Progressive Relaxation and Psychoeducation in Patients With Hematological Malignancies

The Effect of Progressive Relaxation and Psychoeducation on Perceived Stress and Hope in Patients With Hematologic Malignancies: A Non-Randomized Study

This study will be conducted to determine the effect of progressive relaxation and psychoeducation on perceived stress and hope in patients with hematological malignancies

Study Overview

• Status: Active, not recruiting
• Conditions: Hematological Cancer
• Intervention / Treatment: Behavioral: Muscle Relaxation; Behavioral: psychoeducation or Atomoxetine or stimulants according to ADHD severity

Detailed Description

Being healthy requires being in a state of complete physical and mental well-being. Therefore, mental and physical well-being must be maintained together. While each individual already has different stressors, the fact that hematological malignancies are chronic and immune-mediated diseases increases the stress factors perceived by individuals, and the difficulty and uncertainty of the process reduces their level of hope. This triggers the use of ineffective coping methods. Patients with high perceived stress levels and declining hope levels are unable to adequately manage the disease process. Consequently, mortality and morbidity rates increase. This experimentally planned study will be conducted between February 2026 and November 2026 at the Adult Inpatient Hematology Clinic of Gazi University Faculty of Medicine Hospital. The study will involve 75 individuals hospitalized at the clinic who meet the inclusion criteria. It is a non-randomized study with 2 intervention groups and 1 control group. Intervention group A (progressive relaxation group, n=25), intervention group B (psychoeducation, n=25), and control group (routine care, n=25). Patients in intervention group A will undergo a 3-week, 6-session progressive relaxation exercise program, conducted individually and face-to-face. Intervention Group B will receive a 3-week, 6-session, individual, face-to-face psychoeducation program. The control group will receive 3 weeks of routine nursing care identical to that provided to the other groups. In this study, which will include pre- and post-tests, data will be collected face-to-face using the perceived stress level scale and the Herth hope index scale. The primary objective of this study is to examine the effects of progressive relaxation and psychoeducation interventions on perceived stress and hope levels in patients with hematological malignancies.

• Study Type: Interventional
• Enrollment (Estimated): 75
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Turkey (Türkiye)
  • Seydi̇şehi̇r
    • Konya, Seydi̇şehi̇r, Turkey (Türkiye), 42000
      • Seydişehir Kamil Akkanat Sağlik Bilimleri Fakültesi

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

1. 18 years of age or older
2. Diagnosis of hematologic malignancy
3. Ability to read and write
4. Volunteer to participate in the study

Exclusion Criteria:

1. Dementia and/or organic mental disorder
2. Sensory loss related to vision and hearing
3. Communication barrier
4. Physical disability
5. Respiratory distress
6. Bone marrow transplant procedure

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Supportive Care
• Allocation: Non-Randomized
• Interventional Model: Sequential Assignment
• Masking: None (Open Label)

