COVID-19 Vaccine Hesitancy Among Nurses

The purpose of this study is to investigate the correlation of intention to receive COVID-19 vaccine, recommendation behavior, and 5C psychological antecedents among Nurses. The results can be used to assist suggestions in the health education provided by nurses on the topic of COVID-19 pneumonia and its vaccination. The purpose of the study is also wants to build a basis for future research and public support in vaccine decision-making, as well as to enhance the promotion of vaccine policy and enhance the resilience of the whole population during the pandemic ear.

Study Overview

• Status: Completed
• Conditions: COVID-19; Vaccine Hesitancy; Vaccination; Nurses
• Intervention / Treatment: Other: Questionnaires

Detailed Description

A cross-sectional study based on convenience samples. The investigators recruit nurses and the general public to respond to structured self-filling electronic questionnaires by using an electronic data collection system. The questionnaires include demographic data and vaccine hesitancy questions in a total of 35 items. Convenience sampling was applied to estimate the sample size according to the number of nurses in each county. It is planned to collect a total of 4258 responses by the end of the study. The study instrument is the 5C psychological antecedents of vaccination, which includes Confidence, Complacency, Constraints, Calculation, and Collective Responsibility.

• Study Type: Observational
• Enrollment (Actual): 4258

Contacts and Locations

Study Locations

• Taiwan
  • Taipei, Taiwan
    • Department of Nursing, National Taiwan University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 20 years to 80 years (Adult, Older Adult)
• Accepts Healthy Volunteers: Yes

• Sampling Method: Non-Probability Sample

Study Population

[Nurses] Adult (≥ 20 and ≤80 years) male and female participants with verification of registered nurse license.

[General publics] Adult (≥ 20 and ≤80 years) male and female participants with reading abilities above the intermediate level.

Description

[Nurses]

Inclusion Criteria:

• Male and female participants must be ≥ 20 years at the time of informed consent.
• Male and female participants have verification of registered nurse license.

Exclusion Criteria:

• Male and female participants be>80 years at the time of informed consent.

[General publics]

Inclusion Criteria:

• Male and female participants must be ≥ 20 years at the time of informed consent.
• Male and female participants have reading abilities above the intermediate level.

Exclusion Criteria:

• Male and female participants be>80 years at the time of informed consent.

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Nurses; Adult (≥ 20 and ≤80 years) male and female participants with verification of registered nurse license.	Other: Questionnaires; The questionnaires include demographic data and vaccine hesitancy questions in a total of 35 items.
General publics; Adult (≥ 20 and ≤80 years) male and female participants with reading abilities above the intermediate level.	Other: Questionnaires; The questionnaires include demographic data and vaccine hesitancy questions in a total of 35 items.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
The correlation of intention to receive COVID-19 vaccine and 5C psychological antecedents (5C scale) among nurses and general publics.	The 5C scale measures the psychological antecedents of vaccination, using 15 item tools including 5 domains (confidence, complacency, constraints, calculation, and collective responsibility). Each domain was assessed by 3 rating items on a 7-point scale (1=strongly disagree; 7=strongly agree). The mean scores of items under each domain were computed, with a higher average score indicating stronger agreement of the corresponding domain.	The questionnaire length around 10 minutes.

Collaborators and Investigators

• Sponsor: National Taiwan University Hospital
• Investigators: Principal Investigator: Jung-Chen Chang, Ph.D, Department of Nursing, National Taiwan University

Study record dates

Study Major Dates

• Study Start (Actual): February 22, 2022
• Primary Completion (Actual): May 19, 2022
• Study Completion (Actual): May 19, 2022

Study Registration Dates

• First Submitted: January 24, 2022
• First Submitted That Met QC Criteria: January 24, 2022
• First Posted (Actual): January 28, 2022

Study Record Updates

• Last Update Posted (Actual): July 9, 2024
• Last Update Submitted That Met QC Criteria: July 7, 2024
• Last Verified: May 1, 2023

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Virus Diseases; Infections; Respiratory Tract Infections; Respiratory Tract Diseases; Pneumonia, Viral; Pneumonia; Lung Diseases; COVID-19
• Other Study ID Numbers: 202106114RINA

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No