Etiologies, Definitive Diagnosis and Patient Outcomes in Altered Level of Consciousness in the Emergency Department

When someone starts acting differently in terms of how alert or awake they are, it can be a tough situation for emergency (ER) department doctors.e exact and definitive etiologies of ALOC that can be intracranial or extracranial.

Study Overview

• Status: Active, not recruiting
• Conditions: Consciousness Disorders
• Intervention / Treatment: Diagnostic test: Consciousness in the Emergency Department

Detailed Description

The change in terms of mental state in accordance with how alert and awake patient is termed as altered level of consciousness. Etiologies will be classified by using convenience sampling. GCS<14 patients will be included in this study. Data will be collected through a slight modification in a pre-designed Performa. Reference point for the data collection will be the time of discharge from the emergency department. In Previous studies mostly, etiologies were classified as extracranial and intracranial. Some studies found neurological etiologies most dominant as an extra cranial and some studies found systematic infections ,metabolic causes and some demonstrated that intracranial etiologies were dominant. So, in this study we will find the definitive diagnosis in patient having ALOC which can be intracranial or extracranial. And also, it will be compared with GCS scale. This study will identify th

• Study Type: Observational
• Enrollment (Actual): 1

Contacts and Locations

Study Locations

• Pakistan
  • Punjab
    • Kashmir, Punjab, Pakistan
      • CMH RAWALAKOT AJK, District poonch , tehsil Rawalakot, AJK PAKISTAN

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Probability Sample

Study Population

Definitive Diagnosis and Patient Outcomes in Altered Level of Consciousness in the Emergency Department

Description

Inclusion Criteria:

• Patients with GCS<15, age group 18 years to 90 years which come in emergency department due to any etiology will be included in this study.

Exclusion Criteria:

• GCS = 15 will be excluded from the study.
• patients coming in any outpatient department setting or other than emergency department and age group <18 or > 90 will be excluded from this study.

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
GCS(GLASGOW COMMA SCALE)	The GCS is scored between 3 and 15, 3 being the worst and 15 the best. It is composed of three parameters: best eye response (E), best verbal response (V), and best motor response (M). The components of the GCS should be recorded individually.	12 Months

Collaborators and Investigators

• Sponsor: Superior University

Study record dates

Study Major Dates

• Study Start (Actual): February 28, 2024
• Primary Completion (Actual): June 30, 2024
• Study Completion (Estimated): March 1, 2025

Study Registration Dates

• First Submitted: December 17, 2024
• First Submitted That Met QC Criteria: December 19, 2024
• First Posted (Actual): March 25, 2025

Study Record Updates

• Last Update Posted (Actual): March 25, 2025
• Last Update Submitted That Met QC Criteria: December 19, 2024
• Last Verified: December 1, 2024

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Neurologic Manifestations; Nervous System Diseases; Mental Disorders; Neurobehavioral Manifestations; Neurocognitive Disorders; Consciousness Disorders
• Other Study ID Numbers: MSAHS/Batch-Spring23/017

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No