Comparison of Quadratus Lumborum Block Types in Open Gynecologic Surgery

February 1, 2026 updated by: KADİR TEOMAN, Ankara Etlik City Hospital

A Prospective Observational Comparison of Quadratus Lumborum Block Techniques in Gynecologic Surgery

This study was conducted to evaluate the effectiveness of Quadratus Lumborum Type 1 and Type 2 blocks on postoperative acute pain in gynecological operations performed with a Pfannenstiel incision.

Study Overview

Status

Completed

Conditions

Detailed Description

This prospective observational study was conducted to observe and analyze postoperative acute pain outcomes in patients undergoing open gynecologic surgery with a Pfannenstiel incision. The study included patients who received quadratus lumborum block (QLB) techniques as part of routine perioperative analgesic management.

Quadratus lumborum blocks were performed using ultrasound guidance according to standard clinical practice. The block was administered with the patient in the lateral position, and a high-frequency linear ultrasound transducer was used to identify the quadratus lumborum muscle and surrounding anatomical structures. For Quadratus Lumborum Type 1 (lateral) block, local anesthetic was injected at the anterolateral border of the quadratus lumborum muscle. For Quadratus Lumborum Type 2 (posterior) block, local anesthetic was deposited posterior to the quadratus lumborum muscle, within the thoracolumbar fascial plane.

The selection of Quadratus Lumborum Type 1 or Type 2 block was determined solely by the attending anesthesiologist based on routine clinical considerations, surgical characteristics, and patient-related factors. No intervention or regional analgesia technique was assigned by the investigators for the purpose of this study, and study participation did not influence anesthetic management. Participants would have received the same anesthetic and regional analgesia techniques in the same manner and intensity regardless of study enrollment.

Postoperative acute pain outcomes were prospectively collected and analyzed between predefined exposure groups according to the routinely applied quadratus lumborum block technique. The investigators did not modify clinical practice, dosing, timing, or performance of regional anesthesia. All anesthetic and analgesic interventions were provided as part of standard medical care.

This study was approved by the local ethics committee as an observational study and was conducted in accordance with institutional standards of care.

Study Type

Observational

Enrollment (Actual)

68

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey (Türkiye)
    • Ankara
      • Ankara, Ankara, Turkey (Türkiye), 06830
        • Ankara Etlik City Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Probability Sample

Study Population

female patients undergoing open gynecological surgery

Description

Inclusion Criteria:

  • ASA I-III
  • Female patients aged 18-80
  • Cases undergoing open myomectomy and total abdominal hysterectomy

Exclusion Criteria:

  • Those who do not want a block
  • Patients who are allergic to local anesthetics
  • Patients with coagulopathy
  • Pregnancy
  • Previous surgery in the area where the block will be applied

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Reduction of opioid requirement in patients undergoing open myomectomy and total abdominal hysterectomy
Time Frame: from april to may
It investigates the effectiveness of quadratus lumborum 1 block alone in acute pain, compared to quadratus lumborum 1 and 2 blocks applied together in patients undergoing open myomectomy and total abdominal hysterectomy.
from april to may

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
no need for additional analgesia
Time Frame: from 1 may to 15 may
the first postoperative analgesic consumption in patients undergoing open myomectomy and total abdominal hysterectomy.
from 1 may to 15 may

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Ankara Etlik City Hospital

Investigators

  • Principal Investigator: KADİR T ETİKCAN, MEDİCAL DOCTOR, Ankara Etlik City Hospital

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

April 1, 2025

Primary Completion (Actual)

April 20, 2025

Study Completion (Actual)

May 15, 2025

Study Registration Dates

First Submitted

April 19, 2025

First Submitted That Met QC Criteria

February 1, 2026

First Posted (Actual)

February 9, 2026

Study Record Updates

Last Update Posted (Actual)

February 9, 2026

Last Update Submitted That Met QC Criteria

February 1, 2026

Last Verified

February 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • AEŞH-EK1-2025-068

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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