Emergency Intestinal Anastmosis

December 22, 2025 updated by: Reham Zakaria Mohamed Ahmed, Zagazig University

A Comparative Study Between Stapled and Handsewn Intestinal Anastmosis in Emergency Laparotomy

The goal of this clinical trial is to compare the outcomes of emergency intestinal anastomosis after stapled and handsewn anastmosis. The main question it aims to answer are:

Is stapled intestinal anastmosis is better than handsewn anastmosis in emergency laparotomy?

Participants at surgical emergency unit:

  • Had intestinal anastmosis either by stapler or handsewn.
  • kept in hospital for follow up and detection of complications like wound infection and leakage.
  • Either discharged or managed according to the complications
  • Outcomes were compared between the two groups

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

90

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
    • Sharqia Province
      • Zagazig, Sharqia Province, Egypt, 44519
        • Faculty of Medicine, Zagazig University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • patients admitted to emergency surgery and needed intestinal anastmosis

Exclusion Criteria:

  • patients below 18 years old
  • immune-compromised patients e.g. corticosteroids therapy, autoimmue disease

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: stapled group
Procedure: emergency intestinal anastmosis surgery
cases with intestinal trauma, perforation or intestinal obstruction had emergency laparotomy and intestinal anastmosis was done
Active Comparator: handsewn group
Procedure: emergency intestinal anastmosis surgery
cases with intestinal trauma, perforation or intestinal obstruction had emergency laparotomy and intestinal anastmosis was done

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
intestinal leakage
Time Frame: from one day to two weeks after surgery
intestinal leakage output calculated in ml by weighing dressing or calculating the drain output
from one day to two weeks after surgery

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
operation time
Time Frame: from incision time to closure (0 to 5 hours)
operation time in minutes was calculated
from incision time to closure (0 to 5 hours)
bleeding
Time Frame: from one hour to two days after surgery
bleeding amount was calculated in ml
from one hour to two days after surgery
hospital stay
Time Frame: from one day to one month after surgery
hospital stay was recorded in days
from one day to one month after surgery
post-operative pain
Time Frame: from one to three days after after surgery
pain was evaluated by the visual analogue scale from 1 to 10. score 1 means least painful, score 10 means very painful
from one to three days after after surgery

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Zagazig University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

December 20, 2024

Primary Completion (Actual)

December 20, 2025

Study Completion (Actual)

December 20, 2025

Study Registration Dates

First Submitted

December 22, 2025

First Submitted That Met QC Criteria

December 22, 2025

First Posted (Actual)

January 7, 2026

Study Record Updates

Last Update Posted (Actual)

January 7, 2026

Last Update Submitted That Met QC Criteria

December 22, 2025

Last Verified

December 1, 2025

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 942\31-Dec-2024

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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