Long LIMA Patch on Left Anterior Descending Coronary Artery in CABG
Long Left Internal Mammary Artery Patch on Left Anterior Descending Coronary Artery in Coronary Artery Bypass Grafting
Study Overview
Detailed Description
It is well-known that coronary artery bypass graft (CABG) surgery significantly increases life expectancy, so complete myocardial revascularization should be the main goal of the surgical intervention process (1). During coronary artery bypass surgery, the surgeon removes a piece of blood vessel from the leg, chest, arm, or belly. Then, the surgeon uses that piece of blood vessel (called a "graft") to reroute blood around the blocked artery. The surgery is called "bypass surgery" because it bypasses the blockage Complete revascularization in CABG is crucial to improve early and late outcomes after surgery. Conventional procedures cannot achieve satisfactory results in severely diseased left anterior descending coronary artery .
Endarterectomy for severely atherosclerotic coronary artery disease (CAD) has a higher surgical risk and poor late outcomes . Reconstruction of diffusely diseased LAD with left internal mammary artery (LIMA) on-lay patch has less risk and complications than endarterectomy technique Ogus and colleagues used LIMA on-lay patches for the reconstruction of LAD based on the superior patency rate of the LIMA over other techniques which are more time-consuming. According to Lüscher and colleagues , the advantage of LIMA on-lay patch is to provide better vasomotor function and adjust the flow rate in proportion to the distal runoff.
In the recent study by Rezk etal., reported that , LAD reconstruction with a LIMA patch could have a better short-term outcome than other techniques as saphenous vein patch without an endarterectomy for a diffusely diseased left anterior descending coronary artery.
Study Type
Enrollment (Estimated)
Contacts and Locations
Study Contact
- Name: Marwan Ahmed Mohamed, resident doctor
- Phone Number: 01282636415
- Email: marwanahmed1997y2@gmail.com
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Adult
- Older Adult
Accepts Healthy Volunteers
Sampling Method
Study Population
Description
Inclusion Criteria:
- Any patient male,( or female) and his(or her) age from 30-90 years have Ischemic Heart Disease for CABG with diffusely diseased LAD.
Exclusion Criteria:
- Any patient performed open heart surgery before
Study Plan
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
assess the effect of LIMA patch as a method for the reconstruction on diffusely diseased LAD in the early and midterm outcomes
Time Frame: first week postoperative
|
asses postoperative new arrhythmia//use of Inotropes// second session of surgery
|
first week postoperative
|
Collaborators and Investigators
Sponsor
Investigators
- Study Chair: Sameh Abdelrahman, professor, Professor of Cardiothoracic surgery
- Principal Investigator: Ahmed Mohamed Taha, professor, Professor of Cardiothoracic surgery
- Study Director: Mohammed Hasan Osman, professor, Professor of General surgery Maxillofacial surgery
Publications and helpful links
General Publications
- Todorov IP, Todorova ZP, Nikolov DP. Angioplasty balloon occlusion of LIMA graft in reoperations of patients with prosthetic valve endocarditis and patent LIMA-LAD graft. Kardiochir Torakochirurgia Pol. 2022 Dec;19(4):199-204. doi: 10.5114/kitp.2022.122089. Epub 2022 Dec 24.
- Yang T, Yuan X, Li B, Zhao S, Sun H, Lu M. Long-term outcomes after coronary artery bypass graft with or without surgical ventricular reconstruction in patients with severe left ventricular dysfunction. J Thorac Dis. 2023 Apr 28;15(4):1627-1639. doi: 10.21037/jtd-22-1214. Epub 2023 Mar 23.
Study record dates
Study Major Dates
Study Start (Estimated)
Primary Completion (Estimated)
Study Completion (Estimated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimated)
Study Record Updates
Last Update Posted (Estimated)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
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