Recently, LUS Play a major role in assessment of the volume status in Trauma patients.
• B-lines score (BLS) has been validated as a lung ultrasound quantification of pulmonary congestion.The sum of all B-lines yields a score, B-lines score (BLS), which assess the degree of lung contusion. So that LUS may provide a valuable safety threshold to conduct fluid therapy.

• Study Type: Observational
• Enrollment (Actual): 100

Contacts and Locations

Study Locations

• Egypt
  • Assiut, Egypt
    • Faculty of Medicine Assiut University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: N/A

• Sampling Method: Non-Probability Sample

Study Population

This is an observational study that will be conducted on patients admitted with chest trauma in Assuit or Alexandria Main University Hospitals after obtaining their or their next of kin consent to participate in the study without affecting their course of treatment according to permission obtained from ethical committee of faculty of medicine in Assiut and Alexandria universities.

Description

Inclusion Criteria:

• Age > 18 years.
• chest trauma patients either with or without other injuries.
• Any patient with either blunt or penetrating chest trauma.

Exclusion Criteria:

• - Patients in cardiac arrest.
• Patient refusal to participate
• Pregnant females.

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Number of patients with lung contusion	Pulmonary edema will be detected by B_lines trauma patients with lung contusions	Upto 24 hours after trauma

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Clinical correlation between Type & volume of Fluid & occurance of pulmonary edema. Correlation between severity of pulmonary lung contusion & The final disposition of the patients whatever (OR _another department _death….. etc) upto 24hr.	Follow up on degree of contusions after fluid resuscitation	For first 24 hours after trauma

Collaborators and Investigators

• Sponsor: Assiut University

Publications and helpful links

General Publications

• Ullman EA, Donley LP, Brady WJ. Pulmonary trauma emergency department evaluation and management. Emerg Med Clin North Am. 2003 May;21(2):291-313. doi: 10.1016/s0733-8627(03)00016-6.
• Miller DL, Mansour KA. Blunt traumatic lung injuries. Thorac Surg Clin. 2007 Feb;17(1):57-61, vi. doi: 10.1016/j.thorsurg.2007.03.017.
• Cohn SM. Pulmonary contusion: review of the clinical entity. J Trauma. 1997 May;42(5):973-9. doi: 10.1097/00005373-199705000-00033.

Study record dates

Study Major Dates

• Study Start (Actual): July 1, 2021
• Primary Completion (Actual): June 1, 2022
• Study Completion (Actual): June 1, 2023

Study Registration Dates

• First Submitted: June 2, 2021
• First Submitted That Met QC Criteria: September 22, 2021
• First Posted (Actual): September 23, 2021

Study Record Updates

• Last Update Posted (Actual): July 30, 2024
• Last Update Submitted That Met QC Criteria: July 29, 2024
• Last Verified: July 1, 2021

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Respiratory Tract Diseases; Lung Diseases; Wounds, Nonpenetrating; Wounds and Injuries; Lung Injury; Thoracic Injuries; Pulmonary Edema; Contusions
• Other Study ID Numbers: Chest US in lung contusion

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No