CAT Score and Airway Limitation in Adult Smokers (CAT)

Relationship Between CAT Score and Airway Limitation in Adult Smokers

This study aimed to show the relationship between CAT Score and airway limitation in smokers who applied to MSKU Chest Diseases Polyclinic with respiratory complaints (shortness of breath, cough, sputum, etc.) and underwent respiratory function tests. CAT Score is a measurement used to evaluate the quality of life of Chronic Obstructive Pulmonary Disease (COPD) patients. CAT Score is a scale used to assess patients' symptoms (such as shortness of breath, cough, and sputum) and problems affecting their daily activities. CAT Score usually takes a value between 0 and 40, and a high score may indicate that the patient's quality of life is low. There are studies on the usability of CAT Score in Bronchiectasis, Tuberculosis, and Asthma Diseases other than COPD. We hypothesize that there is a positive correlation between CAT Score and airway limitation in smokers before COPD develops. The study was planned as cross-sectional. Between July 2024 and December 2024, patients who apply to MSKU Chest Diseases Polyclinic with respiratory complaints and have a history of smoking will have their CAT scores, 6-minute walking test, and height and weight measurements performed and recorded. In our study, the comparison of CAT Scores of individuals who smoke and have normal respiratory function test parameters with those who are not normal but excluded from COPD is planned as the primary endpoint, and comparisons of CAT Scores with exercise capacities and body mass indexes are planned as the secondary endpoint.

Study Overview

• Status: Completed
• Conditions: Smokers

• Study Type: Observational
• Enrollment (Actual): 90

Contacts and Locations

Study Locations

• Turkey (Türkiye)
  • Muğla, Turkey (Türkiye), 48000
    • Muğla EAH

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

Patients who applied to MSKU Chest Diseases Polyclinic with respiratory complaints and had a history of smoking were subjected to respiratory function tests.

Description

Inclusion Criteria:

• Smoking history Being over 18 years old Being symptomatic

Exclusion Criteria:

• Having a diagnosis of chronic respiratory disease (COPD, Asthma, IPF)

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort
Smokers with airway limitation; Smokers with FEV1<80%
Smokers without airway limitation; smokers with FEV1>80

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
CAT	In our study, the primary endpoint was to compare the CAT scores of individuals who smoked and had normal pulmonary function test parameters with those who were not normal but excluded from COPD.	day 1

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
6MWT-BMI	Comparisons of exercise capacities and body mass indexes with CAT Scores are planned as secondary endpoints. Weight and height will be combined to report BMI in kg/m^2. 6mwt distance will be reported as meter	day 1

Collaborators and Investigators

• Sponsor: Muğla Sıtkı Koçman University

Study record dates

Study Major Dates

• Study Start (Actual): October 12, 2024
• Primary Completion (Actual): March 3, 2025
• Study Completion (Actual): March 10, 2025

Study Registration Dates

• First Submitted: October 11, 2024
• First Submitted That Met QC Criteria: October 14, 2024
• First Posted (Actual): October 16, 2024

Study Record Updates

• Last Update Posted (Actual): March 11, 2026
• Last Update Submitted That Met QC Criteria: March 10, 2026
• Last Verified: November 1, 2024

More Information

Terms related to this study

• Keywords: CAT; smoker
• Other Study ID Numbers: CAT24

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No