The Effect Of Proprioceptive Neuromuscular Facilitation Techniqueson in Patients With Multiple Sclerosis

October 20, 2023 updated by: Nilay Comuk Balci

The Effect Of Proprioceptive Neuromuscular Facilitation Techniqueson Pain, Motor Functions, Fatique and Health Related Quality of Life in Patients With Multiple Sclerosis: A Randomized, Single-blind Study.

The aim of this study is to examine the effects of PNF techniques on pain, motor function, fatigue and quality of life.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

44

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey
      • Samsun, Turkey, 55270
        • Ondokuz Mayıs University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • a clinical diagnosis of Relapsing-Remitting MS (RRMS) as defined by McDonald criteria
  • 18-65 years of age
  • an Expanded Disability Status Scale (EDSS) score < 4
  • relapse-free for the last 3 months
  • cognitive impairment that was defined with mini mental test.

Exclusion Criteria:

  • a history of different neurological diseases
  • having any contraindication for exercise
  • having orthopedic, vision, hearing, or perception problems.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Sham Comparator: Control Group
Other: Control Group
Exercise training
Experimental: PNF Group
Other: PNF Group
Exercise training and PNF training

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Visual Analogue Scale (VAS)
Time Frame: through study completion, an average of 1 year
Pain
through study completion, an average of 1 year
Multiple Sclerosis Quality of Life-54 (MSQoL-54)
Time Frame: through study completion, an average of 1 year
Quality of Life
through study completion, an average of 1 year
Fatigue Severity Scale and Fatigue Impact Scale (FIS)
Time Frame: through study completion, an average of 1 year
Fatigue
through study completion, an average of 1 year
Timed Up and Go (TUG)
Time Frame: through study completion, an average of 1 year
Mobility and Balance
through study completion, an average of 1 year
The Six-Minute Walk Test (6-MWT)
Time Frame: through study completion, an average of 1 year
Functionality
through study completion, an average of 1 year
Hand Dexterity
Time Frame: through study completion, an average of 1 year
Hand Dexterity
through study completion, an average of 1 year

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Nilay Comuk Balci

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

November 1, 2021

Primary Completion (Actual)

November 1, 2022

Study Completion (Actual)

November 1, 2022

Study Registration Dates

First Submitted

October 16, 2023

First Submitted That Met QC Criteria

October 20, 2023

First Posted (Actual)

October 26, 2023

Study Record Updates

Last Update Posted (Actual)

October 26, 2023

Last Update Submitted That Met QC Criteria

October 20, 2023

Last Verified

October 1, 2023

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2021/413

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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