Effect of Russian Current on Hand Grip Strength and Functional Outcome After Carpal Tunnel Release (CTS)

this study will be conducted to investigate the effect of Russian current on hand grip strength and functional outcome after carpal tunnel release

Study Overview

• Status: Completed
• Conditions: Carpal Tunnel Syndrome
• Intervention / Treatment: Other: russian current; Other: selected physical therapy program

Detailed Description

Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy syndrome of the upper extremities , the estimated prevalence is 4-5% in the general population ,it occurs due to median nerve compression in carpal tunnel and it is ten times more common in women ,the most common symptoms are numbness and tingling in the radial 3-1/2 finger, night pain, and paresthesias. Although it is most commonly idiopathic, other causes include trauma, oral contraceptive use, pregnancy, arthritis, diabetes hypothyroidism, and repetitive wrist movements. It is well known that distal radius fractures and their sequelae can cause CTS, this suggests that anatomic changes in bony structures of wrist may also contribute to the development of CTS.Russian current (RC), a well-known neuromuscular electrical stimulation operating at 2500 Hz, has demonstrated significant strength improvement over traditional exercises due to its high tolerance and low pain provocation.There are studies about efficacy of Transcutaneous electrical nerve stimulation on wrist pain in patients with CTR but there is lack of literature about efficacy of RC on hand grip strength and function after CTR so this stidu will be conducted.

• Study Type: Interventional
• Enrollment (Actual): 52
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Egypt
  • Giza Governorate
    • Cairo, Giza Governorate, Egypt, 11829
      • Nawal Sayed

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

• Fifty-two patients with hand muscles weakness post operative carpal tunnel release ,due to severe carpal tunnel syndrome .
• Patient's age will range from 30 to 50 years.
• Patient's body mass index (BMI) will be less than 30kg/m2.
• Presence of wrist pain associated with hand grip weakness.

Exclusion Criteria:

• Patients with any other musculoskeletal or neurological disorders in the hand.
• Patients with a history of fractures and dislocations in the hand and wrist.
• Patients with hand deformities and edematous hands.
• Patients with cervical radiculopathy.
• Carpal tunnel syndrome due to conditions like hypothyroidism, rheumatoid arthritis, immunosuppression

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: russian current; 26 patients will receive Russian current plus a selected physical therapy program three times a week for four weeks.	Other: russian current; russian current will be applied in 50Hz sinusoidal bursts with a duty cycle of 50% (10 s on/10 s off). Russian Stimulation (at 2500Hz or 2.5kHz) has been shown to be effective in increasing muscle strength and torque generation through stimulation of type II muscle fiber. The stimulation will be given for duration of 20 minutes , three tims per week plus selected physical therapy program.; Other: selected physical therapy program; Patients will receive selected physical therapy program
Active Comparator: Selected physical therapy program; 26 patients will receive selected physical therapy program three times a week for four weeks.	Other: selected physical therapy program; Patients will receive selected physical therapy program

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
hand grip strength	hand grip strength will be measured by hand held dynamometer.	up to four weeks
hand function	hand function will be measured by boston carpal tunnel questionnaire.The Boston Carpal Tunnel Questionnaire (BCTQ) is a patient-reported questionnaire used to assess symptoms and functional limitations in people with carpal tunnel syndrome (CTS). It consists of two modules: an 11-item Symptom Severity Scale (SSS) and an 8-item Functional Status Scale (FSS), which are scored independently on a 1-to-5 Likert scale.A mean score between 1 and 5 is generated for both the SSS and FSS, with higher scores indicating more severe symptoms or greater functional limitation.	up to four weeks

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
wrist range of motion	goniometer device will be used to assess wrist range of motion	up to four weeks
pain intensity	pain will be measured by visual analogue scale. Scores are based on self-reported measures of symptoms that are recorded with a single handwritten mark placed at one point along the length of a 10-cm line that represents a continuum between the two ends of the scale-"no pain" on the left end (0 cm) of the scale and the "worst pain" on the right end of the scale (10 cm).	up to four weeks

Collaborators and Investigators

• Sponsor: Cairo University

Study record dates

Study Major Dates

• Study Start (Actual): September 15, 2025
• Primary Completion (Actual): February 16, 2026
• Study Completion (Actual): February 16, 2026

Study Registration Dates

• First Submitted: September 3, 2025
• First Submitted That Met QC Criteria: September 3, 2025
• First Posted (Actual): September 10, 2025

Study Record Updates

• Last Update Posted (Actual): May 20, 2026
• Last Update Submitted That Met QC Criteria: May 18, 2026
• Last Verified: May 1, 2026

More Information

Terms related to this study

• Keywords: carpal tunnel syndrome; hand grip strength; russian current
• Additional Relevant MeSH Terms: Nervous System Diseases; Wounds and Injuries; Neuromuscular Diseases; Peripheral Nervous System Diseases; Median Neuropathy; Mononeuropathies; Nerve Compression Syndromes; Cumulative Trauma Disorders; Sprains and Strains; Carpal Tunnel Syndrome
• Other Study ID Numbers: P.T.REC/012/005964

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No