A Study to Compare Iberdomide Maintenance Versus Lenalidomide Maintenance Therapy Following Autologous Stem Cell Transplant in Participants With Newly Diagnosed Multiple Myeloma

March 12, 2026 updated by: Bristol-Myers Squibb

A Phase 3, Two-stage, Randomized, Multi-center, Controlled, Open-label Study Comparing Iberdomide Maintenance to Lenalidomide Maintenance Therapy After Autologous Stem Cell Transplantation (ASCT) in Participants With Newly Diagnosed Multiple Myeloma (NDMM) (EXCALIBER-Maintenance)

The purpose of this study is to compare the effectiveness of iberdomide maintenance to lenalidomide maintenance therapy after autologous stem cell transplantation (ASCT) in participants with newly diagnosed multiple myeloma (NDMM).

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

1216

Phase

  • Phase 3

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

  • Name: First line of the email MUST contain NCT # and Site #.

Study Contact Backup

  • Name: BMS Clinical Trials Contact Center www.BMSClinicalTrials.com
  • Phone Number: 855-907-3286
  • Email: Clinical.Trials@bms.com

Study Locations

  • Argentina
      • Córdoba, Argentina, X5000JHGQ
        • Recruiting
        • Sanatorio Allende
        • Contact:
          • Gustavo Jarchum, Site 0182
    • B
      • Mar del Plata, B, Argentina, 7600
        • Withdrawn
        • Local Institution - 0259
      • Pilar, B, Argentina, B1629AHJ
        • Recruiting
        • Hospital Universitario Austral
        • Contact:
          • Mariano Berro, Site 0267
          • Phone Number: +5491140799721
    • Buenos Aires F.D.
      • Ciudad Autonoma Buenos Aires, Buenos Aires F.D., Argentina, C1199ABB
        • Recruiting
        • Hospital Italiano de Buenos Aires
        • Contact:
          • Dorotea Fantl, Site 0183
          • Phone Number: 005491151097180
      • Ciudad Autonoma Buenos Aires, Buenos Aires F.D., Argentina, C1430EFA
        • Recruiting
        • "Centro de Educación Médica e Investigaciones Clínicas ""Norberto Quirno"""
        • Contact:
          • Patricio Duarte, Site 0227
          • Phone Number: 911052990100
  • Australia
    • New South Wales
      • Waratah, New South Wales, Australia, 2298
        • Recruiting
        • Calvary Mater Newcastle
        • Contact:
          • Wojt Janowski, Site 0244
          • Phone Number: 0415572214
    • South Australia
      • Adelaide, South Australia, Australia, 5000
        • Recruiting
        • Royal Adelaide Hospital
        • Contact:
          • Akash Kalro, Site 0088
          • Phone Number: +0870743290
    • Victoria
      • Box Hill, Victoria, Australia, 3128
        • Recruiting
        • Box Hill Hospital
        • Contact:
          • Olga Motorna, Site 0220
          • Phone Number: +61 3 9094 9516
      • Clayton, Victoria, Australia, 3800
        • Recruiting
        • Monash Health
        • Contact:
          • Michael Low, Site 0078
          • Phone Number: 0412853153
  • Austria
      • Linz, Austria, 4020
        • Recruiting
        • Ordensklinikum Linz Elisabethinen
        • Contact:
          • Irene Strassl, Site 0058
          • Phone Number: +004373276764411
      • Sankt Pölten, Austria, 3100
        • Recruiting
        • Universitätsklinikum St. Pölten
        • Contact:
          • Petra Pichler, Site 0034
          • Phone Number: +00432742900422181
      • Vienna, Austria, 1140
        • Recruiting
        • Hanusch-Krankenhaus
        • Contact:
          • Michael Fillitz, Site 0275
          • Phone Number: +4319102185500
      • Vienna, Austria, 1090
        • Recruiting
        • Medizinische Universitaet Wien - Universitaetsklinik fuer Augenheilkunde und Optometrie
        • Contact:
          • Maria-Theresa Krauth, Site 0056
          • Phone Number: 004314040044100
  • Belgium
      • Kortrijk, Belgium, 8500
        • Recruiting
        • AZ Groeninge - campus kennedylaan
        • Contact:
          • Koen Maes, Site 0048
          • Phone Number: +32056234305
    • WHT
      • Charleroi, WHT, Belgium, 6060
        • Recruiting
        • Grand Hôpital de Charleroi - Les Viviers
        • Contact:
          • Geraldine Verstraete, Site 0035
          • Phone Number: 003271104260
  • Brazil
      • Barretos, Brazil, 14784-400
        • Recruiting
        • Hospital de Cancer de Barretos - Fundacao Pio XII
        • Contact:
          • Gilberto Colli, Site 0190
          • Phone Number: 551733216637
      • Porto Alegre, Brazil, 90880-480
        • Recruiting
        • Hospital Mae de Deus
        • Contact:
          • Marcelo Eduardo Capra, Site 0083
          • Phone Number: +555133072943
      • Rio de Janeiro, Brazil, 21941-913
        • Recruiting
        • Instituto COI de Pesquisa, Educação e Gestão
        • Contact:
          • Angelo Maiolino, Site 0096
          • Phone Number: +5521981116663
      • Salvador, Brazil, 40110-150
        • Recruiting
        • Hospital Sao Rafael
        • Contact:
          • EDVAN CRUSOE, Site 0098
          • Phone Number: 557132816965
    • Paraná
      • Curitiba, Paraná, Brazil, 80520-174
        • Withdrawn
        • Local Institution - 0245
    • Rio de Janeiro
      • Niterói, Rio de Janeiro, Brazil, 24020-096
        • Recruiting
        • CHN - Complexo Hospitalar de Niterói
        • Contact:
          • Jacques Kaufman, Site 0214
          • Phone Number: +5521995012090
      • Rio de Janeiro, Rio de Janeiro, Brazil, 20230-130
        • Recruiting
        • Instituto Nacional de Câncer
        • Contact:
          • Luciana Barreto Herriot, Site 0082
          • Phone Number: +552132071246
    • São Paulo
      • Ribeirão Preto, São Paulo, Brazil, 14051-140
        • Recruiting
        • Hospital Das Clinicas Da Faculdade De Medicina De Ribeirao Preto da Universidade de Sao Paulo
        • Contact:
          • Pedro Manoel Marques Garibaldi, Site 0081
          • Phone Number: +5516982488425
      • São Paulo, São Paulo, Brazil, 05403-000
        • Recruiting
        • Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
        • Contact:
          • Fernanda Seguro, Site 0194
      • São Paulo, São Paulo, Brazil, 04537-080
        • Recruiting
        • Clinica Medica Sao Germano
        • Contact:
          • Vania Hungria, Site 0277
          • Phone Number: +5511999346820
      • São Paulo, São Paulo, Brazil, 08270-070
        • Recruiting
        • Hospital Santa Marcelina
        • Contact:
          • Larissa Barchi Muniz, Site 0241
          • Phone Number: +5511944488936
  • Canada
    • Alberta
      • Edmonton, Alberta, Canada, T6G 1Z2
        • Recruiting
        • Cross Cancer Institute
        • Contact:
          • Irwindeep Sandhu, Site 0270
          • Phone Number: 7804071993
    • Ontario
      • Ottawa, Ontario, Canada, K1H 8L6
        • Recruiting
        • The Ottawa Hospital - General Campus
        • Contact:
          • Arleigh McCurdy, Site 0208
          • Phone Number: 613-915-0411
    • Quebec
      • Montreal, Quebec, Canada, H3T 1E2
        • Recruiting
        • Jewish General Hospital
        • Contact:
          • Rayan Kaedbey, Site 0307
          • Phone Number: 514-340-8222x28658
      • Québec, Quebec, Canada
        • Recruiting
        • CHUQ - The Hôtel-Dieu de Québec
        • Contact:
          • Marc Lalancette, Site 0210
          • Phone Number: 4186915225
  • Chile
      • Santiago, Chile, 7500691
        • Recruiting
        • Fundacion Arturo Lopez Perez
        • Contact:
          • Raimundo Gazitua Pepper, Site 0186
          • Phone Number: +56984290128
      • Temuco, Chile, 4800827
        • Active, not recruiting
        • Local Institution - 0258
      • Vitacura, Chile, 7650567
        • Recruiting
        • Clinica Alemana - Vitacura
        • Contact:
          • Javiera Donoso, Site 0099
          • Phone Number: 56999402396
  • China
      • Beijing, China, 100044
        • Recruiting
        • Peking University People's Hospital
        • Contact:
          • Jin Lu, Site 0216
          • Phone Number: 861088314422
      • Beijing, China, 100020
        • Recruiting
        • Beijing Chaoyang Hospital, Capital Medical University
        • Contact:
          • Wen Gao, Site 0100
      • Changsha, China, 400011
        • Recruiting
        • The second Xiangya hospital of central south university
        • Contact:
          • hongling peng, Site 0234
          • Phone Number: 13975806137
      • Fuzhou, China, 350001
        • Recruiting
        • Fujian Medical University Union Hospital
