A Clinical Study of the Effects of Environmental Pollution on Obesity

October 31, 2024 updated by: Dong Peng
This study aims to assess the effects of environmental pollution (including environmental indicators such as PM2.5, PM5, PM10, SO2, NOX, O3, and greening index) on obese patients and to explore the possible mechanisms by which environmental pollution promotes obesity.

Study Overview

Status

Active, not recruiting

Conditions

Intervention / Treatment

Detailed Description

Firstly, the effects of environmental pollution on obese patients were investigated by analysing the baseline conditions and obesity levels (including BMI, waist circumference, hip circumference, etc.) and underlying diseases of obese patients in regions with different pollution levels. Secondly, the association between environmental pollution levels on blood test characteristics (including renal function, sex hormones, glucose tolerance test, trace elements, liver function and blood routine) of obese patients was investigated to find possible mechanisms.

Study Type

Observational

Enrollment (Estimated)

800

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • China
    • Chongqing
      • Chongqing, Chongqing, China, 400016
        • The First Affiliated Hospital of Chongqing Medical University
    • Yunnan
      • Kunming, Yunnan, China, 650000
        • Affiliated Hospital of Yunnan University
      • Kunming, Yunnan, China, 650000
        • The Second People's Hospital of Qujing

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

This is a retrospective observational study, which is expected to include patients diagnosed with obesity ( body mass index (BMI) ≥ 28 kg/m2).

Description

Inclusion Criteria:

  • Age ≥18 years;
  • obese patients with BMI ≥30;
  • patients without surgical treatment prior to enrolment;
  • willingness to participate in the study and sign an informed consent form;
  • complete clinical data.

Exclusion Criteria:

  • patients with systemic diseases such as severe cardiorespiratory insufficiency affecting the choice of treatment regimen;
  • patients assessed by the investigator to be inappropriate for enrolment;
  • patients with incomplete clinical data.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
the obesity group
Obese patients attending the First Affiliated Hospital of Chongqing Medical University, the Affiliated Hospital of Yunnan University, and the Second People's Hospital of Qujing City.
Diagnostic test: Obesity
diagnosis as obese patients

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
incidence of obesity
Time Frame: From 18 years old until the developing obesity, through study completion, an average of 5 year.
the time for overweight to obesity
From 18 years old until the developing obesity, through study completion, an average of 5 year.

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Dong Peng

Collaborators

Affiliated Hospital of Yunnan University
The Second People's Hospital of Qujing

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 1, 2011

Primary Completion (Estimated)

October 30, 2024

Study Completion (Estimated)

October 30, 2024

Study Registration Dates

First Submitted

October 31, 2024

First Submitted That Met QC Criteria

October 31, 2024

First Posted (Estimated)

November 1, 2024

Study Record Updates

Last Update Posted (Estimated)

November 1, 2024

Last Update Submitted That Met QC Criteria

October 31, 2024

Last Verified

October 1, 2024

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • ZZ2024-350-02

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

IPD Plan Description

Ethics committees of the clinical centres where the studies were conducted did not allow the release of patient data.

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Obesity and Overweight

Clinical Trials on Obesity

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Chile

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

Subscribe