Improving Quality of Life for Teenagers With Asthma (IMPAQT)

Can the Quality of Life of Adolescents With Asthma be Improved by Focusing on Improving Their Asthma Self-management

BACKGROUND: Asthma is a long-term lung condition affecting 1 in 11 children and young people in the UK. Many teenagers have well controlled asthma, but a significant number continue to experience regular symptoms and asthma attacks leading to hospitalisations. While non-adherence to medication is a factor, teenagers also face challenges like changing relationships with parents and peers, avoiding triggers like smoking, and fitting in treatment with daily life demands. Healthcare professionals (HCPs) also face difficulties in managing teenagers with asthma.

A previous study, funded by Asthma + Lung UK, developed a new approach to manage teenage asthma by focusing on self-efficacy, which is how confident one feels about performing a task. Teenagers completed the Adolescent Asthma Self-Efficacy Questionnaire (AASEQ), which identified areas where they needed more support. HCPs then tailored their consultations to address these needs. This approach improved the teenagers' confidence in self-managing their asthma.

Improving quality of life (QoL) is a key goal in asthma care. Therefore, the aim of this study is to determine if the self-efficacy approach improves QoL for teenagers with asthma.

METHODS: Teenagers aged 12-18 years with asthma will be recruited from hospital clinics. They will be randomly assigned to one of two groups:

1. Teenager will complete the AASEQ at the start of their appointment. The HCPs will use this to focus the consultation on areas where the teenager needs support in self-managing their asthma.
2. Teenager will have their usual consultation with the HCP.

Three months after the appointment, the QoL will be compared between the two groups using a standardised questionnaire.

IMPACT: If the self-efficacy approach proves to be beneficial, it could help HCPs to empower teenagers to better manage their asthma and ultimately improve their quality of life.

Study Overview

• Status: Recruiting
• Conditions: Asthma; Asthma in Children
• Intervention / Treatment: Other: Clinic consultation focused on asthma self-management

• Study Type: Interventional
• Enrollment (Estimated): 98
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Anna Rattu; Phone Number: +44 (0)23 8059 6835; Email: a.s.rattu@soton.ac.uk
• Study Contact Backup: Name: Graham Roberts; Phone Number: +44 (0)23 8059 8138; Email: g.c.roberts@soton.ac.uk

Study Locations

• United Kingdom
  • Hampshire
    • Southampton, Hampshire, United Kingdom, SO16 6Y
      • Recruiting
      • University Hospital Southampton NHS Foundation Trust
      • Contact: Graham Roberts; Phone Number: +44 (0)23 8059 8138; Email: g.c.roberts@soton.ac.uk
  • Isle of Wight
    • Isle of Wight, Isle of Wight, United Kingdom, PO30 5TG
      • Recruiting
      • Isle of Wight NHS Trust, St Mary's Hospital
      • Contact: Graham Roberts; Phone Number: +44 (0)23 8059 8138; Email: g.c.roberts@soton.ac.uk

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

• Adolescent aged 12-18 years
• Attending a paediatric respiratory clinic
• Informed consent from adolescent aged ≥16 years, and assent plus parent/guardian consent for adolescents aged ≤16 years
• Paediatric Asthma Quality of Life Questionnaire score ≤5.5 points

Exclusion Criteria:

• Aged 0-11 or over 18 years
• Other significant long-term medical condition that has a day-to-day impact on their lives (except for co-existing allergic conditions, breathing pattern disorder, dysfunctional breathing, or intermittent laryngeal obstruction)
• Adolescent or parent/guardian unable to communicate sufficiently to complete consent forms.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Supportive Care
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Clinic consultation focused on asthma self-management; The participant will complete the Adolescent Asthma Self-efficacy Questionnaire (AASEQ), and the clinic healthcare professional will use the responses to focus the consultation on areas where the participant needs support for asthma self-management.	Other: Clinic consultation focused on asthma self-management; The clinic healthcare professionals (HCPs) will be provided with the completed Adolescent Asthma Self-efficacy Questionnaire (AASEQ), which will help identify areas where participants need additional support to improve their asthma self-management skills. Targeted behavioural interventions, developed during the 'ItsMyAsthma' study, will be applied during the clinic consultation to address individual needs.
No Intervention: Usual clinic consultation; The participant will not complete the AASEQ at baseline and their healthcare professional will conduct the consultation as per usual management.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Paediatric Asthma Quality of Life Questionnaire (PAQLQ)	Paediatric Asthma Quality of Life Questionnaire score ranging from 0-36 points, with a higher score indicating worse quality of life.	3 months after enrolment

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Asthma-related healthcare utilisation	Asthma-related healthcare utilisation including number of asthma exacerbations requiring prednisolone/dexamethasone, and/or GP visits, Emergency Department, Hospital, or Intensive care admissions.	3 months after enrolment
Asthma Control Test (ACT)	Asthma Control Test score ranging from 5-25 points, with a higher score indicating better asthma control.	3 months after enrolment
Adolescent Asthma Self-Efficacy Questionnaire (AASEQ)	Adolescent Asthma Self Efficacy Questionnaire score ranging from 0-100 points, with a higher score indicating greater self-efficacy for management of asthma.	3 months after enrolment

Collaborators and Investigators

• Sponsor: University Hospital Southampton NHS Foundation Trust
• Investigators: Study Director: Anna Rattu, University of Southampton

Study record dates

Study Major Dates

• Study Start (Actual): August 26, 2025
• Primary Completion (Estimated): August 1, 2027
• Study Completion (Estimated): November 1, 2027

Study Registration Dates

• First Submitted: February 24, 2025
• First Submitted That Met QC Criteria: February 27, 2025
• First Posted (Actual): February 28, 2025

Study Record Updates

• Last Update Posted (Actual): January 5, 2026
• Last Update Submitted That Met QC Criteria: December 30, 2025
• Last Verified: December 1, 2025

More Information

Terms related to this study

• Keywords: Adolescent; Asthma; Quality of life; Self-efficacy; Asthma control
• Additional Relevant MeSH Terms: Immune System Diseases; Respiratory Tract Diseases; Lung Diseases; Bronchial Diseases; Lung Diseases, Obstructive; Respiratory Hypersensitivity; Hypersensitivity, Immediate; Hypersensitivity; Asthma
• Other Study ID Numbers: RHM CHI1258; 349662 (Other Identifier: Integrated Research Approval System (IRAS))

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: YES
• IPD Plan Description: Please contact the study investigators to request trial data. Note that it will need to be anonymised before sharing.

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No