        • Contact:
          • Rong Zhan, Site 0273
          • Phone Number: 8613705080893
      • Guangzhou, China, 511363
        • Recruiting
        • Sun Yat-sen University Cancer Center
        • Contact:
          • Zhongjun Xia, Site 0079
          • Phone Number: 8613602713223
      • Jinan, China, 250021
        • Recruiting
        • Shandong Provincial Hospital
        • Contact:
          • Xiangxiang Zhou, Site 0212
          • Phone Number: 8615866695595
      • Nanjing, China, 210029
        • Recruiting
        • Jiangsu Province Hospital
        • Contact:
          • Lijuan Chen, Site 0231
          • Phone Number: +8615850521836
      • Qingdao, China, 266071
        • Recruiting
        • Qingdao Municipal Hospital
        • Contact:
          • Yuping Zhong, Site 0077
          • Phone Number: +8613501098223
      • Shanghai, China, 200025
        • Recruiting
        • Ruijin Hospital Affiliated to The Shanghai Jiao Tong University Medical School
        • Contact:
          • Jianqing Mi, Site 0223
      • Suzhou, China, 215006
        • Recruiting
        • The First Affiliated Hospital of Soochow University
        • Contact:
          • Chengcheng Fu, Site 0305
      • Wenzhou, China, 325000
        • Recruiting
        • Wenzhou Medical University - The First Affiliated Hospital
        • Contact:
          • Song-Fu Jiang, Site 0087
          • Phone Number: 8613968806622
      • Wuhan, China, 430030
        • Recruiting
        • Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology
        • Contact:
          • Chunrui Li, Site 0084
          • Phone Number: +8602783662680
      • Wuhan, China, 430022
        • Recruiting
        • Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
        • Contact:
          • Yu Hu, Site 0248
          • Phone Number: 027-85726685
    • AH
      • Hefei, AH, China, 230001
        • Recruiting
        • Anhui Provincial Hospital
        • Contact:
          • Yongsheng Han, Site 0196
    • BJ
      • Beijing, BJ, China, 100038
        • Active, not recruiting
        • Local Institution - 0326
    • Beijing Municipality
      • Beijing, Beijing Municipality, China, 100071
        • Recruiting
        • The Fifth Medical Center of People's Liberation Army General Hospital
        • Contact:
          • Wenrong Huang, Site 0229
          • Phone Number: +86 15010955827
    • CQ
      • Chongqing, CQ, China, 400030
        • Not yet recruiting
        • Local Institution - 0321
        • Contact:
          • Site 0321
    • Chongqing Municipality
      • Chongqing, Chongqing Municipality, China, 400016
        • Recruiting
        • The First Affiliated Hospital of Chongqing Medical University
        • Contact:
          • Hongbin Zhang, Site 0242
          • Phone Number: 13883110505
    • GD
      • Guangzhou, GD, China, 510515
        • Recruiting
        • Nanfang Hospital of Southern Medical University
        • Contact:
          • Xiaolei Wei, Site 0304
          • Phone Number: 13826407312
    • Guangdong
      • Guangzhou, Guangdong, China, 510080
        • Recruiting
        • Guangdong Provincial People's Hospital
        • Contact:
          • Xin Du, Site 0261
          • Phone Number: 8602083827812
      • Shenzhen, Guangdong, China, 518028
        • Recruiting
        • Shenzhen Second People's Hospital
        • Contact:
          • Xin Du, Site 0256
          • Phone Number: 13602523722
    • HN
      • Changsha, HN, China, 410013
        • Recruiting
        • The Third Xiangya Hospital of Central South University
        • Contact:
          • Xin Li, Site 0282
          • Phone Number: 8613808418932
      • Changsha, HN, China, 410013
        • Recruiting
        • Xiangya Hospital, Central South University
        • Contact:
          • yanjuan He, Site 0262
          • Phone Number: 15973130688
    • Henan
      • Zhengzhou, Henan, China, 450003
        • Recruiting
        • Henan Cancer Hospital
        • Contact:
          • Baijun Fang, Site 0246
          • Phone Number: 13526607830
    • JL
      • Changchun, JL, China, 130021
        • Recruiting
        • The First Hospital of Jilin University
        • Contact:
          • sujun gao, Site 0091
          • Phone Number: +86 15843073208
    • Jiangsu
      • Nanjing, Jiangsu, China, 210008
        • Recruiting
        • Nanjing Drum Tower Hospital - The Comprehensive Cancer Center
        • Contact:
          • Bing Chen, Site 0266
          • Phone Number: 8613951806490
      • Xuzhou, Jiangsu, China, 221000
        • Recruiting
        • The Affiliated Hospital of Xuzhou Medical University
        • Contact:
          • Zhenyu Li, Site 0239
          • Phone Number: +8615950688971
    • Jiangxi
      • Nanchang, Jiangxi, China, 330200
        • Active, not recruiting
        • Local Institution - 0263
    • Liaoning
      • Shenyang, Liaoning, China, 110022
        • Active, not recruiting
        • Local Institution - 0094
    • SD
      • Jinan, SD, China, 250012
        • Recruiting
        • Qilu Hospital of Shandong University
        • Contact:
          • Ming Hou, Site 0240
          • Phone Number: 8613791122627
    • SH
      • Shanghai, SH, China, 200434
        • Recruiting
        • Shanghai Fourth People's Hospital
        • Contact:
          • Weijun Fu, Site 0319
          • Phone Number: +8613816052522
    • Shaanxi
      • Xi'an, Shaanxi, China, 710061
        • Recruiting
        • The First Affiliated Hospital of Xi'an Jiaotong University
        • Contact:
          • Pengcheng He, Site 0318
          • Phone Number: +8618991232609
      • Xi'an, Shaanxi, China, 710032
        • Recruiting
        • The First Affiliated Hospital of the Air Force Medical University
        • Contact:
          • Guangxun Gao, Site 0265
          • Phone Number: +8613991907320
    • Shanghai Municipality
      • Shanghai, Shanghai Municipality, China, 200003
        • Withdrawn
        • Local Institution - 0271
    • Tianjin Municipality
      • Tianjin, Tianjin Municipality, China, 300060
        • Recruiting
        • Tianjin Medical University Cancer Institute and Hospital
        • Contact:
          • Yafei Wang, Site 0249
          • Phone Number: +8602260177666
    • ZJ
      • Hangzhou, ZJ, China, 310003
        • Recruiting
        • The First Affiliated Hospital - Zhejiang University School of Medicine
        • Contact:
          • Haitao Meng, Site 0243
          • Phone Number: 13989823604
      • Ningbo, ZJ, China, 315010
        • Recruiting
        • The First Affiliated Hospital of Ningbo University
        • Contact:
          • Guifang Ouyang, Site 0320
          • Phone Number: 13967810405
  • Colombia
      • Bogotá, Colombia, 110111
        • Recruiting
        • Instituto Nacional de Cancerología - Bogota
        • Contact:
          • Juan Ospina, Site 0217
          • Phone Number: +573104296085
      • Bogotá, Colombia, 110131
        • Recruiting
        • Fundacion Centro de Tratamiento e Investigacion sobre Cancer Luis Carlos Sarmiento Angulo - CTIC
        • Contact:
          • Virginia Abello, Site 0211
          • Phone Number: +57573153455399
      • Floridablanca, Colombia, 681004
        • Recruiting
        • Fundacion Oftalmologica de Santander - FOSCAL
        • Contact:
          • Claudia Sossa, Site 0101
          • Phone Number: +05776399658
      • Medellín, Colombia, 050034
        • Recruiting
        • Hospital Pablo Tobon Uribe
        • Contact:
          • Kenny Galvez, Site 0179
          • Phone Number: 5731489056030000
      • Valledupar, Colombia, 200001
        • Recruiting
        • Sociedad de Oncologia y Hematologia del Cesar S.A.S
        • Contact:
          • Carmen Rosales Oliveros, Site 0093
          • Phone Number: +573112620177
    • COR
      • Montería, COR, Colombia, 230002
        • Recruiting
        • Oncomedica S.A.
        • Contact:
          • Leivi Correa Negrete, Site 0302
  • Czechia
      • Brno, Czechia, 625 00
        • Recruiting
        • Fakultni nemocnice Brno
        • Contact:
          • Ludek Pour, Site 0036
          • Phone Number: +420532233551
      • Olomouc, Czechia, 779 00
        • Recruiting
        • Fakultni nemocnice Olomouc
        • Contact:
          • Tomas Pika, Site 0206
          • Phone Number: +420588445351
      • Prague, Czechia, 128 08
        • Recruiting
        • Vseobecna Fakultní Nemocnice
        • Contact:
          • Ivan Spicka, Site 0069
          • Phone Number: 420224966326
