Implementation of Apnoea Test for Patients With Suspected Brain Death

Implementation of Apnoea Test for Patients With Suspected Brain Death (IMAPing SUBDEP)

This study consists of a survey created for intensive care physicians regarding their current practice of the implementation of apnoea test for patients with suspected brain death.

Study Overview

• Status: Not yet recruiting
• Conditions: Brain Death

Detailed Description

Although the apnoea test is part of nearly all protocols for determining brain death; implementation significantly differs among intensive care physicians according to national-level acts, national society protocols or local protocols.

This cross-sectional study is based on an international, web-based questionnaire created for intensive care physicians, consisting of 25 questions in English.

The survey will provide a current state of the practice of apnoea testing in patients with suspected brain death. The results can support the determination of future acts to standardize the apnoea test process.

The given answers are anonymous. The e-mail address of the respondent is not recorded. Answers are treated solely for scientific purposes.

• Study Type: Observational
• Enrollment (Estimated): 200

Contacts and Locations

• Study Contact: Name: Bakos Péter; Phone Number: +36207752886; Email: imaping.subdep@gmail.com

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: Yes

• Sampling Method: Non-Probability Sample

Study Population

Any physician working in intensive care can fill the form and participate in the study.

Description

Inclusion Criteria:

• Physicians working in intensive care units

Exclusion Criteria:

-

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Number of apnoea tests	How much apnoea test is required for brain death determination.	last 1 year
Timeframe between apnoea tests	If more than 1 apnoeae test is reuired for brain death determination, how many hours should elapse between the two tests.	last 1 year
Preoxygenation	For how long (in minutes) the patient is preoxygenated before the apnoea test.	last 1 year
Baseline arterial carbon dioxide (CO2) level	What is the required arterial partial CO2 pressure (PaCO2) before apnoea testing, confirmed by arterial blood gas measurement?	Last 1 year

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Detection of possible spontaneous breath movements	To determine if any observation method other than visualisation by the observer is used to determine possible spontaneous breath movements during the apnoea test.	last 1 year
Satisfaction with current practice	Surveying the satisfaction of physicians with current practice regarding the method of the detection of spontaneous breath movements on a 4 grade scale (1 - non-reliable to 4 - very reliable).	last 1 year

Other Outcome Measures

Outcome Measure	Measure Description	Time Frame
Continuous positive airway pressure (CPAP)	If a CPAP system is used during apnoea test, what is the value of positive end-expiratory pressure (PEEP) in H2Ocm.	last 1 year

Collaborators and Investigators

• Sponsor: Kiskunhalas Semmelweis Hospital the Teaching Hospital of the University of Szeged
• Collaborators: Veszprém County Ferenc Csolnoky Hospital

Study record dates

Study Major Dates

• Study Start (Estimated): May 1, 2024
• Primary Completion (Estimated): July 31, 2024
• Study Completion (Estimated): July 31, 2024

Study Registration Dates

• First Submitted: March 27, 2024
• First Submitted That Met QC Criteria: April 8, 2024
• First Posted (Actual): April 11, 2024

Study Record Updates

• Last Update Posted (Actual): May 6, 2024
• Last Update Submitted That Met QC Criteria: May 3, 2024
• Last Verified: May 1, 2024

More Information

Terms related to this study

• Keywords: survey; brain death determination; apnoea test
• Additional Relevant MeSH Terms: Pathologic Processes; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Neurologic Manifestations; Neurobehavioral Manifestations; Unconsciousness; Consciousness Disorders; Coma; Death; Brain Death
• Other Study ID Numbers: IMAPing SUBDEP

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No