Effect of Cupping Therapy on Nitric Oxide Level in Patients With Cervical Spondylosis (CT)

this study will be conducted to investigate the effect of cupping therapy on the nitric oxide level in patients with cervical spondylosis

Study Overview

• Status: Not yet recruiting
• Conditions: Cervical Spondylosis
• Intervention / Treatment: Other: cupping therapy

Detailed Description

Cupping therapy is one of the oldest alternative medical procedures, along with acupuncture, with more than 3500 years of history to treat pain and various disorders. Cupping induces various biological responses that could be evoked by suction of the skin, About 5 to 10 minutes of cupping causes extravascular blood within the subcutaneous tissue and creates bruise-like marks. Therefore, cupping induces mild damage to a painful part of the body and accelerates healing by evoking the natural healing process. While this hypothesis is acceptable for some people, it might not be enough to change the minds of skeptics since cupping itself has no curative effects. Suppose the healing process after cupping can be accelerated by merging cupping with scientifically proven techniques. In that case, this new form of therapy might help to persuade skeptics of the efficacy of cupping. Integrative medicine, including acupuncture, dry needling, and cupping, is being used increasingly in the United States. evidence regarding their efficacy in the management of musculoskeletal conditions is heterogeneous and subject to several limitations. despite these limitations, acupuncture consistently is more effective than no treatment and is relatively safe. for chronic back pain, it is recommended as a first-line noninvasive therapy. for neck pain, acupuncture provides benefits when it is combined with other treatments. dry needling is similar to acupuncture and frequently is regarded as a form of acupuncture. sixty patients with cervical spondylosis will receive cupping therapy for three months.

• Study Type: Interventional
• Enrollment (Estimated): 60
• Phase: Not Applicable

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

• Patients with (cervical spondylosis) from both sexes.
• Age range (24-60) in chronic stages.
• BMI from20-25 kg/m2.

Exclusion Criteria:

• Renal and hepatic patients.
• Anemia, hepatic disease, and dermatological diseases.
• Morbid obese patients if their BMI exceeds the 25 kg/m2 will be also excluded.
• the patients are taking any medications known to affect the pain level
• The patients have a systemic illness, dermatological problems, skin allergy, local ischemic problems

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: N/A
• Interventional Model: Single Group Assignment
• Masking: None (Open Label)

Number of Arms

1

Arms and Interventions

Participant Group / Arm

Intervention / Treatment

Experimental: cupping therapy; patients with cervical spondylosis will receive cupping therapy one time per month for three months

Other: cupping therapy; All the patients will be asked to be in a sitting position with both feet flat on the floor the cupping group will receive the cupping bloodletting at three acupuncture points (SI15, GB21, LI15) the medium size glass with a diameter of 4cm and a volume of 260ml. Each wet cupping treatment procedure will last about 20 min and will be conducted in five steps.; -Primary sucking; -Scarification 3- Bloodletting 4-Removal 5 -Dressing

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
the nitric oxide level	Spectrophotometer device will be used to measure the level of nitric oxide	up to three months

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
cervical range of motion	electrogoniomter device will be used to assess cervical range of motion	up to three months
pain intensity	visual analogue scale will be used to measure pain intensity. The VAS is a 100-mm horizontal line that may be used to quantify symptoms in a continuous fashion. It is easy to use and requires very little written language. Patients are instructed to indicate the intensity of their pain by marking on a line anchored by "no pain" on the left and "worst imaginable pain" on the right.	up to three months

Collaborators and Investigators

• Sponsor: Shady Abdelsattar Refaat

Study record dates

Study Major Dates

• Study Start (Estimated): February 20, 2024
• Primary Completion (Estimated): May 20, 2024
• Study Completion (Estimated): May 20, 2024

Study Registration Dates

• First Submitted: February 14, 2024
• First Submitted That Met QC Criteria: February 14, 2024
• First Posted (Estimated): February 21, 2024

Study Record Updates

• Last Update Posted (Estimated): February 21, 2024
• Last Update Submitted That Met QC Criteria: February 14, 2024
• Last Verified: February 1, 2024

More Information

Terms related to this study

• Keywords: Cervical Spondylosis; cupping therapy
• Additional Relevant MeSH Terms: Musculoskeletal Diseases; Spinal Diseases; Bone Diseases; Spondylosis
• Other Study ID Numbers: P.T.REC/012/002532

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No