      • Prague, Czechia, 100 34
        • Recruiting
        • Fakultni nemocnice Kralovske Vinohrady
        • Contact:
          • Petr Pavlicek, Site 0215
          • Phone Number: +420267163188
  • Denmark
      • Odense, Denmark, 5000
        • Recruiting
        • Odense Universitetshospital
        • Contact:
          • Jakub Krejcik, Site 0028
          • Phone Number: +4540337294
  • Finland
      • Helsinki, Finland, 00290
        • Recruiting
        • Helsingin Yliopistollinen Sairaala (HUS) - Syopakeskus (Comprehensive Cancer Center)
        • Contact:
          • Sini Luoma, Site 0276
          • Phone Number: +358504390325
      • Kuopio, Finland, 70211
        • Recruiting
        • Kuopio University Hospital
        • Contact:
          • Anu Partanen, Site 0201
  • France
      • Amiens, France, 80000
        • Recruiting
        • CHU Hopital Sud
        • Contact:
          • Lydia Montes, Site 0030
          • Phone Number: +0322455914
      • Caen, France, 14033
        • Recruiting
        • Institut d'Hématologie de Basse-Normandie (IHBN)
        • Contact:
          • Margaret Macro, Site 0055
          • Phone Number: +33231272539 000000
      • Créteil, France, 94000
        • Recruiting
        • CHU Hôpital Henri Mondor
        • Contact:
          • Karim Belhadj, Site 0050
          • Phone Number: +33149812163
      • La Roche-sur-Yon, France, 85000
        • Recruiting
        • Centre Hospitalier Départemental Vendée - Hôpital de la Roche-sur-Yon
        • Contact:
          • Komivi AGBETSIVI, Site 0236
          • Phone Number: +33251446572
      • Lille, France, 59037
        • Recruiting
        • Centre Hospitalier Régional Universitaire de Lille (CHRU) - Hôpital Claude Huriez
        • Contact:
          • Salomon Manier, Site 0054
          • Phone Number: 33320444292
      • Limoges, France, 87042
        • Recruiting
        • CHU Limoges - Hopital Dupuytren
        • Contact:
          • Murielle Roussel, Site 0221
          • Phone Number: +33555056651
      • Nantes, France, 44093
        • Recruiting
        • Centre Hospitalier Universitaire de Nantes (Chu de Nantes) - Hotel-Dieu
        • Contact:
          • Cyrille Touzeau, Site 0272
          • Phone Number: 33240083271
      • Paris, France, 75012
        • Recruiting
        • Hopital Saint-Antoine
        • Contact:
          • Mohamad Mohty, Site 0219
          • Phone Number: 33149282620
      • Paris, France, 75013
        • Recruiting
        • Hôpital Pitié-Salpêtrière
        • Contact:
          • Laurent Garderet, Site 0228
          • Phone Number: +33148282624
      • Toulouse, France, 31059
        • Recruiting
        • Institut Universitaire du Cancer de Toulouse - Oncopole
        • Contact:
          • Aurore Perrot, Site 0051
          • Phone Number: 0531156184
  • Germany
      • Freiburg im Breisgau, Germany, 79106
        • Recruiting
        • Universitatsklinikum Freiburg
        • Contact:
          • Monika Engelhardt, Site 0045
          • Phone Number: +4976127033180
      • Göttingen, Germany, 37075
        • Withdrawn
        • Local Institution - 0310
      • Hamburg, Germany, 20246
        • Recruiting
        • Universitätsklinikum Hamburg-Eppendorf (UKE)
        • Contact:
          • Katja Weisel, Site 0297
          • Phone Number: 4970712989200
      • Hamm, Germany, 59073
        • Recruiting
        • St. Barbara-Klinik Hamm-Heessen GmbH
        • Contact:
          • Heinz Duerk, Site 0026
          • Phone Number: 4923816811535
      • Jena, Germany, 07747
        • Recruiting
        • Universitatsklinikum Jena
        • Contact:
          • Olaposi Yomade, Site 0038
          • Phone Number: +4936419324577
      • Marburg, Germany, 35033
        • Withdrawn
        • Local Institution - 0323
      • Tübingen, Germany, 72076
        • Recruiting
        • Universitatsklinikum Tubingen
        • Contact:
          • Britta Besemer, Site 0040
          • Phone Number: 4970712982711
    • Baden-Wurttemberg
      • Ulm, Baden-Wurttemberg, Germany, 89081
        • Recruiting
        • Universitatsklinikum Ulm
        • Contact:
          • Miriam Kull, Site 0092
          • Phone Number: 073150045540
    • Bavaria
      • Augsburg, Bavaria, Germany, 86156
        • Recruiting
        • Klinikum Augsburg
        • Contact:
          • Tim Pfeiffer, Site 0324
          • Phone Number: 00498214002362
      • Bayreuth, Bavaria, Germany, 95445
        • Recruiting
        • Klinikum Bayreuth GmbH
        • Contact:
          • Alexander Kiani, Site 0312
          • Phone Number: 09214006302
      • Erlangen, Bavaria, Germany, 91054
        • Recruiting
        • Universitaetsklinikum Erlangen - Medizinische Klinik 5
        • Contact:
          • Barbara Ferstl, Site 0298
          • Phone Number: +49913108533409
      • Munich, Bavaria, Germany, 81377
        • Recruiting
        • LMU Klinikum der Universitaet Muenchen - Campus Grosshadern - Transplantation
        • Contact:
          • Sebastian Theurich, Site 0311
          • Phone Number: +49015254849028
    • Brandenburg
      • Cottbus, Brandenburg, Germany, 03048
        • Recruiting
        • Carl-Thiem-Klinikum Cottbus GmbH
        • Contact:
          • Martin Schmidt-Hieber, Site 0314
          • Phone Number: +49(0)355462220
    • Hamburg
      • Hamburg, Hamburg, Germany, 22763
        • Recruiting
        • Asklepios Klinik Altona
        • Contact:
          • Hans Salwender, Site 0315
          • Phone Number: +49401818811211 -00-
    • Lower Saxony
      • Hildesheim, Lower Saxony, Germany, 31134
        • Withdrawn
        • Local Institution - 0313
    • Saxony
      • Chemnitz, Saxony, Germany, 09116
        • Recruiting
        • Klinikum Chemnitz gGmbH
        • Contact:
          • Mathias Haenel, Site 0316
          • Phone Number: 4937133344500
    • State of Berlin
      • Berlin, State of Berlin, Germany, 12203
        • Recruiting
        • Charite-Universitaetsmedizin Berlin - Campus Benjamin Franklin (CBF)
        • Contact:
          • Jana Riederer, Site 0037
          • Phone Number: 093120126762
  • Greece
      • Athens, Greece, 115 28
        • Recruiting
        • Alexandra General Hospital of Athens
        • Contact:
          • Meletios Dimopoulos, Site 0233
          • Phone Number: +302107488941
      • Larissa, Greece, 411 10
        • Recruiting
        • University of Thessaly- General University Hospital of Larissa
        • Contact:
          • George Vasilopoulos, Site 0290
          • Phone Number: +306949207498
      • Thessaloniki, Greece, 546 39
        • Recruiting
        • Theageneio Cancer Hospital of Thessaloniki
        • Contact:
          • Eirini Katodritou, Site 0063
    • B
      • Thessaloniki, B, Greece, 570 10
        • Recruiting
        • "General Hospital of Thessaloniki ""G. Papanikolaou"""
        • Contact:
          • Ioanna Sakellari, Site 0209
    • G
      • Rio, G, Greece, 265 04
        • Recruiting
        • University of Patras - Rio Regional University Hospital
        • Contact:
          • Alexandros Spyridonidis, Site 0097
          • Phone Number: 306977448977
    • I
      • Athens, I, Greece, 106 76
        • Recruiting
        • Evangelismos General Hospital of Athens
        • Contact:
          • Sosana Delimpasi, Site 0185
          • Phone Number: 6944822722
  • Hong Kong
    • HK
      • Hong Kong, HK, Hong Kong, 999077
        • Recruiting
        • Queen Mary Hospital
        • Contact:
          • Yok Lam Kwong, Site 0250
          • Phone Number: 85222555859
  • Hungary
    • HB
      • Debrecen, HB, Hungary, 4032
        • Recruiting
        • Debreceni Egyetem Klinikai Központ III. sz. Belgyógyászati Klinika
        • Contact:
          • Arpad Illes, Site 0062
          • Phone Number: +36309454801
  • India
      • Navi Mumbai, India, 410 210
        • Withdrawn
        • Local Institution - 0135
    • Chandigarh
      • Chandigarh, Chandigarh, India, 160012
        • Recruiting
        • Postgraduate Institute of Medical Education & Research (PGIMER)
        • Contact:
          • Pankaj Malhotra, Site 0128
          • Phone Number: 911722756680
    • Karnataka
      • Bangalore, Karnataka, India, 560027
        • Recruiting
        • HCG Cancer Center - Kalinga Rao Road
        • Contact:
          • Satheesh Thungappa, Site 0110
          • Phone Number: +919242698750
    • Kerala
      • Kochi, Kerala, India, 68202
        • Recruiting
        • Aster Medcity
        • Contact:
