- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07438431
Comparison of the Effects of Kinesio Taping and Graston Application in Individuals With Delayed Onset Muscle Soreness
February 27, 2026 updated by: Mustafa Can Salamci, Gazi University
Comparison of the Effects of Kinesio Taping and Graston Application on Muscle Oxygenation, Functional Muscle Strength, and Reaction Time in Individuals With Delayed Onset Muscle Soreness
Delayed onset muscle soreness (DOMS) is the pain, stiffness, and discomfort that usually appear 24-72 hours after doing an unusual or intense physical activity.
Previous studies have shown that both Kinesio taping and the Graston technique can help reduce this type of muscle soreness.
However, it is not clear which method is more effective, and their effects on muscle oxygen levels, muscle strength during functional tasks, and reaction time have not been compared directly.
The aim of this study was to compare these two treatment methods in people who developed DOMS.
A total of 30 healthy participants took part in the study.
One group received Kinesio taping, the second group received the Graston technique, and the third group did not receive any treatment and was left to recover naturally.
Muscle oxygen levels, functional muscle strength, and reaction times were measured before exercise and again 48 hours later, and the results were compared.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Detailed Description
Delayed onset muscle soreness (DOMS) is characterized by increasing pain, discomfort, and stiffness occurring within 24-72 hours after unaccustomed physical activity.
Previous studies have shown that both Kinesio taping (KT) and the Graston technique are effective in reducing DOMS; however, their comparative superiority has not been investigated, and their effects on muscle oxygenation, functional muscle strength, and reaction time have not been directly compared.
The aim of this study was to compare the effects of Kinesio taping and the Graston technique on muscle oxygenation, functional muscle strength, and reaction time in individuals with induced DOMS.
A total of 30 healthy participants were included in the study; Kinesio taping was applied to the first group, the Graston technique to the second group, and the third group served as a control and was allowed to recover naturally.
Physical activity levels, muscle oxygenation, functional muscle strength, and reaction times were measured before exercise and at the 48th hour, and the obtained data were statistically compared.
Study Type
Interventional
Enrollment (Actual)
20
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Please Select
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Ankara, Please Select, Turkey (Türkiye), 06490
- Gazi University
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Adult
Accepts Healthy Volunteers
Yes
Description
Inclusion Criteria:
- Being between 18 and 30 years of age
- Being classified as inactive according to the International Physical Activity Questionnaire
- Having a body mass index below 25
Exclusion Criteria:
- Presence of a chronic disease
- History of lower extremity orthopedic disorders or surgery
- Current lower extremity muscle pain
- History of lower extremity trauma within the last month
- Use of medications that may affect the musculoskeletal system (e.g., muscle relaxants, anti-inflammatory drugs)
- Caffeine consumption within 24 hours before exercise
- Participation in another exercise or intense physical activity within 24 hours before the test
- Use of performance-enhancing supplements
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
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Active Comparator: Kinesio Taping
The group of individuals who will undergo kinesio taping application.
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In this study, the lymphatic application technique of Kinesio taping was used.
Two Kinesio tapes, each 5 cm in width, were applied over the quadriceps femoris muscle.
After measuring the length over the muscle, the tape was cut to the appropriate size and shaped for lymphatic application.
The central portion of the tape and five longitudinal strips extending from this part were created.
The central portion was applied without tension, while the strips were applied to the skin with approximately 15% tension.
The ends of the strips were again applied without tension.
The five strips were arranged in a fan-cut (octopus-like) configuration.
The application was performed while the participant was lying in the supine position with the muscle in a relaxed state.
The central part of the tape was placed near the inguinal lymph nodes.
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Experimental: Graston Technique
The group of individuals who will undergo Graston technique application.
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The Graston massage technique is a form of manual therapy performed with stainless steel instruments and a lubricating oil instead of using the hands.
For the application, a smooth metal planor head was used.
The participant lay in the supine position, and baby oil was applied to the quadriceps femoris muscle.
The convex side of the Graston instrument was then applied sequentially to the vastus lateralis, rectus femoris, and vastus medialis muscles, for 2 minutes on each muscle, moving from the cranial to the caudal direction, for a total of 6 minutes.
The massage was performed twice: immediately after exercise and again on the following day.
