The Correlation of Clinical and Ultrasonographic Findings in Dorsoradial Wrist Pain Patients: Cross Sectional Study

May 12, 2025 updated by: ilkyazyagar, Fatih Sultan Mehmet Training and Research Hospital
This study aims to investigate the correlation between ultrasonographic and clinical findings in dorsoradial wrist pain. There are several etiologies for dorsoradial wrist pain, including carpometacarpal joint arthritis, De Quervain's tenosynovitis, proximal and distal intersection syndrome, Wartenberg syndrome, and ganglion cysts. In these clinical scenarios, certain physical examination tests are utilized, such as the Finkelstein test for De Quervain's tenosynovitis; however, this test may also yield positive results in cases of severe joint arthritis. Ultrasonography is proposed as a complementary tool for differential diagnosis. The investigators aim to examine the correlation between clinical test results and ultrasonographic parameters such as tendon thickness in the first extensor compartment, carpometacarpal joint synovitis, cortical irregularities, and the presence of osteophytes. Functional status will be assessed using the QuickDASH and FIHOA questionnaires.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

In the assessment of the first carpometacarpal (CMC) joint, the following ultrasonographic parameters will be evaluated: synovitis, presence of osteophytes, joint surface irregularity, and Doppler signal activity. Additionally, conventional hand radiographs of all participants will be reviewed to support the imaging findings.

For the evaluation of De Quervain's tenosynovitis, tendon sheath thickness, tendon cross-sectional area, and intratendinous Doppler activity will be measured. At the anatomical intersection zones of the first dorsal compartment, the presence of peritendinous fluid and associated Doppler activity will also be assessed to identify potential sites of friction or inflammation.

Assessment of the superficial radial nerve will include measurement of its cross-sectional area. A cross-sectional area exceeding one square millimeter will be considered indicative of possible neuropathy.

Study Type

Observational

Enrollment (Actual)

45

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey
    • Ataşehir
      • Istanbul, Ataşehir, Turkey, 34752
        • University of Health Sciences, FSM Training and Research Hospital, Istanbul

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Probability Sample

Study Population

patients who referred physical theraphy and rehabilitation and orthopedia clinics with dorsoradial wrist and thumb pain

Description

Inclusion Criteria:

  • pain in dorsoradial wrist

Exclusion Criteria:

  • known rheumatological disease
  • history of forearm, wrist, hand fracture
  • history of forearm, wrist, hand operation
  • mental retardation
  • history of major trauma in forearm, wrist and hand
  • fibromyalgia

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Odds Ratio of First Extensor Compartment Tendon Sheath Thickness Associated with De Quervain Disease
Time Frame: At the time of enrollment
To quantify the association between increased tendon sheath thickness and clinical diagnosis of De Quervain tenosynovitis using logistic regression analysis.
At the time of enrollment
Odds Ratio of Synovial Hypertrophy in CMC Joint Associated with Carpometacarpal Arthritis
Time Frame: At the time of enrollment
To assess the strength of association between ultrasonographic synovial hypertrophy and clinical diagnosis of carpometacarpal joint arthritis.
At the time of enrollment
Sensitivity of Ultrasonographic Parameters for Diagnosing Dorsoradial Wrist Pathologies
Time Frame: At the time of enrollment
To assess the diagnostic sensitivity of individual ultrasonographic findings (e.g., tendon sheath thickness, synovial hypertrophy) for detecting De Quervain tenosynovitis and CMC arthritis.
At the time of enrollment
Specificity of Ultrasonographic Parameters for Diagnosing Dorsoradial Wrist Pathologies
Time Frame: At the time of enrollment
To assess the diagnostic specificity of individual ultrasonographic findings for identifying De Quervain tenosynovitis and CMC arthritis.
At the time of enrollment

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Fatih Sultan Mehmet Training and Research Hospital

Investigators

  • Principal Investigator: Ilkyaz Yağar, Resident, University of Health Sciences, FSM Training and Research Hospital, Istanbul
  • Study Director: Esra Giray, Associated Professor, University of Health Sciences, FSM Training and Research Hospital, Istanbul
  • Study Chair: Aslınur Keleş, University of Health Sciences, FSM Training and Research Hospital, Istanbul
  • Study Chair: Feyza Unlu Ozkan, Professor, University of Health Sciences, FSM Training and Research Hospital, Istanbul
  • Study Chair: Ilknur Aktas, Professor, University of Health Sciences, FSM Training and Research Hospital, Istanbul
  • Study Chair: Ozge Gulsum Illeez, Associated Professor, University of Health Sciences, FSM Training and Research Hospital, Istanbul

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

July 29, 2024

Primary Completion (Actual)

October 6, 2024

Study Completion (Actual)

October 6, 2024

Study Registration Dates

First Submitted

March 23, 2025

First Submitted That Met QC Criteria

May 12, 2025

First Posted (Estimated)

May 20, 2025

Study Record Updates

Last Update Posted (Estimated)

May 20, 2025

Last Update Submitted That Met QC Criteria

May 12, 2025

Last Verified

June 1, 2024

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • E-10840098-202.3.02-3745

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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