          • Deepak Charles, Site 0109
          • Phone Number: +9447233902
    • Maharashtra
      • Kolhāpur, Maharashtra, India, 416005
        • Recruiting
        • Dr. Bafnas Star Superspecaility Clinic and Hospital
        • Contact:
          • Varun Bafna, Site 0200
          • Phone Number: 9075971726
      • Nagpur, Maharashtra, India, 440030
        • Recruiting
        • Alexis Multispeciality Hospital
        • Contact:
          • Amol Shank Dongre, Site 0152
          • Phone Number: +9823311569
      • Pune, Maharashtra, India, 411004
        • Recruiting
        • Sahyadri Super Speciality Hospital
        • Contact:
          • Shashikant Apte, Site 0142
          • Phone Number: +919822404983
      • Pune, Maharashtra, India, 411 004
        • Recruiting
        • Deenanath Mangeshkar Hospital & Research Center
        • Contact:
          • Sameer Melinkeri, Site 0123
          • Phone Number: 9766249644
    • Odisha
      • Bhubaneswar, Odisha, India, 751007
        • Recruiting
        • Sparsh Hospitals & Critical Care
        • Contact:
          • Ghanashyam Biswas, Site 0124
          • Phone Number: +919937500878
    • West Bengal
      • Kolkata, West Bengal, India, 700160
        • Recruiting
        • Tata Medical Center
        • Contact:
          • Jeevan Kumar, Site 0125
          • Phone Number: +91-9007016755
  • Israel
      • Ashdod, Israel, 7747629
        • Recruiting
        • Assuta Medical Center
        • Contact:
          • Merav Leiba, Site 0057
          • Phone Number: 972-586669161
      • Beer Ya'Aqov, Israel, 70300
        • Recruiting
        • Assaf Harofeh Medical Center
        • Contact:
          • Katrin Herzog-Tzarfati, Site 0137
          • Phone Number: +97289779768
      • Hadera, Israel, 38100
        • Recruiting
        • Hillel Yaffe Medical Center
        • Contact:
          • Orit Sofer, Site 0027
          • Phone Number: +972506246776
      • Haifa, Israel, 3109601
        • Recruiting
        • Rambam Medical Center
        • Contact:
          • Noa Lavi, Site 0047
          • Phone Number: 97248542541
      • Jerusalem, Israel, 91031
        • Recruiting
        • Shaare Zedek Medical Center
        • Contact:
          • Chezi Ganzel, Site 0075
          • Phone Number: +972533342046
      • Jerusalem, Israel, 9112001
        • Recruiting
        • Hadassah University Medical Center
        • Contact:
          • Moshe Gatt, Site 0060
          • Phone Number: 97226779268
      • Petah Tikva, Israel, 49100
        • Recruiting
        • Rabin Medical Center - Davidoff Center
        • Contact:
          • Iuliana Vaxman, Site 0108
          • Phone Number: 972547994003
      • Ramat Gan, Israel, 52621
        • Recruiting
        • The Chaim Sheba Medical Center
        • Contact:
          • Hila Magen, Site 0131
          • Phone Number: 972504065462
      • Tel Aviv, Israel, 64239
        • Withdrawn
        • Local Institution - 0136
  • Italy
      • Naples, Italy, 80131
        • Recruiting
        • "Azienda Ospedaliera Universitaria ""Federico II"""
        • Contact:
          • Fabrizio Pane, Site 0074
          • Phone Number: +390817462037
      • Pavia, Italy, 27100
        • Recruiting
        • Fondazione IRCCS Policlinico San Matteo
        • Contact:
          • Silvia Mangiacavalli, Site 0278
          • Phone Number: +003903822501308
      • Rome, Italy, 00161
        • Recruiting
        • Policlinico Umberto I
        • Contact:
          • Maurizio Martelli, Site 0065
          • Phone Number: 3906857951
    • CT
      • Catania, CT, Italy, 95123
        • Recruiting
        • Azienda Ospedaliero Universitaria Policlinico G. Rodolico San Marco - Ospedale San Marco
        • Contact:
          • Francesco Di Raimondo, Site 0053
          • Phone Number: +0390957436261
    • FI
      • Florence, FI, Italy, 50134
        • Recruiting
        • Azienda Ospedaliero-Universitaria Careggi
        • Contact:
          • Elisabetta Antonioli, Site 0306
          • Phone Number: +39055794111
    • GE
      • Genova, GE, Italy, 16132
        • Recruiting
        • Ospedale Policlinico San Martino
        • Contact:
          • Michele Cea, Site 0115
    • MI
      • Milan, MI, Italy, 20122
        • Recruiting
        • Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico
        • Contact:
          • Loredana Pettine, Site 0188
          • Phone Number: +390255033477
      • Milan, MI, Italy, 20162
        • Recruiting
        • ASST Grande Ospedale Metropolitano Niguarda
        • Contact:
          • Anna Cafro, Site 0071
          • Phone Number: +0264442668
    • PI
      • Pisa, PI, Italy, 56127
        • Recruiting
        • Azienda Ospedaliero Universitaria Pisana - Ospedale Santa Chiara
        • Contact:
          • Gabriele Buda, Site 0139
          • Phone Number: 050993025
    • RM
      • Roma, RM, Italy, 00168
        • Recruiting
        • Fondazione Policlinico Universitario Agostino Gemelli
        • Contact:
          • valerio de stefano, Site 0046
          • Phone Number: +39 0630154206
    • TO
      • Torino, TO, Italy, 10126
        • Recruiting
        • Azienda Ospedaliera Universitaria Citta della Salute e della Scienza di Torino - Ospedale Molinette
        • Contact:
          • Francesca Maria Gay, Site 0140
          • Phone Number: +390116334279
  • Japan
      • Chiba, Japan, 260-8677
        • Recruiting
        • Chiba University Hospital
        • Contact:
          • Emiko Sakaida, Site 0141
          • Phone Number: +81432227171
      • Gifu, Japan, 500-8513
        • Recruiting
        • Gifu Municipal Hospital
        • Contact:
          • Senji Kasahara, Site 0118
          • Phone Number: +0582511101
      • Higashiibaraki-Gun, Japan, 311-3193
        • Not yet recruiting
        • Local Institution - 0133
        • Contact:
          • Site 0133
      • Hiroshima, Japan, 730-8619
        • Recruiting
        • Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital
        • Contact:
          • Mitsuhiro Itagaki, Site 0112
          • Phone Number: +81-82-241-3111
      • Isehara-shi, Japan, 259-1193
        • Recruiting
        • Tokai University Hospital
        • Contact:
          • Yoshiaki Ogawa, Site 0199
      • Itabashi-Ku, Japan, 173-8610
        • Recruiting
        • Nihon University Itabashi Hospital
        • Contact:
          • Katsuhiro Miura, Site 0330
          • Phone Number: +81-(0)3-3972-8111
      • Kagoshima, Japan, 890-8520
        • Recruiting
        • Kagoshima University Hospital
        • Contact:
          • Kenji Ishitsuka, Site 0111
          • Phone Number: +81992755945
      • Kanazawa, Japan, 920-8641
        • Recruiting
        • Kanazawa University Hospital
        • Contact:
          • Hiroyuki Takamatsu, Site 0144
          • Phone Number: +8109094405616
      • Kobe, Japan, 650-0047
        • Not yet recruiting
        • Local Institution - 0134
        • Contact:
          • Site 0134
      • Kōtoku, Japan, 135-8550
        • Recruiting
        • The Cancer Institute Hospital of Japanese Foundation for Cancer Research (JFCR)
        • Contact:
          • Dai Maruyama, Site 0122
          • Phone Number: +81-3-3520-0111
      • Maebashi, Japan, 371-8511
        • Recruiting
        • Gunma University Hospital
        • Contact:
          • Hiroshi Handa, Site 0121
          • Phone Number: +81272208741
      • Minatoku, Japan, 105-8471
        • Recruiting
        • The Jikei University Hospital
        • Contact:
          • Shingo Yano, Site 0150
          • Phone Number: 81-3-3433-1111
      • Nagasaki, Japan, 852-8511
        • Recruiting
        • The Japanese Red Cross Nagasaki Genbaku Hospital
        • Contact:
          • Jun Taguchi, Site 0104
          • Phone Number: +81-95-847-1511
      • Nagoya, Japan, 467-8602
        • Recruiting
        • Nagoya City University Hospital
        • Contact:
          • Shinsuke Iida, Site 0143
          • Phone Number: 81528515511
      • Nerima-Ku, Japan, 179-0072
        • Recruiting
        • Nerima Hikarigaoka Hospital
        • Contact:
          • Naoki Takezako, Site 0329
      • Saitama-shi, Japan, 330-8503
        • Recruiting
        • Jichi Medical University Saitama Medical Center
        • Contact:
          • Nozomu Yoshino, Site 0148
          • Phone Number: +81285587353
      • Sakaishi, Japan, 590-0197
        • Recruiting
        • Kindai University Hospital
        • Contact:
          • Hirokazu Tanaka, Site 0268
          • Phone Number: 81723660221
