Comparison of Conventional Buccal Nerve Block Versus Buccal Nerve Trunk Block During Extraction of Posterior Mandibular Teeth (Buccal Trunk)

February 1, 2026 updated by: SYED SAAD AFTAB, Watim Medical & Dental College

Comparison of Conventional Buccal Nerve Block Versus Buccal Nerve Trunk Block for Anaesthesia of Buccal Mucosa During Extraction of Mandibular Posterior Teeth

This randomised control trial will compare the efficacy of conventional buccal nerve block versus buccal trunk block using visual analogue scale to evaluate pain and additional anesthesia injection during extraction of mandibular molars.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Detailed Description

Dental extraction of mandibular posterior teeth require buccal mucosa anesthesia for pain free extraction. Conventional buccal nerve block is the commonly used technique for anesthesia of buccal mucosa but often is not effective and requires multiple injections. This study aims to compare coventional buccal nerve block with buccal nerve trunk block on the basis of Efficacy of local anesthesia which will be determined by need for supplemental infiltration: Use of more than 1 anesthesia cartridges during procedure will be labelled as need for supplemental infiltration.

Intraoperative pain perception: It was assessed while giving injection and during extraction of the tooth using the visual analog scale (VAS) scores. Score of more than 4 will be labelled as positive pain perception.

Study Type

Interventional

Enrollment (Estimated)

100

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • Pakistan
    • Islamabad, Pakistan
      • Islamabad, Islamabad, Pakistan, Pakistan, 46500
        • Recruiting
        • Watim Medical College & Dental Hospital
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Patients aged 20 to 60 years
  • Patients of both gender
  • Patient requiring extraction of mandibular molars

Exclusion Criteria:

  • Pregnant women
  • Pathologies associated with teeth i.e. cysts, tumors
  • Patients on radiotherapy or chemotherapy
  • Patients with mandibular fracture

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Conventional Buccal Nerve Block for anesthesia of buccal mucosa
Administration of anesthesia using conventional buccal nerve block technique for anesthesia of buccal mucosa.
Procedure: Conventional Buccal Nerve Block
Arm Description: Administration of anesthesia at the level of occlusion lateral to last mandibular molar. Needle is inserted until bone contact is achieved. 1ml lidocaine with 1:100000 anesthesia is administered.
Experimental: Buccal Nerve Trunk Block
Administration of anesthesia at the buccal trunk 10mm above the coventional buccal nerve block for anesthesia of buccal mucosa.
Procedure: Buccal Nerve Trunk Block
Arm Description: Administration of anesthesia 10 mm above occlusal plane lateral to last mandibular molar. 1ml lidocaine with 1:100000 anesthesia is administered.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Intraoperative pain perception
Time Frame: Within 2hours of anesthesia administration
It was assessed while giving injection and during extraction of the tooth using the visual analog scale (VAS) scores. Facial pain scale uses facial expression to evaluate the amount of pain. It has scores ranging from 0 to 10 with 0 as the least pain and 10 as the worst pain. Score of more than 4 will be labelled as positive pain perception.
Within 2hours of anesthesia administration
Need for supplemental infiltration
Time Frame: Within 2 hour of initial anesthesia administration
Use of more than 1 anesthesia cartridges during procedure will be labelled as need for supplemental infiltration.
Within 2 hour of initial anesthesia administration

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Watim Medical & Dental College

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

  • 1.Risbaf-Fakoor S, Hashemzehi H, Jahantigh H, Arab K, Gholami L. Adjunctive low-level laser therapy using 980-nm diode laser after impacted mandibular third molar surgery: a randomized clinical trial. Avicenna J Clin Med. 2020; 26 (4):199-205. 2.Mahat A, Yadav R, Yadav A, Acharya P, Dongol A, Sagtani A et al. A comparative study of the effect of sutureless versus multiple sutures technique on complications following third molar surgery in Nepalese subpopulation. Int J Dent. 2020; 2020(1):1-6. 3.Sruthi MA, Ramakrishnan M. Transpapillary injection technique as a substitute for palatal infiltration: a split-mouth randomized clinical trial. Int J Clin Pediatr Dent. 2021; 14(5):640-3. 4.Decloux D, Ouanounou A. Local anaesthesia in dentistry: a review. Int Dent J. 2020; 71(2):87-95. 5.Wang YH, Wang DR, Liu JY, Pan J. Local anesthesia in oral and maxillofacial surgery: A review of current opinion. J Dent Sci. 2021; 16(4):1055-65. 6.Koyata T, Yanai C, Shionoya Y, Takasugi Y, Sunada K. Buccal nerve trunk block anesthetizes the buccal mucosa beyond the papilla of the parotid duct. J Oral Maxillofac Surg. 2023;81(3):272-9. 7.Figueiredo R, Sofos S, Soriano-Pons E, Camps-Font O, Sanmarti-Garcia G, Gay-Escoda C, Valmaseda-Castellón E. Is it possible to extract lower third molars with infiltration anaesthesia techniques using articaine? A double-blind randomized clinical trial. Acta Odontol. Scand. 2021 Jan 2;79(1):1-8.

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

March 20, 2026

Primary Completion (Estimated)

January 1, 2027

Study Completion (Estimated)

January 1, 2027

Study Registration Dates

First Submitted

December 8, 2025

First Submitted That Met QC Criteria

January 4, 2026

First Posted (Actual)

January 9, 2026

Study Record Updates

Last Update Posted (Actual)

February 4, 2026

Last Update Submitted That Met QC Criteria

February 1, 2026

Last Verified

December 1, 2025

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • WM&DCR/R&D(ERB)/2023/68

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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