Augmentation of Facial Wall in Defective Fresh Extraction Site for Immediate Implant Placement

September 3, 2025 updated by: Nuhayra Ashour Muhammed
The study is performed to clinically and radiographically assess the efficacy of using enriched bone graft combined with slowly resorbable membrane on bone quality in immediate implant placement in extraction socket in cases with localized facial bone defect.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

The study is include twelve participants , and the patients are in rolled in two groups, group one receive implant, sticky bone and laminar bone membrane . group two receive implant, sticky bone and pericardium membrane using vestibular incision and 6 months post operative radiographically assessment is performed to measure labial bone quantity formed .

Study Type

Interventional

Enrollment (Actual)

12

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
      • Cairo, Egypt
        • Faculty of Dental Medicine for Girls

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • patient with a single hopeless tooth in maxillary anterior region.
  • sufficient bone apically and palatally
  • presence of natural contralateral tooth for the tooth being replaced
  • systemic healthy patients

Exclusion Criteria:

  • extraction socket type III
  • acute infection in hopeless tooth
  • a heavy smoker patient
  • pregnant
  • had received chemotherapy or radiotherapy in previous year

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: laminar bone membrane
hopeless tooth extraction then immediate implant placed , then by using vestibular incision placing laminar bone membrane under the mucogingival tunnel and fill the gap between the laminar bone membrane and the implant with sticky bone
Procedure: laminar bone membrane for labial bone augmentation
adding laminar bone membrane in one group and pericardium membrane in another group with sticky bone by using vestibular incision in both groups to augment the labial bone over dental implant
Other Names:
  • pericardium membrane for labial bone augmentation
Experimental: pericardium membrane
hopeless tooth extraction then immediate implant placed , then by using vestibular incision placing pericardium membrane under the mucogingival tunnel and fill the gap between the pericardium membrane and the implant with sticky bone
Procedure: laminar bone membrane for labial bone augmentation
adding laminar bone membrane in one group and pericardium membrane in another group with sticky bone by using vestibular incision in both groups to augment the labial bone over dental implant
Other Names:
  • pericardium membrane for labial bone augmentation

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
primary stability of implant in Newton centimeter and soft tissue healing
Time Frame: one week postoperative
Dental implant ratchet to show implant stability and Pink esthetic score for soft tissue healing measurement
one week postoperative

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
labial bone thickness formation in millimeters
Time Frame: 6 months postoperative
Cone beam computed tomography to show labial bone thickness
6 months postoperative

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Nuhayra Ashour Muhammed

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

September 15, 2022

Primary Completion (Actual)

August 6, 2024

Study Completion (Actual)

April 1, 2025

Study Registration Dates

First Submitted

January 5, 2025

First Submitted That Met QC Criteria

March 5, 2025

First Posted (Actual)

March 10, 2025

Study Record Updates

Last Update Posted (Estimated)

September 4, 2025

Last Update Submitted That Met QC Criteria

September 3, 2025

Last Verified

March 1, 2025

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • OR SUR-102-1-E

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

Yes

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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