      • Sapporo, Japan, 003-0006
        • Recruiting
        • Sapporo Hokuyu Hospital
        • Contact:
          • Shuichi Ota, Site 0105
          • Phone Number: +81118650111
      • Sendai, Japan, 983-8520
        • Recruiting
        • National Hospital Organization Sendai Medical Center
        • Contact:
          • Toru Izumi, Site 0132
          • Phone Number: +810222931111
      • Shibuya-ku, Japan, 150-8935
        • Recruiting
        • Japanese Red Cross Medical Center
        • Contact:
          • Tadao Ishida, Site 0116
          • Phone Number: 8133400104
    • Gunma
      • Shibukawa-shi, Gunma, Japan, 3770280
        • Recruiting
        • National Hospital Organization (NHO) - Shibukawa Medical Center
        • Contact:
          • Akio Saito, Site 0106
          • Phone Number: +81279231010
    • Kanagawa
      • Kamakura-Shi, Kanagawa, Japan, 2478533
        • Recruiting
        • Shonan Kamakura General Hospital
        • Contact:
          • Tomiteru Togano, Site 0197
          • Phone Number: +81-467-46-1717
    • Kumamoto
      • Kumamoto, Kumamoto, Japan, 860-8556
        • Recruiting
        • Kumamoto University Hospital
        • Contact:
          • Yawara Kawano, Site 0198
          • Phone Number: +81-96-373-5156
    • Shizuoka
      • Sunto-gun, Shizuoka, Japan, 411-8777
        • Recruiting
        • Shizuoka Cancer Center
        • Contact:
          • Takashi Ikeda, Site 0130
          • Phone Number: 055-989-5222
  • Mexico
      • Mexico City, Mexico, 04100
        • Withdrawn
        • Local Institution - 0107
    • Mexico City
      • Mexico City, Mexico City, Mexico, 14080
        • Withdrawn
        • Local Institution - 0127
    • Nuevo León
      • Monterrey, Nuevo León, Mexico, 64460
        • Recruiting
        • "Universidad Autonoma de Nuevo Leon - Hospital Universitario ""Dr. Jose Eleuterio Gonzalez"""
        • Contact:
          • David Gomez-Almaguer, Site 0283
          • Phone Number: 52558183486136
    • State of Mexico
      • Toluca, State of Mexico, Mexico, 50090
        • Recruiting
        • Phylasis Clinicas Research S.de R.L. de C.V. (PCR)-Toluca
        • Contact:
          • Carolina Garcia Castillo, Site 0146
          • Phone Number: +5215543460148
  • Netherlands
      • Almere Stad, Netherlands, 1315 RA
        • Active, not recruiting
        • Local Institution - 0325
      • Dordrecht, Netherlands, 3300 AK
        • Recruiting
        • Albert Schweitzer Hospital - Locatie Dordwijk
        • Contact:
          • Mark-David Levin, Site 0070
          • Phone Number: 0031 0786523377
    • North Holland
      • Amsterdam, North Holland, Netherlands, 1081 HV
        • Recruiting
        • VU University Medical Center
        • Contact:
          • Niels Van de Donk, Site 0129
          • Phone Number: +31204442601
  • Poland
      • Bydgoszcz, Poland, 85-048
        • Not yet recruiting
        • Local Institution - 0327
        • Contact:
          • Site 0327
      • Gliwice, Poland, 44-102
        • Recruiting
        • Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology Gliwice Branch
        • Contact:
          • Sebastian Giebel, Site 0252
          • Phone Number: 48322788523
      • Katowice, Poland, 40-519
        • Recruiting
        • Pratia Onkologia Katowice
        • Contact:
          • Sebastian Grosicki, Site 0039
          • Phone Number: +48600388282
      • Lublin, Poland, 20-134
        • Recruiting
        • Office of Dr n. Med. Wojciech Legiec
        • Contact:
          • Wojciech Legiec, Site 0044
          • Phone Number: 48502074194
      • Warsaw, Poland, 02-781
        • Recruiting
        • Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy
        • Contact:
          • Joanna Romejko-Jarosinska, Site 0119
          • Phone Number: 48225462448
    • Kuyavian-Pomeranian Voivodeship
      • Bydgoszcz, Kuyavian-Pomeranian Voivodeship, Poland, 85-168
        • Recruiting
        • Szpital Uniwersytecki Nr. 2 im Dr. Jana Biziela w Bydgoszczy
        • Contact:
          • Jaroslaw Czyz, Site 0149
          • Phone Number: 508508810
    • Pomeranian Voivodeship
      • Gdansk, Pomeranian Voivodeship, Poland, 80-211
        • Recruiting
        • Uniwersyteckie Centrum Kliniczne
        • Contact:
          • Agata Tyczynska, Site 0195
          • Phone Number: 501348850
    • Łódź Voivodeship
      • Lodz, Łódź Voivodeship, Poland, 93-510
        • Recruiting
        • Wojewódzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im. M. Kopernika w Łodzi
        • Contact:
          • Agnieszka Wierzbowska, Site 0059
  • Portugal
      • Braga, Portugal, 4710-243
        • Recruiting
        • Unidade Local de Saude Braga
        • Contact:
          • Herlander Marques, Site 0023
          • Phone Number: +00351253027249
      • Coimbra, Portugal, 3000-075
        • Recruiting
        • Unidade Local de Saúde de Coimbra, EPE - Hospitais da Universidade de Coimbra
        • Contact:
          • Catarina Isabel Batista Geraldes dos Santos, Site 0151
          • Phone Number: +351239400430
      • Porto, Portugal, 4200-072
        • Recruiting
        • Instituto Português Oncologia do Porto Francisco Gentil, EPE
        • Contact:
          • Catarina Campos Costa Moreira, Site 0126
          • Phone Number: +3512250840007110
  • Romania
      • Cluj-Napoca, Romania, 400015
        • Recruiting
        • "Institutul Oncologic ""Prof. Dr. Ion Chiricuţă"" Cluj Napoca"
        • Contact:
          • Ioana Rus, Site 0072
          • Phone Number: 0040741416198
    • B
      • Bucharest, B, Romania, 022328
        • Recruiting
        • Institutul Clinic Fundeni
        • Contact:
          • Sorina Badelita, Site 0117
          • Phone Number: 0040724238956
    • Dolj
      • Craiova, Dolj, Romania, 200143
        • Recruiting
        • Spitalul Clinic Municipal Filantropia Craiova
        • Contact:
          • Luminita Ocroteala, Site 0043
          • Phone Number: 0040735439439
    • IS
      • Iași, IS, Romania, 700483
        • Recruiting
        • Institutul Regional de Oncologie Iasi
        • Contact:
          • Catalin Danaila, Site 0224
          • Phone Number: +40722565781
    • Jud. Cluj
      • Cluj-Napoca, Jud. Cluj, Romania, 400015
        • Recruiting
        • "Institutul Oncologic ""Prof. Dr. Ion Chiricuţă"" Cluj Napoca"
        • Contact:
          • ANCA VASILACHE, Site 0064
          • Phone Number: 0040745522984
  • Singapore
      • Singapore, Singapore, 169608
        • Recruiting
        • Singapore General Hospital
        • Contact:
          • Yunxin Chen, Site 0187
          • Phone Number: 63214925
      • Singapore, Singapore, 119074
        • Recruiting
        • National University Hospital (S) Pte Ltd
        • Contact:
          • Wee Joo Chng, Site 0138
          • Phone Number: 6567724612
  • South Korea
      • Busan, South Korea, 49241
        • Recruiting
        • Pusan National University Hospital
        • Contact:
          • Ho-Jin Shin, Site 0145
          • Phone Number: 821089371258
      • Goyang-si, South Korea, 410-769
        • Recruiting
        • National Cancer Center
        • Contact:
          • Hyeon Seok Eom, Site 0113
          • Phone Number: 82319201160
      • Seongnam-si, Gyeonggi-do, South Korea, 13620
        • Recruiting
        • Seoul National University Bundang Hospital
        • Contact:
          • Ji Yun Lee, Site 0293
          • Phone Number: +82234103459
      • Seoul, South Korea, 06351
        • Recruiting
        • Samsung Medical Center
        • Contact:
          • Kihyun Kim, Site 0114
          • Phone Number: +821099333456
      • Seoul, South Korea, 03722
        • Recruiting
        • Yonsei University Health System, Severance Hospital
        • Contact:
          • Jin Seok Kim, Site 0295
          • Phone Number: 82222281972
      • Ulsan, South Korea, 44033
        • Recruiting
        • Ulsan University Hospital (UUH)
        • Contact:
          • Jae-Cheol Jo, Site 0225
          • Phone Number: 82522508632
  • Spain
      • Badalona, Spain, 08916
        • Recruiting
        • Hospital Universitari Germans Trias i Pujol
        • Contact:
          • Albert Oriol Rocafiguera, Site 0232
          • Phone Number: 34934978987
      • Madrid, Spain, 28022
        • Recruiting
        • Clínica Universidad de Navarra -Madrid
        • Contact:
          • Paula Rodriguez Otero, Site 0317
          • Phone Number: +0034948254000 0 000
      • Palma de Mallorca, Spain, 07120
