Effect of Anti-aging Therapy on Fitness Enhancement in Perimenopausal Women

Aging is an important fact to consider from the woman's health perspective. One of the most significant stages of aging is menopause, in which involves physical, psychological, and social changes in life

Study Overview

• Status: Completed
• Conditions: Aging Well
• Intervention / Treatment: Other: aerobic exercises

Detailed Description

This study will be carried on forty perimenopausal women. They were selected randomly from outpatient clinic of El Kaser El-Einy University Hospital, Cairo University, their age ranged from 40 to 50 years.

Group A ( Control group):

It consisted of 20 perimenopausal women. They received anti-aging diet instructions.

Group B ( Experimental group):

It will be consisted of 20 perimenopausal women.They received anti-aging therapy (Aerobic, Flexibility and strengthening exercises) with anti aging diet instructions.

Randomization:

Randomization of sample selection was achieved using closed envelop way. Classification of the sample by simple random way into two groups equal in number, twenty for each group by using forty closed envelop, each twenty envelop contained a name of a group from the two groups (Group A) or (Group B) and asking each woman to choose one envelop from them, each woman attended to the group according the name of the group written in her envelop.

• Study Type: Interventional
• Enrollment (Actual): 40
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Egypt
  • Giza, Egypt, 12662
    • Faculty of physical therapy, Cairo University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

• They complaining from fatigue, hot flushes and irregular period.
• Their Body Mass Index (BMI) between 25 to 30 .
• Their age ranged from 40 to 50 years old.
• The assessment procedures will be conducted on the same time of the day pre/post treatment.

Exclusion Criteria:

• Women with comorbidities such as cardiac disease and chest diseases as pulmonary fibrosis.
• Women received medications that might affect the neuromuscular functions at least three months before or during the study course.
• Women suffered from mental or psychological disorders.
• Women suffered from inflammatory diseases such as rheumatoid arthritis or polymyalgia rheumatic.
• Women complaining from osteoporosis.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Placebo Comparator: control group; Antiaging diet instructions	Other: aerobic exercises; Antiaging diet instruction :Be aware of the amount of calories, Reduce overall fat and sugar intake, Drink at least 10 glasses of water every day in order to remain healthy. d. Eat a variety of complex carbohydrates and vegetables instead of bread, rice, and corn.; Other Names: strengthening exercises; flexibility exercises; anti aging diet instruction
Experimental: intervention group; aerobic exercises: walking :30 min on treadmill 30min at least three times per week for 12 weeks; Muscle strength Exercises:For upper extremity : hand grip exercise, arm flexion exercise ten repetition for each exercise three times per week.Theraband exercises for upper limb exercise ten repetition for each exercise three times per week.; Flexibility Exercise : Curl up exercise and Seat and reach up exercises exercise ten repetition for each exercise three times per week. Lateral flexibility exercises for ten repetition for each exercise three times per week,for 12 weeks and anti aging diet instruction	Other: aerobic exercises; Antiaging diet instruction :Be aware of the amount of calories, Reduce overall fat and sugar intake, Drink at least 10 glasses of water every day in order to remain healthy. d. Eat a variety of complex carbohydrates and vegetables instead of bread, rice, and corn.; Other Names: strengthening exercises; flexibility exercises; anti aging diet instruction

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
6-minute walking test	The 6 Minute Walk Test is a sub-maximal exercise test used to assess aerobic capacity and endurance. The distance covered over a time of 6 minutes is used as the outcome by which to compare changes in performance capacity.	12 weeks
toe touch test	This test measures the flexibility of the lower back and hamstrings, and is a valid measure of this.The toe touch test is a common test of flexibility, and is an easy and quick test to perform. If using the standard testing procedure, there is a lot of published data to use for comparison.	12 weeks
hand held dynamometer	Hand held dynamometer demonstrated an excellent intra- and inter-rater reliability for assessment of isometric lumbar muscles strength of healthy subject at clinical setting as it is simple to use, portable and cost-effective for the precise measurement.	12 weeks
body composition analysis	Body composition is a method of describing what the body is made of. It includes fat, protein, minerals and body water. It also describes weight more accurately than BMI. Body composition analysis can accurately show changes in fat mass, muscle mass, and body fat percentage. This can help validate services	12 weeks

Collaborators and Investigators

• Sponsor: Cairo University
• Investigators: Study Chair: Amel Yousef, Cairo university

Study record dates

Study Major Dates

• Study Start (Actual): January 20, 2024
• Primary Completion (Actual): July 20, 2024
• Study Completion (Actual): July 31, 2024

Study Registration Dates

• First Submitted: January 16, 2024
• First Submitted That Met QC Criteria: January 16, 2024
• First Posted (Actual): January 25, 2024

Study Record Updates

• Last Update Posted (Estimated): October 9, 2024
• Last Update Submitted That Met QC Criteria: October 5, 2024
• Last Verified: October 1, 2024

More Information

Terms related to this study

• Keywords: cardiovascular training; healthy antiaging; premenopausal fitness enchancement; diet instruction
• Other Study ID Numbers: P.T.REC/012/005035

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No