Investigation of the Effects of Proprioceptive Neuromuscular Facilitation Techniques and Core Stabilization Exercises on Physical and Functional Parameters in Adolescents With Idiopathic Scoliosis

June 17, 2025 updated by: Mehmet Hanifi Kaya, Kirsehir Ahi Evran Universitesi
Adolescent Idiopathic Scoliosis (AIS) is a prevalent three-dimensional torsional disorder, primarily affecting adolescents during puberty. Characterized by a lateral deviation of the spine greater than 10°, AIS can lead to physical and psychological issues, including back pain, cosmetic deformity, and reduced quality of life. This study aims to compare the effects of Proprioceptive Neuromuscular Facilitation (PNF) techniques and Core Stabilization exercises on physical and functional parameters in adolescents with idiopathic scoliosis. This randomized controlled trial was conducted with 52 adolescents aged 10-18 years, diagnosed with AIS (Cobb angle of 10-30°). Participants were randomly assigned to either the PNF group or the Core Stabilization group. Both groups underwent a 10-week supervised exercise program, supplemented by a home exercise regimen. Primary outcomes included changes in the Cobb angle and Angle of Trunk Rotation (ATR). Secondary outcomes assessed quality of life (SRS-22), perceived trunk appearance (WRVAS), and physical function (6MWT and STS).

Study Overview

Status

Completed

Intervention / Treatment

Detailed Description

Adolescent Idiopathic Scoliosis (AIS) is a prevalent three-dimensional torsional disorder, primarily affecting adolescents during puberty. Characterized by a lateral deviation of the spine greater than 10°, AIS can lead to physical and psychological issues, including back pain, cosmetic deformity, and reduced quality of life. This study aims to compare the effects of Proprioceptive Neuromuscular Facilitation (PNF) techniques and Core Stabilization exercises on physical and functional parameters in adolescents with idiopathic scoliosis. This randomized controlled trial was conducted with 52 adolescents aged 10-18 years, diagnosed with AIS (Cobb angle of 10-30°). Participants were randomly assigned to either the PNF group or the Core Stabilization group. Both groups underwent a 10-week supervised exercise program, supplemented by a home exercise regimen. Primary outcomes included changes in the Cobb angle and Angle of Trunk Rotation (ATR). Secondary outcomes assessed quality of life (SRS-22), perceived trunk appearance (WRVAS), and physical function (6MWT and STS).

Study Type

Interventional

Enrollment (Actual)

52

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

      • Kırşehir, Turkey, 40100
        • Mehmet Hanifi KAYA

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  1. Aged between 10 and 18 years old,
  2. First-time diagnosis of AIS,
  3. Risser sign of 0-3 and a Cobb angle of 10-30°,
  4. Sanders classification of 0-6,
  5. Lenke curve Type 1 or Type 1A,
  6. Volunteered to participate in the study.

Exclusion Criteria:

  1. The presence of other types of scoliosis (e.g., congenital or neuromuscular scoliosis),
  2. a history of spinal surgery,
  3. use of a brace,
  4. contraindications for exercise (e.g., cardiovascular or respiratory disorders),
  5. previous AIS treatment,
  6. rheumatological diseases, and/or other neuromuscular problems.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: PNF group
Proprioceptive Neuromuscular Facilitation Group: The Proprioceptive Neuromuscular Facilitation (PNF) PNF exercises focused on enhancing neuromuscular control, flexibility, and strength of the spinal and core muscles. The exercise regimen included spiral and diagonal movement patterns, rhythmic stabilization, and contract-relax techniques. Participants were instructed on the activation of the transverse abdominus (TrA) muscle, starting with palpation techniques to feel the muscle contraction. Exercises progressed from supine positions to more challenging postures, incorporating breathing control to avoid the Valsalva maneuver.
Exercise therapy was applied to individuals in both groups.
Active Comparator: core stabilization group
Core Stabilization Group: The core stabilization exercises aimed to improve the stability and strength of the core muscles, which are crucial for maintaining spinal alignment and posture. The exercise regimen included static and dynamic postural control exercises, balance training, and functional movement patterns. The core stabilization exercises focused on strengthening the deep trunk muscles, including the transverse abdominis, multifidus, and pelvic floor muscles.
Exercise therapy was applied to individuals in both groups.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Cobb
Time Frame: 24 weeks
The Cobb: Lines are drawn parallel to the upper edge of the superior vertebra and the lower edge of the inferior vertebra. Then, perpendicular lines are drawn to these parallel lines, and the angle between the two perpendiculars is measured. This angle, known as the Cobb angle, indicates the degree of scoliosis.
24 weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
The Walter Reed Visual Assessment Scale
Time Frame: 24 weeks
WRVAS: Perceived trunk appearance was evaluated using the Walter Reed Visual Assessment Scale (WRVAS), which assesses the cosmetic impact of scoliosis from the patient's perspective. The WRVAS consists of seven items, each scored from 1 (no deformity) to 5 (severe deformity), with a higher total score indicating a greater perceived deformity.
24 weeks
Trunk Rotation Angle,
Time Frame: 24 weeks
Trunk Rotation Angle: The ATR was evaluated using a scoliometer and Adam's forward bend test. Participants were asked to bend forward, and the ATR was measured at the apical vertebrae of the curve. This measurement is sensitive to changes in the rotational aspect of the scoliosis deformity.
24 weeks
Scoliosis Research Society-22
Time Frame: 24 weeks
Scoliosis Research Society-22: Quality of Life was assessed using the Scoliosis Research Society-22 (SRS-22) questionnaire, a validated self-report instrument that measures health-related QoL across five domains: function/activity, pain, self-image/appearance, mental health, and satisfaction with management. The total score is the average of the domain scores.
24 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 12, 2022

Primary Completion (Actual)

December 15, 2022

Study Completion (Actual)

February 10, 2023

Study Registration Dates

First Submitted

June 5, 2024

First Submitted That Met QC Criteria

December 27, 2024

First Posted (Actual)

January 6, 2025

Study Record Updates

Last Update Posted (Actual)

June 18, 2025

Last Update Submitted That Met QC Criteria

June 17, 2025

Last Verified

June 1, 2025

More Information

Terms related to this study

Other Study ID Numbers

  • 55485

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Adolescent Idiopathic Scoliosis

Clinical Trials on Exercise

Subscribe