        • Recruiting
        • Hospital Universitari Son Espases
        • Contact:
          • Antonia Sampol Mayol, Site 0164
          • Phone Number: 34871206268
      • Pamplona, Spain, 31008
        • Recruiting
        • Clinica Universidad de Navarra
        • Contact:
          • Paula Rodriguez, Site 0163
          • Phone Number: +34948255400x5813
    • B
      • Barcelona, B, Spain, 08036
        • Recruiting
        • Hospital Clinic de Barcelona
        • Contact:
          • Laura Rosinol, Site 0226
          • Phone Number: +34932275428
    • CC
      • Cáceres, CC, Spain, 10003
        • Recruiting
        • Hospital San Pedro De Alcantara
        • Contact:
          • Sara Caceres Hernandez, Site 0169
          • Phone Number: +34648009294
    • Las Palmas
      • Las Palmas de Gran Canaria, Las Palmas, Spain, 35019
        • Recruiting
        • Hospital Universitario de Gran Canaria Doctor Negrín
        • Contact:
          • Alexia Teresa Suarez Cabrera, Site 0172
          • Phone Number: +34928449465
    • MU
      • Murcia, MU, Spain, 30120
        • Recruiting
        • Hospital Universitario Virgen Arrixaca
        • Contact:
          • Valentin Cabanas, Site 0155
    • Principality of Asturias
      • Oviedo, Principality of Asturias, Spain, 33011
        • Recruiting
        • Hospital Universitario Central de Asturias
        • Contact:
          • Angel Ramirez Payer, Site 0166
    • VC
      • Valencia, VC, Spain, 46026
        • Recruiting
        • Hospital Universitari i Politecnic La Fe
        • Contact:
          • Javier DE LA RUBIA COMOS, Site 0174
          • Phone Number: +34961245875
  • Sweden
      • Borås, Sweden, 501 82
        • Recruiting
        • Södra Älvsborgs Sjukhus
        • Contact:
          • Ulf-Henrik Mellqvist, Site 0230
          • Phone Number: +46336161034
      • Uddevalla, Sweden, 451 51
        • Recruiting
        • Vastra Goetalandsregionen - Uddevalla Sjukhus (US)
        • Contact:
          • Dorota Knut-Bojanowska, Site 0291
          • Phone Number: +46104354701
    • BD
      • Luleå, BD, Sweden, 971 80
        • Withdrawn
        • Local Institution - 0171
  • Switzerland
      • Aarau, Switzerland, 5001
        • Withdrawn
        • Local Institution - 0168
  • Taiwan
      • Kaohsiung City, Taiwan, 82445
        • Recruiting
        • E-Da Cancer Hospital
        • Contact:
          • Sung-Nan Pei, Site 0175
      • Kaohsiung City, Taiwan, 83301
        • Recruiting
        • Chang Gung Medical Foundation - Kaohsiung Branch
        • Contact:
          • Ming-Chun Ma, Site 0153
          • Phone Number: +886773171233267
      • New Taipei City, Taiwan, 220
        • Recruiting
        • Far Eastern Memorial Hospital
        • Contact:
          • Yuan-Bin Yu, Site 0159
          • Phone Number: +886228757529 0 000
      • Tainan, Taiwan, 704
        • Recruiting
        • National Cheng Kung University Hospital
        • Contact:
          • Tsai-Yun Chen, Site 0165
          • Phone Number: 886623535354596
      • Taipei, Taiwan, 10002
        • Recruiting
        • National Taiwan University Hospital
        • Contact:
          • Shang-Yi Huang, Site 0292
          • Phone Number: 886223123456X63575
      • Taoyuan District, Taiwan, 333
        • Recruiting
        • Chang Gung Memorial Hospital
        • Contact:
          • Tung-Liang Lin, Site 0289
          • Phone Number: +886975368103
  • Turkey (Türkiye)
      • Ankara, Turkey (Türkiye), 06230
        • Recruiting
        • Ankara Bilkent City Hospital
        • Contact:
          • Guldane Cengiz Seval, Site 0167
          • Phone Number: 905326472564
      • Edirne, Turkey (Türkiye), 22030
        • Recruiting
        • Trakya Üniversitesi Tıp Fakültesi
        • Contact:
          • Ahmet Muzaffer Demir, Site 0052
          • Phone Number: +905335544797
      • Istanbul, Turkey (Türkiye), 34214
        • Withdrawn
        • Local Institution - 0068
      • Istanbul, Turkey (Türkiye), 34381
        • Recruiting
        • T.C. Istanbul Bilim Universitesi - lstanbul Florence Nightingale Hastanesi
        • Contact:
          • Omur Gokmen Sevindik, Site 0309
          • Phone Number: +05437870708
      • Izmir, Turkey (Türkiye), 35100
        • Recruiting
        • Ege Universitesi Tip Fakultesi Hastanesi (Ege University Medical Faculty Hospital)
        • Contact:
          • Filiz Vural, Site 0158
      • Izmir, Turkey (Türkiye), 35575
        • Not yet recruiting
        • Local Institution - 0073
        • Contact:
          • Site 0073
      • Kayseri, Turkey (Türkiye), 38039
        • Recruiting
        • Erciyes Üniversitesi Tıp Fakültesi
        • Contact:
          • Gulsah akyol, Site 0024
          • Phone Number: +905056376776
      • Yenimahalle, Turkey (Türkiye), 06200
        • Recruiting
        • Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastırma Hastanesi
        • Contact:
          • Fevzi Altuntas, Site 0032
          • Phone Number: 903123360909-7215
      • Çankaya, Turkey (Türkiye), 06680
        • Recruiting
        • Liv Hospital Ankara
        • Contact:
          • Meral Beksac, Site 0287
          • Phone Number: 00905326347027
  • United Kingdom
      • Edinburgh, United Kingdom, EH4 2XU
        • Recruiting
        • NHS Lothian - Western General Hospital
        • Contact:
          • Neill Storrar, Site 0160
          • Phone Number: 01315372595
      • London, United Kingdom, W1G 6AF
        • Recruiting
        • Barts Health NHS Trust - St Bartholomew's Hospital
        • Contact:
          • Simon Hallam, Site 0025
          • Phone Number: +02034655351
      • Oxford, United Kingdom, OX4 6LB
        • Recruiting
        • GenesisCare-Oxford
        • Contact:
          • Karthik Ramasamy, Site 0029
          • Phone Number: +4401782674844
    • ABD
      • Aberdeen, ABD, United Kingdom, AB25 2ZN
        • Recruiting
        • NHS Grampian - Aberdeen Royal Infirmary
        • Contact:
          • Stephanie Stone, Site 0173
          • Phone Number: +4401224553394
    • Berkshire
      • Windsor, Berkshire, United Kingdom, SL4 3HD
        • Recruiting
        • GenesisCare -Windosr
        • Contact:
          • Pratap Neelakantan, Site 0161
    • DBY
      • Derby, DBY, United Kingdom, DE22 3NE
        • Recruiting
        • University Hospitals of Derby and Burton NHS Foundation Trust - Royal Derby Hospital
        • Contact:
          • Firas Al-Kaisi, Site 0156
          • Phone Number: 01332787971
    • DOR
      • Bournemouth, DOR, United Kingdom, BH7 7DW
        • Recruiting
        • University Hospitals Dorset NHS Foundation Trust (UHD) - Royal Bournemouth Hospital (RBH)
        • Contact:
          • Rachel Hall, Site 0162
          • Phone Number: +4403000194790
    • HAM
      • Portsmouth, HAM, United Kingdom, PO6 3LY
        • Recruiting
        • Portsmouth Hospitals NHS Trust - Queen Alexandra Hospital
        • Contact:
          • Edward Belsham, Site 0284
          • Phone Number: +4402392286311
    • Staffordshire
      • Stoke-on-Trent, Staffordshire, United Kingdom, ST4 6QG
        • Recruiting
        • University Hospitals of North Midlands NHS Trust (UHNM) - Royal Stoke University Hospital
        • Contact:
          • Kamaraj Karunanithi, Site 0154
          • Phone Number: +447971085953
  • United States
    • Colorado
      • Aurora, Colorado, United States, 80012-5405
        • Recruiting
        • Rocky Mountain Cancer Centers
        • Contact:
          • John Burke, Site 0202
          • Phone Number: 303-925-0700
    • Florida
      • Jacksonville, Florida, United States, 32224
        • Recruiting
        • Mayo Clinic Florida
        • Contact:
          • Sikander Ailawadhi, Site 0007
          • Phone Number: 904-953-0853
      • Tampa, Florida, United States, 33606
        • Recruiting
        • Tampa General Hospital
        • Contact:
          • Ivan Borrello, Site 0308
          • Phone Number: 410-955-4967
      • Tampa, Florida, United States, 33612-9416
        • Recruiting
        • H. Lee Moffitt Cancer Center & Research Institute
        • Contact:
          • Melissa Alsina, Site 0192
          • Phone Number: 813-745-7202
      • Weston, Florida, United States, 33331-3609
        • Recruiting
        • Cleveland Clinic
        • Contact:
          • Chakra Chaulagain, Site 0003
          • Phone Number: 954-487-2124
    • Georgia
      • Athens, Georgia, United States, 30607-1465
        • Recruiting
        • University Cancer Blood Ctr
