Correlation Between Trunk Postural Changes by Mobile Application and Radiological Findings in Adolescent Idiopathic Scoliotic Females (TPSA-S)

This observational study aims to examine the relationship between trunk postural changes measured using a mobile application (Biotonix Posture Assistant) and spinal curvature assessed by radiographic Cobb angle in adolescent females with idiopathic scoliosis. Thirty girls aged 14 to 17 years with moderate scoliosis will undergo a single posture assessment using the mobile application and a standard spinal X-ray. The study seeks to determine whether mobile-based postural measurements can reliably reflect radiological findings, offering a non-invasive and radiation-free option for screening and monitoring spinal posture in adolescents with scoliosis.

Study Overview

• Status: Completed
• Conditions: Adolescent Idiopathic Scoliosis (AIS)

Detailed Description

Detailed Description

Adolescent idiopathic scoliosis is a common spinal deformity that typically develops during the adolescent growth period and predominantly affects females. Accurate assessment of spinal curvature is essential for clinical decision-making and follow-up; however, repeated radiographic evaluation exposes patients to ionizing radiation. Therefore, non-invasive assessment tools are increasingly needed.

This observational cross-sectional study aims to investigate the relationship between trunk postural deviations measured using the Biotonix Posture Assistant mobile application and radiographic Cobb angle measurements in adolescent females diagnosed with idiopathic scoliosis. Thirty female participants aged 14 to 17 years with moderate scoliosis (Cobb angle between 40° and 60°) will be recruited.

Each participant will undergo a single postural assessment using the mobile application to measure trunk rotation and translation along the X and Y axes while standing in a standardized position. Standard posteroanterior spinal radiographs will be used to determine Cobb angles as part of routine clinical evaluation. No therapeutic intervention will be applied as part of this study.

Statistical analysis will include correlation and regression methods to explore the association between postural parameters obtained from the mobile application and radiographic findings. The results of this study are expected to support the clinical utility of mobile-based posture assessment as a complementary, non-radiographic tool for screening and monitoring spinal deformities in adolescents

• Study Type: Observational
• Enrollment (Actual): 30

Contacts and Locations

Study Locations

• Egypt
  • Cairo, Egypt, 11728
    • Badr University in Cairo

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

Female adolescents aged 14-17 years

Diagnosed with adolescent idiopathic scoliosis

Description

Inclusion Criteria:

Female adolescents aged 14-17 years

Diagnosed with adolescent idiopathic scoliosis

Cobb angle between 40° and 60°

Ability to stand independently for posture assessment

Exclusion Criteria:

Congenital scoliosis

Neuromuscular scoliosis

Previous spinal surgery

Leg length discrepancy greater than 2 cm

Any musculoskeletal disorder affecting posture

Any neurological disorder affecting posture

Thyroid disease

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort

Adolescent Idiopathic Scoliosis Group; This group includes female adolescents aged 14 to 17 years diagnosed with moderate adolescent idiopathic scoliosis (Cobb angle 40°-60°). Participants undergo a single assessment of trunk posture using a mobile application (Biotonix Posture Assistant) and standard posteroanterior spinal radiography as part of routine clinical evaluation. No therapeutic or experimental intervention is applied in this study

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Correlation between BPA-derived trunk postural parameters and radiographic Cobb angle	baseline assessment at study enrollment

Secondary Outcome Measures

Outcome Measure	Time Frame
Correlation between trunk rotation (X and Y axes) and Cobb angle Correlation between trunk translation (X and Y axes) and Cobb angle Predictive value of BPA parameters for Cobb angle estimation	baseline assessment at study enrollment

Collaborators and Investigators

• Sponsor: Beni-Suef University

Study record dates

Study Major Dates

• Study Start (Actual): September 1, 2024
• Primary Completion (Actual): August 30, 2025
• Study Completion (Actual): August 30, 2025

Study Registration Dates

• First Submitted: January 30, 2026
• First Submitted That Met QC Criteria: February 6, 2026
• First Posted (Actual): February 13, 2026

Study Record Updates

• Last Update Posted (Actual): February 13, 2026
• Last Update Submitted That Met QC Criteria: February 6, 2026
• Last Verified: February 1, 2026

More Information

Terms related to this study

• Keywords: mobile application; Cobb angle; Adolescent idiopathic scoliosis; spinal assessment.; Biotonix
• Other Study ID Numbers: IRB0001P4233-41. (Other Identifier: ethical committee from Badr University in Cairo)

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No