Comparison Between the Effect of Infiltration Between the Popliteal Artery and Capsule of the Knee Block Versus Selective Tibial Nerve Block for Postoperative Analgesia in Patient Undergoing Total Knee Arthroplasty. A Prospective Randomized Study

Comparison Between i Pack Block and Post Tibial Nerve Block

Comparison Between the Effect of Infiltration Between the Popliteal Artery and Capsule of the Knee Block Versus Selective Tibial Nerve Block for Postoperative Analgesia in Patient Undergoing Total Knee Arthroplasty.

Study Overview

• Status: Completed
• Conditions: Postoperative Analgesia
• Intervention / Treatment: Procedure: Adductor canal block with Ipack block or selective tibial nerve block

• Study Type: Interventional
• Enrollment (Actual): 70
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Egypt
  • Tanta, Egypt
    • Tanta University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 40 years to 80 years (ADULT, OLDER_ADULT)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• Patients with osteoarthritis scheduled for a primary either partial or total knee arthroplasty • Patients aged 40-80 years with a body mass index of 18-36 kg/ m2 and an American Society of Anesthesiologists functional status of I-III Planned use of regional anesthesia

Exclusion Criteria:

• • Patients younger than 40 years old and older than 80years.

  • Hepatic or renal insufficiency.
  • Patients undergoing general anesthesia.
  • Allergy or intolerance to one of the study medications.
  • BMI > 36
  • Diabetes
  • ASA of IV
  • Chronic opioid use (taking opioids for longer than 3 months, or daily oral morphine equivalent of >5mg/day for one month)

Study Plan

How is the study designed?

Design Details

• Primary Purpose: SUPPORTIVE_CARE
• Allocation: RANDOMIZED
• Interventional Model: PARALLEL
• Masking: SINGLE

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
ACTIVE_COMPARATOR: Adductor canal block with Ipack block	Procedure: Adductor canal block with Ipack block or selective tibial nerve block; Ultrasound guided
ACTIVE_COMPARATOR: Adductor canal block with selective tibial nerve block	Procedure: Adductor canal block with Ipack block or selective tibial nerve block; Ultrasound guided

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Total morphine consumption	24 hours	24 hours post operative

Collaborators and Investigators

• Sponsor: Tanta University
• Investigators: Principal Investigator: Marwa Abogabal, MD, Tanta University; Principal Investigator: Wafaa Abdelwahed, MD, Tanta University; Principal Investigator: Wafaa Abdelsalam, MD, Kafr elsheikh university; Principal Investigator: Shaimaa Zahra, Tanta University

Study record dates

Study Major Dates

• Study Start (ACTUAL): January 1, 2022
• Primary Completion (ACTUAL): June 15, 2022
• Study Completion (ACTUAL): June 30, 2022

Study Registration Dates

• First Submitted: July 22, 2022
• First Submitted That Met QC Criteria: July 22, 2022
• First Posted (ACTUAL): July 26, 2022

Study Record Updates

• Last Update Posted (ACTUAL): July 26, 2022
• Last Update Submitted That Met QC Criteria: July 22, 2022
• Last Verified: December 1, 2021

More Information

Terms related to this study

• Other Study ID Numbers: 35151/12/21

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No