The Effect of Whole Body Vibration After ACLR

The Effect of Whole Body Vibration on Dynamic Knee Stability in Patients After Anterior Cruciate Ligament Reconstruction

This is a randomised clinical trial to detect the effect of an 8-week whole body vibration training on muscle function and dynamic knee function during single leg squat and single leg hop in patients after anterior cruciate ligament reconstruction

Study Overview

• Status: Recruiting
• Conditions: ACL Injury
• Intervention / Treatment: Other: whole body vibration; Other: Conventional exercise training

Detailed Description

In Hong Kong, over 3000 cases of ACL reconstruction are operated annually to restore knee stability. Despite recovery of knee passive laxity and muscle strength, dynamic knee stability is often not restored. The whole body vibration has been found to improve muscle strength, proprioception and balance after ACL reconstruction. This project will investigate the effect of whole body vibration on muscle elasticity, muscle coordination and landing knee biomechanics. It may provide useful evidence to the application of whole body vibration in improving dynamic knee stability, which will lead to a significant improvement in healthcare management for ACL patients . The current study serves to provide a clinical guideline for post-ACL reconstruction rehabilitation.

• Study Type: Interventional
• Enrollment (Estimated): 50
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Xin He, PhD; Phone Number: 68102694; Email: xinhe@cuhk.edu.hk

Study Locations

• Hong Kong
  • Hong Kong, Hong Kong
    • Recruiting
    • The Chinese University of Hong Kong
    • Contact: Michael Tim-Yun Ong, Master

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 50 years (Adult)
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

1. Aged 18-50;
2. Physically active before injury with Tegner score more than 6 (recreational/professional sport level);
3. Scheduled for ACLR because of sport injury;
4. Be able to walk with a pair of elbow crutches independently at 1 month after ACLR.

Exclusion Criteria:

1. Concomitant posterior cruciate ligament or lateral collateral ligament injury in the same knee;
2. Injury to the contralateral side;
3. Medical problems that are contradictory to WBV;
4. Prior experience of WBV to avoid any training or memory effect;
5. Women with pregnancy.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Supportive Care
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Vibration group; Participants in Vibration group will receive an 8-week whole body vibration training in addition to conventional exercise training.	Other: whole body vibration; The whole body vibration is used when vibrations (mechanical oscillations) of a certain frequency are transferred to the human body. Humans are exposed to vibration through a contact surface that is in a mechanical vibrating state. It has been considered as an alternative and safe method for neuromuscular training and may be incorporated into current neuromuscular rehabilitation programs so as to enhance muscle recovery; Other: Conventional exercise training; A set of conventional exercises designed for ACL rehabilitation
Active Comparator: Control group; Participants in Vibration group will only receive conventional exercise training.	Other: Conventional exercise training; A set of conventional exercises designed for ACL rehabilitation

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
knee flexion angle	Peak value of knee flexion will be assessed by the skin marker-based motion analysis system (Vicon MX, Oxford, UK) during single leg squat and single leg hop landing.	immediately after intervention, three month after intervention
knee valgus angle	Peak value of knee valgus will be assessed by the skin marker-based motion analysis system (Vicon MX, Oxford, UK) during single leg squat and single leg hop landing.	immediately after intervention, three month after intervention
knee internal rotation angle	Peak value of knee internal rotation will be assessed by the skin marker-based motion analysis system (Vicon MX, Oxford, UK) during single leg squat and single leg hop landing.	immediately after intervention, three month after intervention
Vertical ground reaction force	Peak vertical ground reaction force will be evaluated by a synchronized force plate during single leg hop landing.	immediately after intervention, three month after intervention
Knee valgus torque	Peak knee valgus torque will be evaluated by a synchronized force plate during single leg hop landing.	immediately after intervention, three month after intervention
Knee extension torque	Peak knee extension torque will be evaluated by a synchronized force plate during single leg hop landing.	immediately after intervention, three month after intervention

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
muscle strength	Isometric muscle strength of quadriceps and hamstring will be tested using an hand-held dynamometer. The isokinetic muscle strength of quadriceps and hamstring will be tested at 60°/s and 180°/s by the isokinetic dynamometer	immediately after intervention, three month after intervention
muscle elasticity	Shear elastic modulus of vastus medialis, vastus lateralis, semimembranosus and biceps femoris will be assessed by shear wave elastography ultrasound.	immediately after intervention, three month after intervention
muscle activation	Muscle activity level of vastus lateralis, vastus medialis, biceps femoris and semitendinosus will be assessed by electromyography	immediately after intervention, three month after intervention

Collaborators and Investigators

• Sponsor: Chinese University of Hong Kong
• Investigators: Principal Investigator: Xin He, PhD, Chinese University of Hong Kong

Study record dates

Study Major Dates

• Study Start (Actual): January 1, 2021
• Primary Completion (Estimated): January 1, 2025
• Study Completion (Estimated): December 1, 2025

Study Registration Dates

• First Submitted: January 27, 2022
• First Submitted That Met QC Criteria: February 17, 2022
• First Posted (Actual): February 24, 2022

Study Record Updates

• Last Update Posted (Actual): August 30, 2023
• Last Update Submitted That Met QC Criteria: August 29, 2023
• Last Verified: August 1, 2023

More Information

Terms related to this study

• Keywords: ACL; whole body vibration; dynamic knee stability
• Additional Relevant MeSH Terms: Wounds and Injuries; Leg Injuries; Knee Injuries; Anterior Cruciate Ligament Injuries
• Other Study ID Numbers: 2019.432

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No