Intercostal Muscle Oxygenation During Exercise Tests

Effect of Different Exercise Capacity Tests on Intercostal Muscle Oxygenation

The aim of our study is to determine the effects of different exercise capacity tests on intercostal muscle oxygenation and to reveal the effect of changing accessory respiratory muscle oxygenation on exercise test success.

Study Overview

• Status: Recruiting
• Conditions: Muscle Oxygenation
• Intervention / Treatment: Diagnostic test: Six Minute Walking Test; Diagnostic test: Shuttle walking test

Detailed Description

In the study, intercostal muscle oxygenation will be measured in different exercise capacity tests. A total of 32 healthy young women and men between the ages of 18-25 who meet the inclusion criteria and voluntarily agree to participate in the study will be included in the study. The cases will be randomized into 2 groups: Six minute walking test group and incremental shuttle walking test group. Heart rate, oxygen saturation, and fatigue levels will be measured with the modified Borg scale before and after the tests. During the tests, oxygen levels of the intercostal muscles will be monitored with the MOXY device. After sufficient wash out time, the groups will be crossed and different exercise tests will be applied to the cases. The result of our study will provide information about the use of intercostal muscles during different exercise tests. As a result of the study, results that can be interpreted for patient groups with circulatory system, respiratory system and physical limitations will be obtained.

• Study Type: Observational
• Enrollment (Estimated): 32

Contacts and Locations

• Study Contact: Name: Esra Pehlivan; Phone Number: 02164189616; Email: fztesrakambur@yahoo.com
• Study Contact Backup: Name: Eylem Cinkılıç; Email: cinkilic.eylem@gmail.com

Study Locations

• Turkey
  • İstanbul, Turkey, 34668
    • Recruiting
    • University of Health Sciences Turkey
    • Contact: Esra Pehlivan, PhD; Phone Number: +90 216 418 96 16; Email: fztesrakambur@yahoo.com

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: Yes

• Sampling Method: Probability Sample

Study Population

Healthy young adults

Description

Inclusion Criteria:

• Being between the ages of 18-35
• Body Mass Index <25 kg/m²
• Participating in the study voluntarily

Exclusion Criteria:

• Being a smoker
• Presence of any systemic, orthopedic or cardiopulmonary disease that may prevent exercise tests
• Presence of any diagnosed respiratory, vascular and heart disease

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort

Intervention / Treatment

Healthy subjects

Diagnostic test: Six Minute Walking Test; It is applied in a 30 m long corridor in an indoor environment, and the distance walked by the patient in a six-minute period, oxygen saturation, heart rate, and change in dyspnea are recorded. For this, before starting the test, oxygen saturation, heart rate, arterial blood pressure and dyspnea level according to the Borg scale are recorded. The same parameters are measured again at the end of the test. The feature of this test is that the person walks at his own pace, stopping when necessary and allowing the use of oxygen. It is an exercise test that is easy to perform and well tolerated.; Diagnostic test: Shuttle walking test; Shuttle walking test at increasing speed is an exercise test in which walk between two cones 10 m apart at an increasing speed throughout the test and each 10-meter journey between the two cones is counted as a shuttle.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Evaluation of Muscle Oxygenation of intercostal muscles	The measurement will be made with the MOXY device. The device will be placed on the intercostal muscle and measurements will be taken during the exercise tests. Measured values at the beginning, end and every 1 minute will be taken and analyzed.	During intervention

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Forced expiratory pressure in one second	It will be performed with Cosmed Pony Fx (Italy) desktop spirometry device.	Baseline
Evaluation of blood pressure	Sistolik and diastolic blood pressure will be measured with the Wrist Blood Pressure Monitor	During the intervention
Evaluation of heart rate	It will be measured with a pulse oximeter.	During the intervention
Evaluation of oxygen saturation	It will be measured with a pulse oximeter.	During the intervention
Forced vital capacity	It will be performed with Cosmed Pony Fx (Italy) desktop spirometry device.	Baseline

Collaborators and Investigators

• Sponsor: Istanbul Medipol University Hospital

Study record dates

Study Major Dates

• Study Start (Actual): May 10, 2024
• Primary Completion (Estimated): June 1, 2025
• Study Completion (Estimated): June 1, 2025

Study Registration Dates

• First Submitted: May 4, 2024
• First Submitted That Met QC Criteria: May 10, 2024
• First Posted (Actual): May 13, 2024

Study Record Updates

• Last Update Posted (Actual): May 14, 2024
• Last Update Submitted That Met QC Criteria: May 10, 2024
• Last Verified: May 1, 2024

More Information

Terms related to this study

• Keywords: muscle oxygenation; exercise capacity test; intercostal muscle
• Other Study ID Numbers: ICM_Moxy

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No