        • Contact:
          • Charles Bodine, Site 0019
      • Atlanta, Georgia, United States, 30322-1013
        • Recruiting
        • The Winship Cancer Institute of Emory University
        • Contact:
          • Sagar Lonial, Site 0018
          • Phone Number: 404-778-1900
      • Augusta, Georgia, United States, 30912
        • Recruiting
        • Augusta University - Georgia Cancer Center
        • Contact:
          • Amany Keruakous, Site 0021
          • Phone Number: 706-721-2505
    • Illinois
      • Chicago, Illinois, United States, 60637-1426
        • Recruiting
        • The University of Chicago Medical Center - Duchossois Center for Advanced Medicine
        • Contact:
          • Benjamin Derman, Site 0237
          • Phone Number: 847-275-8131
    • Kansas
      • Westwood, Kansas, United States, 66205-2003
        • Recruiting
        • University of Kansas Cancer Center - The Richard and Annette Bloch Cancer Care Pavilion
        • Contact:
          • Al-Ola Abdallah, Site 0015
          • Phone Number: 918-261-6196
    • Maryland
      • Clinton, Maryland, United States, 20735-4230
        • Recruiting
        • Maryland Oncology Hematology, PA- Clinton
        • Contact:
          • Jose Mendoza, Site 0205
          • Phone Number: 323-357-7100
    • Massachusetts
      • Worcester, Massachusetts, United States, 01655
        • Recruiting
        • UMass Memorial Medical Center
        • Contact:
          • Muthalagu Ramanathan, Site 0279
          • Phone Number: 774-442-3903
    • Michigan
      • Ann Arbor, Michigan, United States, 48109-5000
        • Recruiting
        • University of Michigan - Rogel Cancer Center
        • Contact:
          • Matthew Pianko, Site 0001
          • Phone Number: 734-647-0118
      • Detroit, Michigan, United States, 48202-2610
        • Recruiting
        • Henry Ford Health System - The Henry Ford Cancer Institute (HFCI) - Detroit
        • Contact:
          • Philip Kuriakose, Site 0257
          • Phone Number: 313-916-1901
      • Grand Rapids, Michigan, United States, 49503
        • Recruiting
        • Cancer & Hematology Centers of Western Michigan (CHCWM)
        • Contact:
          • Andrew Sochacki, Site 0296
          • Phone Number: 616-954-5554
    • Minnesota
      • Rochester, Minnesota, United States, 55905
        • Recruiting
        • Mayo Clinic Cancer Center (MCCC) - Rochester
        • Contact:
          • Prashant Kapoor, Site 0303
          • Phone Number: 507-284-0969
    • Mississippi
      • Hattiesburg, Mississippi, United States, 39401
        • Recruiting
        • Hattiesburg Clinic - Hematology & Oncology
        • Contact:
          • John Hrom, Site 0207
          • Phone Number: 601-261-1700
    • New Jersey
      • Morristown, New Jersey, United States, 07960
        • Recruiting
        • Morristown Medical Center
        • Contact:
          • Mohamad Cherry, Site 0191
          • Phone Number: 973-971-7906
    • New York
      • Brooklyn, New York, United States, 11220-3313
        • Not yet recruiting
        • Local Institution - 0328
        • Contact:
          • Site 0328
      • Mineola, New York, United States, 11501
        • Recruiting
        • Perlmutter Cancer Center at NYU Langone Hematology Oncology Associates-Mineola
        • Contact:
          • Gareth Morgan, Site 0288
      • New York, New York, United States, 10032-3729
        • Recruiting
        • Columbia University Medical Center - Herbert Irving Pavilion Location
        • Contact:
          • Divaya Bhutani, Site 0020
      • New York, New York, United States, 10016-6402
        • Recruiting
        • NYU Langone Health
        • Contact:
          • Gareth Morgan, Site 0180
      • Westbury, New York, United States, 11590
        • Recruiting
        • Clinical Research Alliance
        • Contact:
          • James D'Olimpio, Site 0274
          • Phone Number: 646-872-8630
    • North Carolina
      • Charlotte, North Carolina, United States, 28204
        • Recruiting
        • Levine Cancer Institute
        • Contact:
          • Leon Bernal-Mizrachi, Site 0331
          • Phone Number: 678-787-7893
      • Charlotte, North Carolina, United States, 28803-2493
        • Recruiting
        • Novant Health Cancer Institute - Elizabeth
        • Contact:
          • Raymond Thertulien, Site 0005
          • Phone Number: 646-708-2544
      • Durham, North Carolina, United States, 27705-3976
        • Recruiting
        • Duke University Hospital
        • Contact:
          • Cristina Gasparetto, Site 0281
          • Phone Number: 919-668-8222
      • Winston-Salem, North Carolina, United States, 27103
        • Recruiting
        • Novant Health Cancer Institute Hematology - Forsyth
        • Contact:
          • Raymond Thertulien, Site 0286
          • Phone Number: 646-708-2544
      • Winston-Salem, North Carolina, United States, 27157
        • Recruiting
        • Wake Forest University Baptist Medical Center (WFUBMC) - Comprehensive Cancer Center
        • Contact:
          • Leon Bernal-Mizrachi, Site 0322
          • Phone Number: 678-787-7893
    • Ohio
      • Cincinnati, Ohio, United States, 45236-2725
        • Recruiting
        • Oncology Hematology Care, Inc. - Cincinnati - Galbraith Rd
        • Contact:
          • Kruti Patel, Site 0238
          • Phone Number: 888-961-4156
      • Cleveland, Ohio, United States, 44195
        • Recruiting
        • Cleveland Clinic
        • Contact:
          • Sandra Mazzoni, Site 0002
          • Phone Number: 216-445-2025
      • Cleveland, Ohio, United States, 44111
        • Recruiting
        • Cleveland Clinic - Fairview Hospital - Cancer Center (Moll Cancer Center)
        • Contact:
          • Sandra Mazzoni, Site 0299
          • Phone Number: 216-445-2025
      • Kansas, Ohio, United States, 64132
        • Recruiting
        • Midwest Oncology Associates - Kansas City
        • Contact:
          • Anis Toumeh, Site 0017
      • Mayfield Heights, Ohio, United States, 44124
        • Recruiting
        • Cleveland Clinic - Hillcrest Hospital - Hillcrest Cancer Center
        • Contact:
          • Sandra Mazzoni, Site 0301
          • Phone Number: 216-445-2025
      • Toledo, Ohio, United States, 43623
        • Completed
        • Local Institution - 0013
      • Wooster, Ohio, United States, 44691
        • Recruiting
        • Wooster Milltown Specialty and Surgery Center
        • Contact:
          • Sandra Mazzoni, Site 0300
          • Phone Number: 216-445-2025
    • Oregon
      • Eugene, Oregon, United States, 97401
        • Recruiting
        • Willamette Valley Cancer Institute
        • Contact:
          • Christopher Yasenchak, Site 0203
          • Phone Number: 541-988-7932
    • Pennsylvania
      • Philadelphia, Pennsylvania, United States, 19107
        • Recruiting
        • Thomas Jefferson University Hospital
        • Contact:
          • Adam Binder, Site 0012
      • Philadelphia, Pennsylvania, United States, 19111-2433
        • Recruiting
        • Fox Chase Cancer Center - Jeanes Campus
        • Contact:
          • Asya Varshavsky-Yanovsky, Site 0011
      • Pittsburgh, Pennsylvania, United States, 15232
        • Recruiting
        • University of Pittsburgh - Hillman Cancer Center
        • Contact:
          • Kathleen Dorritie, Site 0253
          • Phone Number: 412-647-0864
    • Tennessee
      • Germantown, Tennessee, United States, 38138-1762
        • Recruiting
        • West Cancer Center
        • Contact:
          • Jason Chandler, Site 0294
          • Phone Number: 901-683-0055
      • Nashville, Tennessee, United States, 37203-1625
        • Recruiting
        • Tennessee Oncology
        • Contact:
          • Jesus Berdeja, Site 0004
          • Phone Number: 615-329-0570
    • Texas
      • Dallas, Texas, United States, 75246
        • Recruiting
        • Texas Oncology - Baylor Charles A. Sammons Cancer Center
        • Contact:
          • Houston Holmes, Site 0193
          • Phone Number: 214-584-3402
      • Dallas, Texas, United States, 75390-0001
        • Recruiting
        • UT Southwestern-Harold C. Simmons Cancer Center
        • Contact:
          • Larry Anderson, Site 0009
          • Phone Number: 214-648-5906
      • Houston, Texas, United States, 77030-4000
        • Recruiting
        • University of Texas MD Anderson Cancer Center
        • Contact:
          • Oren Pasvolsky, Site 0006
          • Phone Number: 832-728-1403

