LASER Effects Blood Flow (LASERBF)

January 18, 2026 updated by: Saint Paul's Hospital, Congregation Of The Sisters Of Saint Paul De Chartres

Effects of Low Power LASER on the Heart Rate Variability of Human Subjects

This study investigate the potential impact of low power laser (LPL), an non-invasive physical therapy, on the cardiovascular system by focusing on its effect on heart rate and autonomic tone.

Study will recruit healthy volunteers and non-invasively monitor their electrocardiogram and digital pulse in response to LPL.

In addition, the potential involvement of autonomic tone will be clarify by topically applying gel (2% lidocaine gel)

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Detailed Description

This study investigate the potential impact of low power laser (LPL), an non-invasive physical therapy, on the cardiovascular system by focusing on its effect on heart rate and autonomic tone.

Study will recruit healthy volunteers (age 20-60; having no diabetes, hypertension, or other medical problem) and non-invasively monitor their electrocardiogram and digital pulse in response to LPL (with an intensity for relieving pain).

In addition, the potential involvement of autonomic tone will be clarify by topically applying gel (2% lidocaine gel) at the site 2 cm distal to the applying site.

Study Type

Interventional

Enrollment (Estimated)

45

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

  • Name: Chun-Ming Hsieh, MS
  • Phone Number: 8714 +886-(03)361-3141
  • Email: tblin2@gmail.com

Study Contact Backup

  • Name: Tzer-Bin Lin, Ph.D.
  • Phone Number: +886-0935-972505

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • age from 20-45

Exclusion Criteria:

  • no medical history of diabetes, hypertension, or other medical problem

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Basic Science
  • Allocation: N/A
  • Interventional Model: Single Group Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: test effect
Control, experiment, and recovery data will be acquired for each volunteer
Other: physical therapy (low power LASER)
Low power laser with an intensity for pain relieving will be applied to volunteers

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
heart rate
Time Frame: Continuous heart rate (HR) recording will start when it is stable after a brief resting (10 min); maintained during stimulation (30 min), and lasted for a period until the HR recovers.
the heart rate before, during, and after low power LASER
Continuous heart rate (HR) recording will start when it is stable after a brief resting (10 min); maintained during stimulation (30 min), and lasted for a period until the HR recovers.

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Saint Paul's Hospital, Congregation Of The Sisters Of Saint Paul De Chartres

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

March 1, 2026

Primary Completion (Estimated)

May 30, 2026

Study Completion (Estimated)

May 30, 2026

Study Registration Dates

First Submitted

September 26, 2025

First Submitted That Met QC Criteria

January 18, 2026

First Posted (Actual)

January 27, 2026

Study Record Updates

Last Update Posted (Actual)

January 27, 2026

Last Update Submitted That Met QC Criteria

January 18, 2026

Last Verified

July 1, 2025

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • LASERBF1
  • Saint Paul's Hospital (Other Identifier: Saint Paul's Hospital)

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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