Muscle Oxygenation in Treadmill and Cycle Ergometer Exercise

Comparison of Oxygenation of the Vastus Lateralis Muscle During Cycling and Treadmill Exercises

The study will be conducted on healthy young adults. Hemodynamic effects such as heart rate, blood pressure, oxygen saturation (SpO2), including muscle oxygenation, will be compared in treadmill and bicycle exercises.

Study Overview

• Status: Not yet recruiting
• Conditions: Muscle Oxygenation; Treadmill
• Intervention / Treatment: Other: Questionnare; Device: Moxy Muscle Oxygen Monitor

Detailed Description

In recent studies, sensor systems that measure the oxygen level in muscle tissue at the microvascular level have been developed. These devices working with Near Infrared Spectroscopy (NIRS, 630-850 nm) method; It provides measurements of muscle oxygenation level at rest and during exercise. It is known that significant changes in vastus lateralis oxygenation levels measured by the NIRS method are associated with various factors such as exercise intensity, exercise profile and training. The aim of this study is to measure the oxygenation level of the vastus lateralis muscle during the exercises performed on the treadmill and bicycle ergometer, and thus to reveal the effect of using different ergometers on fatigue and sportive performance.

Muscle oxygen levels will be measured and evaluated before, during and after exertion. In addition, blood pressure (BP), oxygen saturation (SpO2), dyspnea and fatigue parameters will be recorded and evaluated. If undesirable symptoms are observed during our study, the exercise will be terminated. Within the scope of the project, the acute effect will be examined with the measurements made with the Moxy device on the vastus lateralis muscle during the treadmill and bicycle ergonometer.

• Study Type: Interventional
• Enrollment (Anticipated): 32
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Esra PEHLİVAN, Assoc. Prof.; Phone Number: 2015 0216 346 36 36; Email: esra.pehlivan@sbu.edu.tr
• Study Contact Backup: Name: Dilara KALAYCI; Email: dilarakalayyci@gmail.com

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 14 years to 21 years (Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• Volunteering to participate in the study
• No known disease
• Be between the ages of 18-25

Exclusion Criteria:

• Having cardiopulmonary disease,
• Have had lower extremity muscle or joint injuries
• Having an orthopedic/neurological disorder
• Smoking and alcohol use,
• Have suffered a lower extremity muscle or joint injury,
• Having an orthopedic/neurological disorder,
• Uncontrollable asthma,
• PaO2< 50 mmHg,
• PaCO2> 70mmHg,
• Individuals with a resting systolic blood pressure of 200 mmHg

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Screening
• Allocation: Randomized
• Interventional Model: Crossover Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Treadmill Group; Hemodynamic effects such as heart rate, blood pressure, oxygen saturation (SpO2), dyspnea and fatigue including muscle oxygenation, will be compared during treadmill exercises.	Other: Questionnare; Measurement of Dyspnea and Fatigue during submaximal exercise with The Modified Borg Scale (MBS).; Device: Moxy Muscle Oxygen Monitor; Measurement of muscle oxygenation with Moxy Muscle Oxygen Monitor.
Experimental: Cycle Group; Hemodynamic effects such as heart rate, blood pressure, oxygen saturation (SpO2), dyspnea and fatigue including muscle oxygenation, will be compared during cycling exercises.	Other: Questionnare; Measurement of Dyspnea and Fatigue during submaximal exercise with The Modified Borg Scale (MBS).; Device: Moxy Muscle Oxygen Monitor; Measurement of muscle oxygenation with Moxy Muscle Oxygen Monitor.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Measurement of Patient-Reported Dyspnea and Fatigue	Measurement of dyspnea during submaximal exercise with The Modified Borg Dyspnea Scale (MBS).	Baseline
Measurement of Muscle Oxygenation	Measurement of muscle oxygenation with Moxy Monitor.	Baseline

Collaborators and Investigators

• Sponsor: Saglik Bilimleri Universitesi
• Investigators: Study Director: Esra PEHLİVAN, Assoc. Prof., Saglik Bilimleri Universitesi

Study record dates

Study Major Dates

• Study Start (Anticipated): December 30, 2022
• Primary Completion (Anticipated): March 30, 2023
• Study Completion (Anticipated): May 30, 2023

Study Registration Dates

• First Submitted: December 9, 2022
• First Submitted That Met QC Criteria: December 9, 2022
• First Posted (Actual): December 19, 2022

Study Record Updates

• Last Update Posted (Actual): December 19, 2022
• Last Update Submitted That Met QC Criteria: December 9, 2022
• Last Verified: November 1, 2022

More Information

Terms related to this study

• Keywords: exercise; muscle oxygenation; treadmill; cycle; moxy
• Other Study ID Numbers: Muscle_oxygenation

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: No

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No