Effect of Video Laryngoscopy Versus Conventional Laryngoscopy Upon Hemodynamics

May 27, 2026 updated by: Muhammad Haroon Anwar, Pakistan Institute of Medical Sciences

Comparison Of Hemodynamic Stress Response To Laryngoscopy With Video Laryngoscopy Versus Macintosh Laryngoscopy In Patients Undergoing Elective Surgeries Under General Anesthesia

In general anestheisa airway is secured by passing a tube down the widpipe. This helps the patient to breath via ventilator during anesthesia. For placing this tube laryngoscopy is done which results in increase in blood pressure and heart rate. This study will compare the rise in blood pressure and heart rate among when using video laryngoscope with conventional laryngoscope.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

In this study Patients will be randomly divided into two groups with group V patients being intubated using Videolaryngoscope while group M patients will be intubated using Macintosh laryngoscope. The amount of rise in blood pressure and heart rate as a result of laryngoscopy will be noted.

Study Type

Interventional

Enrollment (Actual)

208

Phase

  • Phase 4

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Pakistan
      • Islamabad, Pakistan, 44000
        • Deparment of Anesthesia PIMS

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Elective surgeries under General Endotracheal Anesthesia. ASA class I and II.

Exclusion Criteria:

  • Pregnancy

    • Body mass index >35 kg/m2
    • No teeth
    • Maxillofacial trauma
    • Limited Cervical spine movement
    • Upper Airway Tumors
    • Preoperative assessment indicating difficult airway requiring use of video laryngoscope or fiberoptic intubation.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Prevention
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Video laryngoscopy
Patient in this group will be intubated using hyperangulated C MAC video laryngoscope
Device: C MAC hyperangulated video laryngoscopy
Patient will be intubated using hyperangulated C MAC video laryngoscope
Active Comparator: Conventional Laryngoscopy
Patient in this group will be intubated using conventional macintosh laryngoscopic blade
Device: Conventional macintosh laryngoscopy
Patient in this group will be intubated using conventional macintosh laryngoscopy

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Heart Rate
Time Frame: Upon arrival in OR (baseline) then immediately following intubation (T1) and then at 3,5,10 minutes following intubation
Upon arrival in OR (baseline) then immediately following intubation (T1) and then at 3,5,10 minutes following intubation

Secondary Outcome Measures

Outcome Measure
Time Frame
Mean Blood Pressure
Time Frame: This will be measured upon arrival in OR (baseline) immediately following intubation(T1) and then at 3,5,10 minutes following intubation
This will be measured upon arrival in OR (baseline) immediately following intubation(T1) and then at 3,5,10 minutes following intubation
Systolic Blood Pressure
Time Frame: This will be measured upon arrival in OR (baseline) immediately following intubation(T1) and then at 3,5,10 minutes following intubation
This will be measured upon arrival in OR (baseline) immediately following intubation(T1) and then at 3,5,10 minutes following intubation
Diastolic Blood Pressure
Time Frame: This will be measured upon arrival in OR (baseline) immediately following intubation(T1) and then at 3,5,10 minutes following intubation
This will be measured upon arrival in OR (baseline) immediately following intubation(T1) and then at 3,5,10 minutes following intubation

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Pakistan Institute of Medical Sciences

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

December 22, 2025

Primary Completion (Actual)

May 15, 2026

Study Completion (Actual)

May 15, 2026

Study Registration Dates

First Submitted

December 21, 2025

First Submitted That Met QC Criteria

December 21, 2025

First Posted (Actual)

December 24, 2025

Study Record Updates

Last Update Posted (Actual)

May 29, 2026

Last Update Submitted That Met QC Criteria

May 27, 2026

Last Verified

May 1, 2026

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • F.5.2/2024(ERRC)/PIMS

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

IPD Plan Description

This is due to hospital and ethical committee policies

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

Yes

product manufactured in and exported from the U.S.

Yes

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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