Effects of Virtual Reality Hand Hygiene Simulation on Nurses' Hand Hygiene

August 13, 2026 updated by: Askin Selvi

Development and Evaluation of the Effectiveness of a Virtual Reality Simulation for Hand Hygiene Training: An In-Service Nursing Education Example

Healthcare-associated infections (HAIs) are an important patient safety concern, and hand hygiene is one of the most effective measures for preventing their transmission. However, hand hygiene compliance among healthcare professionals, including nurses, remains suboptimal. Innovative educational approaches may support the development of hand hygiene knowledge, behaviour, and compliance.

Virtual reality (VR) simulation provides an immersive and interactive learning environment that allows learners to practice clinical situations and reinforce knowledge and skills. In nursing education, VR simulation may facilitate the transfer of theoretical knowledge into practice and provide opportunities for repeated learning experiences.

This randomized controlled study evaluated the effectiveness of a VR-based hand hygiene simulation for nurses. Participants in both the experimental and control groups received standard hand hygiene training, while participants in the experimental group additionally received VR-based hand hygiene simulation. The study evaluated the effects of the intervention on nurses' hand hygiene knowledge, handwashing behaviour, and hand hygiene compliance.

Study Overview

Study Type

Interventional

Enrollment (Actual)

76

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

    • Avcılar
      • Istanbul, Avcılar, Turkey (Türkiye), 34320
        • Aşkin Selvi

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

Nurses who volunteered to participate in the study. Nurses who were actively working in the specified patient care units.

Exclusion Criteria:

Nurses who had received any hand hygiene training other than general orientation within the previous year.

Nurses with a history of epilepsy or seizures. Nurses with neurological or vision-related disorders that could interfere with the use of a VR headset.

Nurses with motion sickness that could interfere with the use of a VR headset.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Other
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: experimental group
Participants in the experimental group received standard hand hygiene training followed by the virtual reality (VR) hand hygiene simulation. The VR simulation provided an immersive and interactive learning experience in which participants practiced hand hygiene in simulated clinical scenarios.
Participants in the experimental group received standard hand hygiene training followed by a virtual reality (VR) hand hygiene simulation. The VR simulation provided an immersive and interactive learning environment in which nurses practiced hand hygiene in simulated clinical scenarios. The simulation was designed to reinforce hand hygiene knowledge and appropriate hand hygiene practices through an interactive learning experience.
Other: control group
Participants in the control group received standard hand hygiene training only and did not participate in the virtual reality hand hygiene simulation.
Participants received standard hand hygiene training covering the principles and recommended practices of hand hygiene. This training represented the standard educational intervention and did not include the virtual reality (VR) hand hygiene simulation.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Primary Outcome Measure - Title: Hand Hygiene Knowledge
Time Frame: Baseline, immediately after the intervention, and at 2-month follow-up
Hand hygiene knowledge was assessed using a 20-item Knowledge Test developed by the researchers based on the content of the hand hygiene training programme. The test was designed to assess nurses' level of knowledge regarding hand hygiene. Content validity was evaluated using the Lawshe technique based on the opinions of eight experts, and the content validity index was 0.99. Cronbach's alpha coefficient was 0.739 in the present study. Higher scores indicate a higher level of hand hygiene knowledge.
Baseline, immediately after the intervention, and at 2-month follow-up
Handwashing Behaviour
Time Frame: Baseline (pre-training), immediately after the intervention (post-training), and at 2-month follow-up
Handwashing behaviour was assessed using the Scale for Assessment of Hand Washing Behaviour in the Frame of Theory of Planned Behaviour. The scale consists of 46 items across eight subscales and assesses healthcare professionals' knowledge, beliefs, and attitudes regarding handwashing. Higher scores indicate stronger and more positive motivation toward handwashing. Cronbach's alpha coefficient was 0.943 in this study.
Baseline (pre-training), immediately after the intervention (post-training), and at 2-month follow-up
Hand Hygiene Compliance
Time Frame: Baseline (pre-training), within approximately 3 days after the intervention, and at 2-month follow-up
Hand hygiene compliance was assessed by direct observation using the Hand Hygiene Observation Form based on the WHO Five Moments for Hand Hygiene: before touching a patient, after touching a patient, after body fluid exposure risk, before clean/aseptic procedures, and after touching patient surroundings. Trained independent observers conducted the assessments, and each nurse was observed for 25 hand hygiene indications.
Baseline (pre-training), within approximately 3 days after the intervention, and at 2-month follow-up

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Investigators

  • Principal Investigator: AŞKIN SELVİ, Assistant Professor, İstanbul University-Cerrahpasa, Turkey

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

June 7, 2024

Primary Completion (Actual)

August 20, 2024

Study Completion (Actual)

September 1, 2024

Study Registration Dates

First Submitted

April 12, 2024

First Submitted That Met QC Criteria

January 22, 2025

First Posted (Actual)

January 23, 2025

Study Record Updates

Last Update Posted (Actual)

August 17, 2026

Last Update Submitted That Met QC Criteria

August 13, 2026

Last Verified

August 1, 2026

More Information

Terms related to this study

Other Study ID Numbers

  • İUC_ASELVİ_001
  • 124S279 (Other Identifier: The Scientific and Technological Research Council of Turkey)

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

IPD Plan Description

Study Protocol Statistical Analysis Plan Informed Consent Form Clinical Study Report Analytic Code

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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