Novel Equation for Estimating Intraperitoneal Pressure

Novel Equation for Estimating Intraperitoneal Pressure in Patients on Peritoneal Dialysis Patients

Intraperitoneal Pressure is associated with the complications of increased intra-abdominal pressure in peritoneal dialysis patients. Due to the complicated operations, routine measurement of hydrostatic intraperitoneal pressure is not used routinely in adult peritoneal dialysis patients. There ars some limitions in equations from previous studies, such as the sample size was small , and the study population was limited. In the study, we aim to develop and validate an equation for estimating intraperitoneal pressure in peritoneal patients.

Study Overview

• Status: Completed
• Conditions: Peritoneal Dialysis; Equation; Intraperitoneal Pressure

• Study Type: Observational
• Enrollment (Actual): 200

Contacts and Locations

Study Locations

• China
  • Beijing
    • Beijing, Beijing, China, 100034
      • Jie Dong

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 80 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

All peritoneal dialysis patients meet the inclusion and exclusion criteria in a single center

Description

Inclusion Criteria:

• Peritoneal dialysis patients
• Dialysis length >1 month
• Aged 18-80 years
• Injection volume of peritoneal dialysis solution>1500ml

Exclusion Criteria:

• Acute complications （ peritonities, cardiovascular and cerebrovascular diseases) to hospitalization 1 month prior to the study
• History of abdominal surgery and trauma 1 month prior to the study
• Previous history of hernia, leakage, or thoracoabdominal fistula
• Can't come for a follow-up visit

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Novel equation development	Developed equation for estimating intraperitoneal pressure in peritoneal dialysis patients	July 17, 2021 to September 30, 2021
Novel equation validation	Validate the novel equation with intraperitoneal pressure obtained by Durand method	October 1,2021 to October 31,2021

Collaborators and Investigators

• Sponsor: Peking University First Hospital

Study record dates

Study Major Dates

• Study Start (Actual): July 17, 2021
• Primary Completion (Actual): October 31, 2021
• Study Completion (Actual): October 31, 2021

Study Registration Dates

• First Submitted: March 29, 2022
• First Submitted That Met QC Criteria: March 29, 2022
• First Posted (Actual): April 6, 2022

Study Record Updates

• Last Update Posted (Actual): April 6, 2022
• Last Update Submitted That Met QC Criteria: March 29, 2022
• Last Verified: March 1, 2022

More Information

Terms related to this study

• Other Study ID Numbers: IPP equation

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No