Number of Arms

3

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Active Comparator: Progressive relaxation; Progressive relaxation; n=25: After the pre-test, 6 sessions (2 sessions per week) were planned for 3 weeks for individuals in this group. Each session will be conducted individually with patients, face-to-face, and will last 40-45 minutes. The post-test was administered after 3 weeks. PROGRESSIVE RELAXATION SESSION TITLES: SESSION: Introduction, Establishing Trust and the Concept of Relaxation; SESSION: Coping with a Cancer Diagnosis & Introduction to the Progressive Relaxation Technique; SESSION: Progressive Muscle Relaxation Application - Upper Body3; SESSION: Progressive Muscle Relaxation - Lower Body; SESSION: Whole Body Relaxation - Reinforcing the Application; SESSION: Integrating Progressive Relaxation into Daily Life & Closing	Behavioral: Muscle Relaxation; Progressive relaxation is a relaxation technique based on tensing and relaxing muscles in sequence. The goal is to achieve physical and mental relaxation by feeling the difference between tension and relaxation. It is frequently used for stress, anxiety, sleep problems, and psychosomatic disorders. When practiced regularly, it increases a person's ability to relax and contributes to their overall well-being.; Teaching progressive relaxation exercises to individuals diagnosed with cancer and supporting psychological well-being by reducing stress levels and increasing hope levels through these exercises (emotional gain); Reducing muscle tension and providing physical relaxation (psychomotor gain); To reduce stress and anxiety (emotional gain); To increase body awareness (emotional gain); To teach mental and physical relaxation (psychomotor gain); To provide emotional relief (emotional gain); To develop self-relaxation skills (psychomotor gain)
Active Comparator: psychoeducation; psychoeducation; n=25: After the pre-test, 6 sessions (2 sessions per week) were planned for 3 weeks for the individuals in this group. Each session will be conducted individually with patients, face-to-face, and will last 40-45 minutes. A post-test was administered after 3 weeks. Four expert opinions were obtained regarding the content. PSYCHOEDUCATION SESSION TITLES: 1. SESSION: INTRODUCTION AND PROGRAM OVERVIEW 2nd SESSION: UNDERSTANDING THE DISEASE - EMPOWERING THROUGH KNOWLEDGE 3rd SESSION: IDENTIFYING PERCEIVED STRESS AND ITS EFFECTS 4. SESSION: COPING WITH STRESS AND INTRODUCTION TO HOPE 5. SESSION: UNDERSTANDING AND STRENGTHENING HOPE 6. SESSION: INTERNALIZING WHAT HAS BEEN LEARNED, MAINTAINING AND EVALUATING	Behavioral: psychoeducation or Atomoxetine or stimulants according to ADHD severity; Psychoeducation is a structured educational process that provides individuals with information about mental illnesses, ways to cope with stress, and healthy living skills. The goal is to help the person understand their illness and symptoms, learn coping methods, and increase their compliance with treatment. It has both an informative and a supportive aspect. INTERVENTION B (PSYCHOEDUCATION) GROUP APPLICATION: A total of 6 sessions will be held with patients in intervention group B, twice a week for 3 weeks.; Each session will last an average of 45 minutes.; The 'Perceived Stress Level' scale and the 'Herth Hope Index' scale will be administered after the first session.; The 'Perceived Stress Level' scale and the 'Herth Hope Index' scale will be administered after the final session.
No Intervention: routine nursing care; routine nursig care; n=25 No intervention was performed after the pre-test; routine nursing care was administered. The post-test was administered after 3 weeks.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Herth hope index level scale	Herth Hope Index: Developed by Kaye Herth (1992), its validity and reliability in Turkish were studied by Aslan and colleagues (2007). The scale consists of a total of 12 items: "Future" (questions 1, 2, 6, 11), "Positive readiness and expectation" (questions 4, 7, 10, 12), and "Connections with oneself and others" (questions 3, 5, 8, 9).	9 months
perceived stress level scales	PERCEIVED STRESS SCALE: The adaptation of the perceived stress scale developed by Cohen, Kamarck, and Mermelsten (1983) into Turkish was carried out by Eskin et al. (2013). The perceived stress scale, consisting of a total of 14 items, aims to measure how stressful individuals perceive their life situations to be..	9 months

Collaborators and Investigators

• Sponsor: Necmettin Erbakan University

Study record dates

Study Major Dates

• Study Start (Actual): February 1, 2026
• Primary Completion (Estimated): November 30, 2026
• Study Completion (Estimated): November 30, 2026

Study Registration Dates

• First Submitted: September 11, 2025
• First Submitted That Met QC Criteria: November 18, 2025
• First Posted (Actual): November 26, 2025

Study Record Updates

• Last Update Posted (Actual): May 15, 2026
• Last Update Submitted That Met QC Criteria: May 14, 2026
• Last Verified: May 1, 2026

More Information

Terms related to this study

• Keywords: stress; hematologic malignancy; hope; psychoeducation; progressive relaxation
• Additional Relevant MeSH Terms: Neoplasms by Site; Neoplasms; Hematologic Diseases; Hemic and Lymphatic Diseases; Hematologic Neoplasms; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena; Organic Chemicals; Amines; Propylamines; Muscle Contraction; Atomoxetine Hydrochloride; Muscle Relaxation
• Other Study ID Numbers: NEÜ-SBF-TKA-02

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No