Preoperative Cardiac Power Output and P-POSSUM Score

Investigation of the Relationship Between Preoperative Cardiac Power Output and P-POSSUM Score

This study aims to investigate the relationship between preoperative Cardiac Power Output (CPO), which reflects the pumping capacity of the heart, and the P-POSSUM score, a widely used surgical risk assessment tool, in patients aged 65 years and older undergoing abdominal surgery. Simple and non-invasive measurements performed in the preoperative period will be used to obtain CPO values and to evaluate whether these measurements are helpful in predicting postoperative morbidity and mortality. No additional procedures beyond routine clinical care will be performed as part of this observational study. The findings of this study may contribute to a more accurate assessment of surgical risk and help improve patient safety in the perioperative period.

Study Overview

• Status: Recruiting
• Conditions: Postoperative Mortality; Postoperative Morbidity; Surgical Risk Assessment

Detailed Description

This is a prospective, observational study designed to evaluate the relationship between preoperative Cardiac Power Output (CPO) and the P-POSSUM risk score in patients aged 65 years and older undergoing abdominal surgery, including both elective and emergency procedures. CPO is a hemodynamic parameter reflecting overall cardiac pumping power and may provide additional physiologic information beyond traditional risk models. P-POSSUM is widely used to estimate postoperative morbidity and mortality based on physiological and operative variables.

Eligible patients will be assessed in the preoperative period. Preoperative CPO will be obtained using non-invasive hemodynamic measurements as part of routine perioperative practice. The P-POSSUM score will be calculated for each patient using standard definitions. Patients will be followed during the postoperative period to document clinical outcomes, including postoperative complications and mortality within the predefined follow-up window, as well as length of hospital stay when available.

The primary objective is to assess the association between preoperative CPO and the P-POSSUM score. Secondary objectives include exploring whether preoperative CPO is associated with postoperative outcomes and whether it may help refine perioperative risk stratification. This study does not involve any investigational treatment; no additional interventions beyond standard clinical care will be performed. All data will be handled in accordance with applicable privacy and confidentiality regulations, and patient identifiers will not be included in the analysis dataset.

• Study Type: Observational
• Enrollment (Estimated): 120

Contacts and Locations

• Study Contact: Name: Engin Kılınç, medical doctor; Phone Number: 00 90 332 223 60 00; Email: enginkilinc96@gmail.com

Study Locations

• Turkey (Türkiye)
  • Konya, Turkey (Türkiye)
    • Recruiting
    • Necmettin Erbakan University
    • Contact: Engin Kılınç, medical doctor; Phone Number: 00 90 332 223 60 00; Email: enginkilinc96@gmail.com

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

This study will include patients aged 65 and over who are scheduled for abdominal surgery at Necmettin Erbakan University Faculty of Medicine Hospital.

Description

Inclusion Criteria: Being 65 years of age or older,

• Undergoing abdominal surgery in general surgery practice (including elective and emergency procedures),
• ASA (American Society of Anesthesiologists) class I-III,
• Adequate recording with transthoracic echocardiography,
• Having given informed consent.

Exclusion Criteria:Advanced heart failure with ejection fraction (EF) <30%,

• Severe valvular disease (severe stenosis or insufficiency),
• Unstable coronary artery disease or recent myocardial infarction (within the last 3 months),
• Pulmonary hypertension,
• Severe arrhythmia (uncontrolled atrial fibrillation, ventricular tachycardia, etc.)

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort

patients aged 65 years and older undergoing abdominal surgery; This cohort consists of patients aged 65 years and older undergoing abdominal surgery, including both elective and emergency procedures. All participants will undergo preoperative evaluation, including non-invasive measurement of Cardiac Power Output (CPO) and calculation of the P-POSSUM score, as part of routine clinical assessment. No experimental intervention will be performed in this study, and all patients will receive standard clinical care and follow-up. Postoperative clinical outcomes will be recorded prospectively.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
30-day postoperative mortality	All-cause mortality occurring within 30 days after abdominal surgery in patients aged 65 years and older (yes/no).	Up to 30 days after surgery

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Postoperative morbidity	Postoperative morbidity assessed using the Postoperative Morbidity Survey (POMS).	Up to 30 days after surgery
Early postoperative morbidity	Early postoperative morbidity assessed using the Postoperative Morbidity Survey (POMS) on postoperative day 3.	Postoperative day 3

Collaborators and Investigators

• Sponsor: Necmettin Erbakan University
• Investigators: Principal Investigator: ŞULE ARICAN, Assoc. Prof., Konya Necmettin Erbakan University; Study Director: Engin Kılınç, Medical Doctor, Konya Necmettin Erbakan University

Study record dates

Study Major Dates

• Study Start (Actual): March 10, 2026
• Primary Completion (Estimated): September 1, 2026
• Study Completion (Estimated): November 30, 2026

Study Registration Dates

• First Submitted: February 25, 2026
• First Submitted That Met QC Criteria: March 3, 2026
• First Posted (Actual): March 6, 2026

Study Record Updates

• Last Update Posted (Actual): March 23, 2026
• Last Update Submitted That Met QC Criteria: March 18, 2026
• Last Verified: March 1, 2026

More Information

Terms related to this study

• Keywords: cardiac power output; p-possum score
• Other Study ID Numbers: 2025/5880

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No