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No Intervention: Control
spontaneous recovery process
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
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Muscle Oxygenation
Time Frame: 48 hours
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Muscle oxygenation was measured using the FYER near-infrared spectroscopy (NIRS) device manufactured by Train.Red.
The FYER device is a stable system capable of accurately measuring changes in total tissue hemoglobin and tissue oxygenation, and its validity and reliability have been previously established.
The device was secured over the muscle using the strap provided in the package and fixed onto the target muscle of the limb.
Muscle oxygenation of the quadriceps femoris was recorded during the squat exercise.
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48 hours
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Reaction Time
Time Frame: 48 hours
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Lower extremity reaction time was measured using the BlazePod Trainer device (Play Coyotta Ltd., Tel Aviv, Israel).
The BlazePod is a system designed to assess dynamic reaction time.
After a waiting period, the device emits a light stimulus and the timer starts.
When the participant touches the device with a body part, the light turns off and the timer stops.
The elapsed time provides a quantitative measure of reaction time.
The device has been shown to be a valid and reliable tool for reaction time assessment.
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48 hours
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Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
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Visual Analog Scale
Time Frame: 48 hours
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The Visual Analog Scale is a simple tool used to convert subjective experiences into numerical values.
It consists of a 100-mm line with two endpoints representing the extremes of the parameter being measured.
For pain assessment, one end indicates "no pain," and the other indicates "very severe pain."
The participant marks the point on the line that best reflects their current pain level, and the distance from the "no pain" end to the marked point represents the pain intensity.
The VAS is one of the most commonly used tools for assessing musculoskeletal pain and has been shown to be a valid and reliable measurement method.
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48 hours
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Assessment of Functional Muscle Strength
Time Frame: 48 hours
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unctional muscle strength was evaluated using the K-Invent® K-Force force platform, a valid and reliable measurement device.
Strength was assessed during a squat exercise.
While standing on the force platform, participants were instructed to perform squats to approximately 90-100 degrees of knee flexion.
Three measurements were taken, and participants were asked to perform as many repetitions as possible during each 10-second test period.
A 60-second rest interval was provided between measurements.
The number of repetitions, maximum force, and right-left limb asymmetry were recorded.
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48 hours
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Assessment of Edema
Time Frame: 48 hours
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Thigh circumference was measured as an indirect indicator of edema.
The midpoint of the thigh was defined at the level of the greater trochanter.
A measuring tape was used to obtain the thigh circumference while the participant lay in the supine anatomical position.
The measurement was recorded in centimeters.
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48 hours
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Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
General Publications
- Heiss R, Lutter C, Freiwald J, Hoppe MW, Grim C, Poettgen K, Forst R, Bloch W, Huttel M, Hotfiel T. Advances in Delayed-Onset Muscle Soreness (DOMS) - Part II: Treatment and Prevention. Sportverletz Sportschaden. 2019 Mar;33(1):21-29. doi: 10.1055/a-0810-3516. Epub 2019 Mar 13.
- Stanek J, Sullivan T, Davis S. Comparison of Compressive Myofascial Release and the Graston Technique for Improving Ankle-Dorsiflexion Range of Motion. J Athl Train. 2018 Feb;53(2):160-167. doi: 10.4085/1062-6050-386-16. Epub 2018 Jan 26.
- Song W, Yang Y. Effect of Kinesio taping on delayed-onset muscle soreness in elite athletes. J Sports Med Phys Fitness. 2022 May;62(5):667-672. doi: 10.23736/S0022-4707.21.12280-7. Epub 2021 Mar 26.
- Camacho MA, Herrera E, Barela JA, Delgado-Diaz DC. Kinesiotaping Diminishes Delayed Muscle Soreness but does not Improve Muscular Performance. Int J Sports Med. 2020 Aug;41(9):596-602. doi: 10.1055/a-1088-5223. Epub 2020 May 12.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
June 1, 2024
Primary Completion (Actual)
June 1, 2025
Study Completion (Actual)
June 1, 2025
Study Registration Dates
First Submitted
February 18, 2026
First Submitted That Met QC Criteria
February 23, 2026
First Posted (Actual)
February 27, 2026
Study Record Updates
Last Update Posted (Actual)
March 2, 2026
Last Update Submitted That Met QC Criteria
February 27, 2026
Last Verified
February 1, 2026
More Information
Terms related to this study
Keywords
Other Study ID Numbers
- 2024 - 635
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
UNDECIDED
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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