Management of PADIS in Emergency Intensive Care Unit

Management of Pain, Agitation-sedation, Delirium Immobility and Sleep Disruption in Emergency Intensive Care Unit: a Multicenter Cross-sectional Survey

Investigate the prevalence of PADIS in EICU, as well as the awareness and clinical implementation status of medical staff towards PADIS.

The investigators conducted a multicenter cross-sectional survey in mainland China, including a one-day point prevalence investigation and a questionnaire survey. The inclusion criteria encompassed all adult patients admitted to the participating emergency department intensive care units (EDICUs) during the on-site screening, while exclusion criteria comprised patients aged less than 18 years, EDICU stays duration less than 24 hours before the screening, and participation in other concurrent trials. Hospital and nursing records from the 24 hours preceding enrollment were examined to document the assessment rate of pain, agitation-sedation, and delirium. Physicians and nurses on duty 24 hours before the patients' enrollment was invited to complete the questionnaire survey regarding the ICU profiles, professional expertise, assessment and treatment of PAD, early mobilization, and sleep improvement practices.

Study Overview

• Status: Completed
• Conditions: Pain; Delirium; Critical Illness; Agitation, Emergence
• Intervention / Treatment: Behavioral: PADIS assessment

• Study Type: Observational
• Enrollment (Actual): 162

Contacts and Locations

Study Locations

• China
  • Beijing
    • Beijing, Beijing, China, 100070
      • Beijing Tiantan Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Probability Sample

Study Population

All patients admitted to the participating EDICU during the on-site investigation were eligible for enrollment in this study. However, patients meeting the following criteria were excluded: 1) age less than 18 years; 2) EDICU stay duration before the screening was less than 24 hours; 3) enrollment in other concurrent trials.

Description

Inclusion Criteria:

• All patients admitted to the participating EDICU during the on-site investigation

Exclusion Criteria:

• Age less than 18 years;
• EDICU stay duration before the screening was less than 24 hours
• Enrollment in other concurrent trials.

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
EDICU patients; All patients admitted to the participating EDICU during the on-site investigation.	Behavioral: PADIS assessment; Hospital and nursing records from the 24 hours preceding enrollment were examined to document the assessment rate of pain, agitation-sedation, and delirium.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
PADIS assessment rate	24 hours before enrollment

Secondary Outcome Measures

Outcome Measure	Time Frame
Rates of analgesic and sedative administration	24 hours before enrollment
Rate of accidental removal of the catheter during the EICU stay	From the start of the survey day until transfer out of the EDICU or 60 days after the survey day.
EDICU length of stay	From the start of the survey day until transfer out of the EDICU or 60 days after the survey day.
The hospital length of stay	From the start of the survey day until transfer out of the EDICU or 60 days after the survey day.

Collaborators and Investigators

• Sponsor: Capital Medical University
• Collaborators: The First Affiliated Hospital of Anhui Medical University; Fudan University; Beijing Tiantan Hospital; Southwest Hospital, China; The First Affiliated Hospital of Zhengzhou University; Beijing Anzhen Hospital; The First Hospital of Jilin University; Tianjin Medical University General Hospital; The First Hospital of Hebei Medical University; The First Affiliated Hospital of Dalian Medical University; Mianyang Central Hospital; The Second Affiliated Hospital of Hainan Medical University; Affiliated hospital of Guilin medical university,China; The Jiangxi Provincial People's Hospital; General hospital of shenyang military command

Study record dates

Study Major Dates

• Study Start (Actual): June 13, 2021
• Primary Completion (Actual): August 12, 2021
• Study Completion (Actual): August 12, 2021

Study Registration Dates

• First Submitted: March 25, 2024
• First Submitted That Met QC Criteria: March 25, 2024
• First Posted (Actual): April 1, 2024

Study Record Updates

• Last Update Posted (Actual): April 2, 2024
• Last Update Submitted That Met QC Criteria: March 29, 2024
• Last Verified: March 1, 2024

More Information

Terms related to this study

• Keywords: Prevalence; Survey; Practices; Emergency Department Intensive Care Units
• Additional Relevant MeSH Terms: Behavioral Symptoms; Mental Disorders; Pathologic Processes; Nervous System Diseases; Postoperative Complications; Neurologic Manifestations; Confusion; Neurobehavioral Manifestations; Neurocognitive Disorders; Disease Attributes; Dyskinesias; Psychomotor Disorders; Aberrant Motor Behavior in Dementia; Delirium; Emergencies; Psychomotor Agitation; Emergence Delirium; Critical Illness
• Other Study ID Numbers: KY 2020-153-02

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No