Identification of Iatrogenic Drug Events Upon Admission to the Adult Emergency Departments (IATRO-URG)

Pharmacists working within a multidisciplinary team have a role to play in detecting the potential iatrogenic origin of a hospital admission, in order to implement measures to improve medication use appropriately and limit readmissions for medication-related iatrogenesis. The iatrogenic detection process depends on the individual involved, their experience, and any tools consulted. Indeed, detection aids have their place in this process and aim for better identification. For example, a questionnaire called AT HARM 10 was developed by a team of experienced pharmacists to identify hospitalizations related to medication-related iatrogenesis. The use of this tool has been validated for pharmacists as well as for pharmacy students: interns and fifth-year medical students.

Identifying iatrogenic drug events among patients presenting to the emergency department using the AT HARM 10 grid in order to intervene and adapt therapeutic management. This clinical pharmacy activity complements what is already included in routine care (medication review, pharmaceutical analysis, and pharmaceutical intervention to adapt treatment).

Study Overview

• Status: Recruiting
• Conditions: Iatrogenic Drug Events

• Study Type: Observational
• Enrollment (Estimated): 100

Contacts and Locations

• Study Contact: Name: Julia WALTHER, PharmD; Phone Number: 33 3 88 12 78 18; Email: julia.walther@chru-strasbourg.fr

Study Locations

• France
  • Strasbourg, France, 67091
    • Recruiting
    • Service de Pharmacie - Stérilisation - CHU de Strasbourg - France
    • Contact: Julia WALTHER, PharmD; Phone Number: 33 3 88 12 78 18; Email: julia.walther@chru-strasbourg.fr
    • Principal Investigator: Julia WALTHER, PharmD
    • Sub-Investigator: Elsa FORET, PharmD
    • Sub-Investigator: Etienne QUOIRIN, MD

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

Adult patient (> 65 years old) treated in the emergency department of Hautepierre Hospital and presenting a prioritization score > 7 according to the Von Korff score

Description

Inclusion Criteria:

• Adult patient (> 65 years old)
• Treated in the emergency department of Hautepierre Hospital
• Presenting a prioritization score > 7 according to the Von Korff score
• Subject (and their legal representative, if applicable) not objecting to the reuse of their data for scientific research purposes.

Exclusion Criteria:

- Presence of a written objection in the patient's medical file (and/or that of their legal representative, if applicable) to the reuse of their data for scientific research purposes

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Number of patients for whom an iatrogenic event was identified	Up to 9 months

Collaborators and Investigators

• Sponsor: University Hospital, Strasbourg, France

Study record dates

Study Major Dates

• Study Start (Actual): July 9, 2025
• Primary Completion (Estimated): May 1, 2026
• Study Completion (Estimated): May 9, 2026

Study Registration Dates

• First Submitted: December 30, 2025
• First Submitted That Met QC Criteria: December 30, 2025
• First Posted (Estimated): January 12, 2026

Study Record Updates

• Last Update Posted (Estimated): January 12, 2026
• Last Update Submitted That Met QC Criteria: December 30, 2025
• Last Verified: December 1, 2025

More Information

Terms related to this study

• Keywords: Pharmaceutical intervention; Iatrogenic drug events; Medication-related iatrogenesis
• Other Study ID Numbers: 9542

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No