- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07439198
The Influence of Water Intake on Food Intake at Meals Varying in Moisture (WaterxMoisture)
April 21, 2026 updated by: Cornell University
The primary purpose of this study is to investigate the influence of including water as a beverage at a meal on food intake, and if the influence of water consumption on food consumption is moderated by switching behavior.
Additionally, other individual characteristics will be examined for their influence on the effects of simultaneous variety and portion size on meal intake.
Study Overview
Status
Recruiting
Conditions
Intervention / Treatment
Study Type
Interventional
Enrollment (Estimated)
60
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Contact
- Name: Paige M Cunningham, PhD
- Phone Number: 607-255-2650
- Email: pmc242@cornell.edu
Study Locations
-
-
New York
-
Ithaca, New York, United States, 14850
- Recruiting
- Cornell University
-
Contact:
- Paige M Cunningham, PhD
- Phone Number: 607-255-2650
- Email: pmc242@cornell.edu
-
Principal Investigator:
- Paige M Cunningham, PhD
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Adult
Accepts Healthy Volunteers
No
Description
Inclusion Criteria:
- 20 - 60 years old
- Regularly consume 3 meals per day
- Like, are willing to eat, and do not have restrictions or allergies to the study foods
- Are willing to refrain from drinking alcohol the day before study visits
- Are willing to consume a consistent breakfast the day of study visits
- Have a BMI between 20-29.9 kg/m2
Exclusion Criteria:
- Experienced a weight change >5 kg in the past month
- Are a smoker
- Are an athlete in training
- Take medications or have a health condition known to affect taste, smell, thirst, or appetite
- Are pregnant or breastfeeding
- Have ever been diagnosed with an eating disorder or depression
- Specialize in the fields of psychology or nutritional sciences
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Basic Science
- Allocation: Randomized
- Interventional Model: Crossover Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: No Water, Low Moisture
No water served with the meal, the food will be low in moisture
|
No water will be served with the meal
A low moisture food will be served
|
|
Experimental: No Water, High Moisture
No water served with the meal, the food will be high in moisture
|
No water will be served with the meal
A high moisture food will be served
|
|
Experimental: Water, Low Moisture
Water will be served with the meal, the food will be low in moisture
|
A low moisture food will be served
Water will be served with the meal
|
|
Experimental: Water, High Moisture
Water will be served with the meal, the food will be high in moisture
|
A high moisture food will be served
Water will be served with the meal
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Change in food intake
Time Frame: Weeks 1, 2, 3, 4
|
Weight (grams) of the food consumed
|
Weeks 1, 2, 3, 4
|
|
Change in energy intake
Time Frame: Weeks 1, 2, 3, 4
|
Energy (kcal) of the food consumed
|
Weeks 1, 2, 3, 4
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Change in bite count
Time Frame: Weeks 1, 2, 3, 4
|
The number of bites of food during the meal
|
Weeks 1, 2, 3, 4
|
|
Change in sip count
Time Frame: Weeks 1, 2, 3, 4
|
The number of sips of water during the meal
|
Weeks 1, 2, 3, 4
|
|
Change in switching between bites and sips
Time Frame: Weeks 1, 2, 3, 4
|
The number of switches between bites and sips during the meal
|
Weeks 1, 2, 3, 4
|
|
Change in rating of hunger
Time Frame: From before the test meal to after the test meal in weeks 1, 2, 3, 4
|
Measured on a 100-mm visual analogue scale ranging from not at all hungry (0 mm) to extremely hungry (100 mm)
|
From before the test meal to after the test meal in weeks 1, 2, 3, 4
|
|
Change in rating of thirst
Time Frame: From before the test meal to after the test meal in weeks 1, 2, 3, 4
|
Measured on a 100-mm visual analogue scale ranging from not at all thirsty (0 mm) to extremely thirsty (100 mm)
|
From before the test meal to after the test meal in weeks 1, 2, 3, 4
|
|
Change in rating of fullness
Time Frame: From before the test meal to after the test meal in weeks 1, 2, 3, 4
|
Measured on a 100-mm visual analogue scale ranging from not at all full (0 mm) to extremely full (100 mm)
|
From before the test meal to after the test meal in weeks 1, 2, 3, 4
|
|
Change in meal duration
Time Frame: Weeks 1, 2, 3, 4
|
Duration of the meal in minutes
|
Weeks 1, 2, 3, 4
|
|
Change in rating of pleasantness of the taste of food samples
Time Frame: From before the test meal to after the test meal in weeks 1, 2, 3, 4
|
Measured on a 100-mm visual analogue scale ranging from not at all pleasant (0 mm) to extremely pleasant (100 mm).
This will be used to calculate Sensory-Specific Satiety
|
From before the test meal to after the test meal in weeks 1, 2, 3, 4
|
|
Change in rating of desire to eat food samples
Time Frame: From before the test meal to after the test meal in weeks 1, 2, 3, 4
|
Measured on a 100-mm visual analogue scale ranging from not at all strong (0 mm) to extremely strong (100 mm), in answer to "How strong is your desire to eat [this food] right now?".
This will be used to calculate Sensory-Specific Satiety.
|
From before the test meal to after the test meal in weeks 1, 2, 3, 4
|
|
Change in rating of nausea
Time Frame: From before the test meal to after the test meal in weeks 1, 2, 3, 4
|
Measured on a 100-mm visual analogue scale ranging from not at all nauseated (0 mm) to extremely nauseated (100 mm)
|
From before the test meal to after the test meal in weeks 1, 2, 3, 4
|
|
Change in rating of prospective consumption
Time Frame: From before the test meal to after the test meal in weeks 1, 2, 3, 4
|
Measured on a 100-mm visual analogue scale ranging from nothing at all (0 mm) to a large amount (100 mm), in answer to "How much food do you think you could eat right now?".
|
From before the test meal to after the test meal in weeks 1, 2, 3, 4
|
|
Change in water intake
Time Frame: Weeks 1, 2, 3, 4
|
Weight (grams) of water consumed
|
Weeks 1, 2, 3, 4
|
|
Change in eating rate
Time Frame: Weeks 1, 2, 3, 4
|
Mean food intake per minute (grams/minute), calculated by dividing meal food intake by meal duration
|
Weeks 1, 2, 3, 4
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
March 15, 2026
Primary Completion (Estimated)
February 23, 2027
Study Completion (Estimated)
February 23, 2027
Study Registration Dates
First Submitted
January 16, 2026
First Submitted That Met QC Criteria
February 23, 2026
First Posted (Actual)
February 27, 2026
Study Record Updates
Last Update Posted (Actual)
April 23, 2026
Last Update Submitted That Met QC Criteria
April 21, 2026
Last Verified
April 1, 2026
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- IRB0150494
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
NO
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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