Median Nerve Function During Phalen's Test

Electrophysiological Assessment of the Median Nerve During the Phalen's Test for Carpal Tunnel Syndrome

This study will use electromyography and nerve conduction studies to evaluate median nerve function during the Phalen's wrist flexion test in different wrist positions.

Study Overview

• Status: Recruiting
• Conditions: Carpal Tunnel Syndrome
• Intervention / Treatment: Diagnostic test: Phalen's wrist flexion test

Detailed Description

The Phalen's test is commonly used to assess carpal tunnel syndrome. However, it is unclear which wrist position during this test best isolates median nerve function. This study will measure thenar muscle activation and median nerve conduction in 30 healthy participants performing the Phalen's test. Different wrist flexion angles will be evaluated to determine which position optimally targets the median nerve. Results may enhance utilization of the Phalen's test in clinical practice and research.

• Study Type: Observational
• Enrollment (Estimated): 30

Contacts and Locations

• Study Contact: Name: Mohamed M ElMeligie, Ph.d; Phone Number: +201064442032; Email: mohamed.elmeligie@acu.edu.eg

Study Locations

• Egypt
  • Giza
    • Al Ḩayy Ath Thāmin, Giza, Egypt, 3221405
      • Recruiting
      • Outpatient clinic of faculty of physical therapy, Ahram Canadian University
      • Contact: Mohamed M ElMeligie, Ph.d; Phone Number: 01064442032; Email: mohamed.elmeligie@acu.edu.eg

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: Yes

• Sampling Method: Non-Probability Sample

Study Population

Healthy men and women aged 18-45 recruited from the local community.

Description

Inclusion Criteria:

• Healthy adults aged 18-45 years
• No history of hand/wrist disorders

Exclusion Criteria:

• Contraindications to EMG or NCV
• Neurological or muscular disorders

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Healthy Adults; 30 healthy adult participants aged 18-45 years performing the Phalen's wrist flexion test	Diagnostic test: Phalen's wrist flexion test; The Phalen's test will be performed at different wrist flexion angles from 0 to 90 degrees.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Thenar Muscle Activation	Mean EMG activity of the thenar muscles during the Phalen's test at different wrist angles. Measured in microvolts (μV).	Baseline
Median Nerve Conduction Velocity during Phalen's Test	Median nerve conduction velocity (measured in meters per second, m/s) assessed using surface electrodes at the wrist and elbow during the Phalen's test wrist flexion maneuver. Measured bilaterally at each wrist flexion angle during a single study visit.	Baseline
Median Nerve Distal Latency during Phalen's Test	Median nerve distal latency (measured in milliseconds, ms) assessed using surface electrodes over the abductor pollicis brevis and stimulating the median nerve at the wrist during the Phalen's test. Measured bilaterally at each wrist flexion angle during a single study visit.	Baseline

Collaborators and Investigators

• Sponsor: Ahram Canadian University
• Investigators: Study Chair: Amal Fawzy, Ph.d, Faculty of Physical Therapy, Ahram Canadian University

Study record dates

Study Major Dates

• Study Start (Estimated): July 25, 2023
• Primary Completion (Estimated): November 25, 2023
• Study Completion (Estimated): December 15, 2023

Study Registration Dates

• First Submitted: July 20, 2023
• First Submitted That Met QC Criteria: July 20, 2023
• First Posted (Actual): July 28, 2023

Study Record Updates

• Last Update Posted (Actual): July 28, 2023
• Last Update Submitted That Met QC Criteria: July 20, 2023
• Last Verified: July 1, 2023

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Pathologic Processes; Nervous System Diseases; Wounds and Injuries; Disease; Neuromuscular Diseases; Mononeuropathies; Peripheral Nervous System Diseases; Median Neuropathy; Nerve Compression Syndromes; Cumulative Trauma Disorders; Sprains and Strains; Syndrome; Carpal Tunnel Syndrome
• Other Study ID Numbers: OT-PT-001

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No