Human TECAR on Exercise Preconditioning and Post-exercise Recovery

May 6, 2025 updated by: Ernesto Cesar Pinto Leal Junior, University of Nove de Julho
TECAR therapy (Transfer of Energy Capacitive and Resistive) is a type of diathermy that uses radiant energy to generate endogenous heat. However, to the date there are no studies investigating the effects of TECAR therapy on exercise preconditioning and post-exercise recovery in humans. Therefore, the aim of this project is to assess the effects of different treatment protocols of TECAR therapy on. exercise preconditioning and post-exercise recovery in humans

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Detailed Description

Fifty male healthy volunteers will be enrolled in a randomized, double-blind (participants and assessors), controlled trial. Volunteers will be allocated in 5 groups of 10 participants each: 1 - Sham-control (fake intervention - massaging with one of the Human TECAR probes with the device turned off before or after the eccentric exercise protocol depending on randomization); 2 - Capacitive mode before exercise (preconditioning); 3 - Resistive mode before exercise (preconditioning); 4 - Capacitive mode after exercise (recovery); and 5 - Resistive mode after exercise (recovery). The treatment target will be the knee extensors muscles (quadriceps).

A standardized knee extension eccentric exercise protocol performed in the isokinetic dynamometer (Biodex System 4) will be used in order to exercise induce skeletal muscle fatigue and damage.

Volunteers will be treated with Human TECAR in a single treatment session, with 10 minutes length, that will be carried out immediately before or immediately after the exercise protocol according to the randomization.

Study Type

Interventional

Enrollment (Estimated)

50

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Brazil
    • SP
      • São Paulo, SP, Brazil, 01504-001
        • Recruiting
        • Laboratory of Phototherapy and Innovative Technologies in Health
        • Contact:
        • Principal Investigator:
          • Pinto Leal Junior, Ph.D., M.Sc., PT.

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Physically active male participants;
  • Do not present a history of musculoskeletal injury in the regions of the hips, knees and calves in the month preceding the study;
  • Are not using pharmacological agents;
  • Voluntarily commit to participate in all stages of the study.

Exclusion Criteria:

  • Present musculoskeletal or joint injuries during data collection;
  • Present history of musculoskeletal injury in the regions of the hips, knees and calves in the month preceding the study.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Triple

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Sham Comparator: Sham-control
Fake intervention - massaging the quadriceps with one of the Human TECAR probes with the device turned off for 10 minutes, before or after the eccentric exercise protocol depending on randomization
Device: Sham Comparator
Massaging the quadriceps with one of the Human TECAR probes with the device turned off for 10 minutes
Experimental: Capacitive mode before exercise
Capacitive mode applied to the quadriceps for 10 minutes, before the eccentric exercise (preconditioning)
Device: Capacitive mode before
Capacitive mode applied to the quadriceps for 10 minutes
Experimental: Resistive mode before exercise
Resistive mode applied to the quadriceps for 10 minutes, before the eccentric exercise (preconditioning)
Device: Resistive mode before
Resistive mode applied to the quadriceps for 10 minutes
Experimental: Capacitive mode after exercise (recovery)
Capacitive mode applied to the quadriceps for 10 minutes, after the eccentric exercise (recovery)
Device: Capacitive mode after
Capacitive mode applied to the quadriceps for 10 minutes
Experimental: Resistive mode after exercise (recovery)
Resistive mode applied to the quadriceps for 10 minutes, after the eccentric exercise (recovery)
Device: Resistive mode after
Resistive mode applied to the quadriceps for 10 minutes

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Change in muscle strength
Time Frame: 48 hours after eccentric exercise
The muscle strength will be measured through isokinetic dynamometry
48 hours after eccentric exercise

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Change in muscle strength
Time Frame: 5 minutes after the treatment, 5 minutes, 1 hour, 24 hours, 72 hours, and 96 hours after the eccentric exercise protocol
The muscle strength will be measured through isokinetic dynamometry
5 minutes after the treatment, 5 minutes, 1 hour, 24 hours, 72 hours, and 96 hours after the eccentric exercise protocol
Change in CK activity
Time Frame: 5 minutes after the treatment, 5 minutes, 1 hour, 24 hours, 72 hours, and 96 hours after the eccentric exercise protocol
The CK activity will be analyzed from the blood samples collected from the participants through biochemical analysis and using specific reagent kits.
5 minutes after the treatment, 5 minutes, 1 hour, 24 hours, 72 hours, and 96 hours after the eccentric exercise protocol
Delayed onset muscle soreness - DOMS
Time Frame: 5 minutes after the treatment, 5 minutes, 1 hour, 24 hours, 72 hours, and 96 hours after the eccentric exercise protocol
DOMS will be assessed through the VAS scale
5 minutes after the treatment, 5 minutes, 1 hour, 24 hours, 72 hours, and 96 hours after the eccentric exercise protocol
Temperature
Time Frame: 5 minutes after the treatment, 5 minutes, 1 hour, 24 hours, 72 hours, and 96 hours after the eccentric exercise protocol
Thigh temperature will be assessed through Thermography using the WellVu camera.
5 minutes after the treatment, 5 minutes, 1 hour, 24 hours, 72 hours, and 96 hours after the eccentric exercise protocol
Muscular oxygen saturation index
Time Frame: 5 minutes after the treatment, 5 minutes, 1 hour, 24 hours, 72 hours, and 96 hours after the eccentric exercise protocol
It will be measured using near-infrared spectroscopy (NIRS)
5 minutes after the treatment, 5 minutes, 1 hour, 24 hours, 72 hours, and 96 hours after the eccentric exercise protocol
Muscular blood flow
Time Frame: 5 minutes after the treatment, 5 minutes, 1 hour, 24 hours, 72 hours, and 96 hours after the eccentric exercise protocol
It will be measured analyzing total hemoglobin in muscle tissue using near-infrared spectroscopy (NIRS)
5 minutes after the treatment, 5 minutes, 1 hour, 24 hours, 72 hours, and 96 hours after the eccentric exercise protocol
Muscular effort perception
Time Frame: 5 minutes after the treatment, 5 minutes, 1 hour, 24 hours, 72 hours, and 96 hours after the eccentric exercise protocol
The CR-100 Effort Perception Scale will be used
5 minutes after the treatment, 5 minutes, 1 hour, 24 hours, 72 hours, and 96 hours after the eccentric exercise protocol
Participant satisfaction with the treatment
Time Frame: 96 hours after the eccentric exercise protocol
The Likert scale will be used
96 hours after the eccentric exercise protocol

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Nove de Julho

Investigators

  • Principal Investigator: Ernesto Cesar Pinto Leal Junior, Ph.D., M.Sc., PT., Nove de Julho University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

April 23, 2025

Primary Completion (Estimated)

May 30, 2025

Study Completion (Estimated)

May 30, 2025

Study Registration Dates

First Submitted

March 31, 2025

First Submitted That Met QC Criteria

April 14, 2025

First Posted (Actual)

April 22, 2025

Study Record Updates

Last Update Posted (Actual)

May 11, 2025

Last Update Submitted That Met QC Criteria

May 6, 2025

Last Verified

May 1, 2025

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • 7.083.912

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Plan Description

Data will be shared upon request addressed to the principal investigator.

IPD Sharing Time Frame

The data will become available six months after the manuscript publication for five years after that.

IPD Sharing Access Criteria

All IPD that underlie results in a publication will be available on reasonable request.

IPD Sharing Supporting Information Type

  • STUDY_PROTOCOL
  • SAP
  • CSR

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

Yes

product manufactured in and exported from the U.S.

Yes

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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