Enhancing Care Study in Patients After CABG (OptiCABG)

Enhancing Care in Patients After Coronary Artery Bypass Graft Surgery (CABG)： OptiCABG Study

Review the data of patients who underwent coronary artery bypass grafting (CABG) at the National Center for Cardiovascular Disease, Fuwai Hospital from January 2013 to June 2023 including medical history, head CT scan, and postoperative, including 30-day mortality, arrhythmia, cerebrovascular disease and intracerebral haemorrhage, etc. Case-control and retrospective cohort studies were conducted to explore the risk factors associated with early postoperative complications, examine their relationship with postoperative management, explore independent risk factors of compound complications, and build predictive models.

Study Overview

• Status: Recruiting
• Conditions: Coronary Artery Bypass

• Study Type: Observational
• Enrollment (Estimated): 40000

Contacts and Locations

• Study Contact: Name: Ziping Li, MD; Phone Number: 88396666; Email: ziping_li@yeah.net
• Study Contact Backup: Name: Yiming Yan, MD; Phone Number: 88396666; Email: yanyiming325@163.com

Study Locations

• China
  • Beijing
    • Beijing, Beijing, China
      • Recruiting
      • Structral Heart Disease Center, Fuwai Hospital
      • Contact: Pan Xiangbin, MD, Ph.D; Phone Number: 010-88396666; Email: panxiangbin@fuwaihospital.org

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

Patients who accepted coronary artery bypass graft and met the eligibility criteria are enrolled for this study.

Description

Inclusion Criteria:

• patients accepted CABG enrolled from January 2013 to June 2023

Exclusion Criteria:

• patients discharged within 72 hours of admission
• patients with an admission diagnosis of atrial fibrillation
• patients underwent CABG as emergency surgery
• patients underwent concurrent surgical treatments
• patients with repeat admissions

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
30-day mortality	The proportion of patients who die within 30 days of being admitted to the hospital.	30 days

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
post-operative atrial fibrillation	The occurrence of atrial fibrillation after a patient has undergone surgery.	Around the second postoperative day.
MACE	A combination of several critical cardiovascular events may vary depending on the specific context of the study or clinical evaluation.	Around the second postoperative day.

Collaborators and Investigators

• Sponsor: Chinese Academy of Medical Sciences, Fuwai Hospital
• Investigators: Principal Investigator: Xiangbin Pan, MD, Fuwai Hospital, CAMS & PUMC

Study record dates

Study Major Dates

• Study Start (Actual): January 1, 2013
• Primary Completion (Estimated): June 30, 2026
• Study Completion (Estimated): June 30, 2026

Study Registration Dates

• First Submitted: June 28, 2024
• First Submitted That Met QC Criteria: June 28, 2024
• First Posted (Actual): July 5, 2024

Study Record Updates

• Last Update Posted (Actual): July 5, 2024
• Last Update Submitted That Met QC Criteria: June 28, 2024
• Last Verified: June 1, 2024

More Information

Terms related to this study

• Other Study ID Numbers: 2024-2276

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No