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria

  • Confirmed diagnosis of symptomatic multiple myeloma (MM).
  • Eastern Cooperative Oncology Group performance status (ECOG) score of 0, 1, or 2.
  • Received 3 to 6 cycles of an induction therapy that includes a proteasome inhibitor (PI) and immunomodulatory (IMiD) [eg, bortezomib thalidomide and dexamethasone (VTd), lenalidomide, bortezomib and dexamethasone (RVd)] with or without a CD38 monoclonal antibody, daratumumab + bortezomib/thalidomide/dexamethasone [D-VTd] and daratumumab + bortezomib/ lenalidomide/dexamethasone [D-VRd]), or VCd / daratumumab + bortezomib/cyclophosphamide/dexamethasone [D-VCd], and followed by a single or tandem autologous stem cell transplantation (ASCT). Post-stem cell transplant consolidation is permitted.
  • Participants within 12 months (single transplant) or 15 months (tandem transplant) from initiation of induction therapy who achieved at least a partial response (PR) after autologous stem cell transplantation (ASCT) with or without consolidation, according to International Myeloma Working Group (IMWG 2016) criteria.

Exclusion Criteria

  • Progressive disease or clinical relapse (as defined by IMWG response criteria) following ASCT with or without consolidation or is not responsive to primary therapy.
  • Smoldering myeloma, solitary plasmacytoma or nonsecretory myeloma.
  • Known central nervous system/meningeal involvement of MM.
  • Prior history of malignancies, other than MM, unless the participant has been free of the disease for ≥ 5 years.
  • Other protocol-defined Inclusion/Exclusion criteria apply.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Arm A1: Iberdomide Dose 1
Drug: Iberdomide
Specified dose on specified days
Other Names:
  • CC-220
  • BMS-986382
Experimental: Arm A2: Iberdomide Dose 2
Drug: Iberdomide
Specified dose on specified days
Other Names:
  • CC-220
  • BMS-986382
Experimental: Arm A3: Iberdomide Dose 3
Drug: Iberdomide
Specified dose on specified days
Other Names:
  • CC-220
  • BMS-986382
Active Comparator: Arm B: Lenalidomide
Drug: Lenalidomide
Specified dose on specified days
Other Names:
  • Revlimid®

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Progression-free survival (PFS)
Time Frame: Up to 6 years
Up to 6 years

Secondary Outcome Measures

Outcome Measure
Time Frame
Achieving minimal residual disease (MRD) negativity in participants with complete response (CR) or better at 12 (± 3) months of maintenance treatment
Time Frame: Up to 6 years
Up to 6 years
Overall Survival
Time Frame: Up to 12 years
Up to 12 years
Recommended iberdomide dose for Stage 2
Time Frame: Up to 1 year
Up to 1 year
Area under the iberdomide plasma concentration-time curve from time zero to tau
Time Frame: Up to 1 year
Up to 1 year
Area under the iberdomide plasma concentration-time curve within a dosing interval AUC (TAU)
Time Frame: Up to 1 year
Up to 1 year
Maximum iberdomide concentration (Cmax)
Time Frame: Up to 1 year
Up to 1 year
Time to maximum iberdomide plasma concentration (Tmax)
Time Frame: Up to 1 year
Up to 1 year
Number of participants with adverse events (AEs)
Time Frame: Up to 6 years
Up to 6 years
Progression-free survival on next line of treatment (PFS2)
Time Frame: Up to 6 years
Up to 6 years
Achieving MRD negativity in participants with CR or better at any time after the date of randomization
Time Frame: Up to 6 years
Up to 6 years
Conversion from MRD positive to MRD negative in participants with CR or better
Time Frame: Up to 6 years
Up to 6 years
Time to progression (TTP)
Time Frame: Up to 6 years
Up to 6 years
Time to next treatment (TTNT)
Time Frame: Up to 6 years
Up to 6 years
Best response achieved prior to progressive disease (PD)
Time Frame: Up to 6 years
Up to 6 years
Patient-reported health-related quality of life (HRQoL) outcomes and multiple myeloma-related symptoms as measured by the European Organization for Research and Treatment of Cancer [EORTC] Quality of Life C30 questionnaire (QLQ-C30)
Time Frame: Up to 6 years
Up to 6 years
Patient-reported HRQoL outcomes and multiple myeloma-related symptoms as measured by the EORTC Quality of Life Multiple Myeloma Module (QLQ-MY20)
Time Frame: Up to 6 years
Up to 6 years
Achievement of CR or better and maintaining MRD-negative status in 2 bone marrow aspirate assessments that are a minimum of 1 year apart, without any examination showing MRD positive status in between assessments
Time Frame: Up to 6 years
Up to 6 years

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Bristol-Myers Squibb

Investigators

  • Study Director: Bristol-Myers Squibb, Bristol-Myers Squibb

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

Helpful Links

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

June 22, 2023

Primary Completion (Estimated)

March 15, 2029

Study Completion (Estimated)

January 1, 2036

Study Registration Dates

First Submitted

April 11, 2023

First Submitted That Met QC Criteria

April 11, 2023

First Posted (Actual)

April 24, 2023

Study Record Updates

Last Update Posted (Actual)

March 13, 2026

Last Update Submitted That Met QC Criteria

March 12, 2026

Last Verified

March 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • IM048-022
  • U1111-1280-9492 (Other Identifier: WHO)
  • 2022-501515-14-00 (Other Identifier: EU CTR)

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Plan Description

BMS will provide access to individual anonymized participant data upon request from qualified researchers, and subject to certain criteria. Additional information regarding Bristol Myer Squibb's data sharing policy and process can be found at https://www.bms.com/researchers-and-partners/clinical-trials-and-research.html

IPD Sharing Time Frame

See Plan Description

IPD Sharing Access Criteria

See Plan Description

IPD Sharing Supporting Information Type

  • STUDY_PROTOCOL
  • SAP
  • CSR

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

Yes

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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