Racial Differences in Yoga-Induced Responses

Racial Differences in Yoga-Induced Cardiovascular and Immune Responses

The purpose of this study is to 1) determine whether racial differences are evident in resting arterial stiffness and ambulatory blood pressure between African Americans and Caucasians 2) compare heart rate, blood pressure and cytokine production responses to exercise (yoga) between African Americans and Caucasians; 3) compare isokinetic muscular strength between racial groups; and 4) determine if correlations exist between these measures.

Study Overview

• Status: Withdrawn
• Conditions: Cardiovascular and Immune Responses to Yoga
• Intervention / Treatment: Behavioral: Vinyasa yoga session

• Study Type: Interventional
• Phase: Not Applicable

Contacts and Locations

Study Locations

• United States
  • Texas
    • San Marcos, Texas, United States, 78666
      • Stacy Hunter

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 14 years to 35 years (Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: Male

Description

Inclusion Criteria:

• Men between the ages of 18 and 39 (25 African American and 25 Caucasian) that are not professional or collegiate athletes
• Must exercise at least 3 days per week and have no more than 1 month of yoga practice.

Exclusion Criteria:

• Having stage 2 hypertension (>130 mmHg for systolic / >90 mmHg for diastolic) or higher or having taken BP medications within the 3 months prior to testing
• Infection within the previous 4 weeks
• Known renal disease
• Prior myocardial infarction
• Known coronary artery disease
• Personal history of stroke
• Heart failure
• Cardiac arrhythmias
• Chronic obstructive pulmonary disease
• Recent chest pain or dyspnea
• Orthopedic limitations that preclude the execution of yoga postures
• Current insulin dependence
• Chronic inflammatory conditions
• Blindness or deafness as participants will need to follow a yoga DVD in order to complete the session
• Having practiced yoga for more than 1 month
• Having parents of mixed racial backgrounds (i.e. both parents must be Caucasian or African American)
• Not being African American or Caucasian
• Being a professional or collegiate athlete
• Being insulin-dependent

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Basic Science
• Allocation: N/A
• Interventional Model: Single Group Assignment
• Masking: None (Open Label)

Number of Arms

1

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: 1-hour vinyasa yoga session; Participants will complete a 1-hour vinyasa yoga DVD.	Behavioral: Vinyasa yoga session; One hour of vinyasa yoga will be completed.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Arterial stiffness	Cardio-ankle vascular index	Once at baseline
Ambulatory blood pressure	24 hours of ambulatory blood pressure monitoring	Once at baseline
Isokinetic strength	Isokinetic leg extension and flexion strength assessments at 60,120,210,300, and 400 degrees per second	Once at baseline
Inflammatory markers	Blood samples will be obtained and analyzed for interleukin-6 and tumor necrosis factor alpha	Once at baseline
Inflammatory markers	Blood samples will be obtained and analyzed for interleukin-6 and tumor necrosis factor alpha	Once 30 minutes into the 1-hour yoga session
Inflammatory markers	Blood samples will be obtained and analyzed for interleukin-6 and tumor necrosis factor alpha	Once immediately after the 1-hour yoga session

Collaborators and Investigators

• Sponsor: Texas State University

Study record dates

Study Major Dates

• Study Start (Anticipated): January 15, 2020
• Primary Completion (Anticipated): June 1, 2020
• Study Completion (Anticipated): July 1, 2020

Study Registration Dates

• First Submitted: January 8, 2020
• First Submitted That Met QC Criteria: October 25, 2022
• First Posted (Actual): October 28, 2022

Study Record Updates

• Last Update Posted (Actual): October 28, 2022
• Last Update Submitted That Met QC Criteria: October 25, 2022
• Last Verified: January 1, 2020

More Information

Terms related to this study

• Other Study ID Numbers: 6877

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: No

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No