- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07468981
Movement Quality and Mechanical Properties of the Muscle
Association Between Movement Quality and Passive Mechanical Properties of Skeletal Muscle in Healthy Adults
Movement quality is considered a comprehensive indicator of neuromuscular control, segmental stability, and efficient force transmission, and is recognized as an important determinant of musculoskeletal health and functional performance. Optimal movement patterns help distribute joint loading appropriately, whereas suboptimal movement strategies may contribute to increased biomechanical stress and the development of overuse injuries over time. In recent years, the passive mechanical properties of muscle (stiffness, tone, and elasticity) have been suggested to influence segmental stability and movement control; however, the relationship between these variables has not been sufficiently investigated in healthy populations. The aim of this study is to examine the association between movement quality and the passive mechanical properties of skeletal muscle in healthy adults.
Healthy adult individuals will be included in the study. The sample size was determined based on a priori power analysis, and a total of 42 participants will be recruited. Movement quality will be assessed using the Functional Movement Screen (FMS). The FMS is a standardized screening tool consisting of seven fundamental movement tasks designed to evaluate basic movement patterns. Each task will be scored on a scale from 0 to 3, and the total score (0-21 points) will be used as an indicator of overall movement quality. The passive mechanical properties of muscle (stiffness, tone, and elasticity) will be measured using a portable and non-invasive device, the MyotonPRO 5, from the quadriceps, hamstring, gastrocnemius, tibialis anterior, and erector spinae muscles. Measurements will be performed at standardized anatomical reference points with the muscle in a relaxed position. The device probe will be placed perpendicular to the skin surface over the muscle, and the passive viscoelastic response of the tissue will be recorded. The relationship between variables will be analyzed using Pearson or Spearman correlation analysis, depending on data distribution characteristics.
Study Overview
Status
Conditions
Intervention / Treatment
Study Type
Enrollment (Actual)
Contacts and Locations
Study Locations
-
-
Bor
-
Niğde, Bor, Turkey (Türkiye)
- Faculty of Health Sciences
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Adult
Accepts Healthy Volunteers
Sampling Method
Study Population
Description
Inclusion Criteria:
- Female and male participants aged 18-40
- Inactive individuals according to IPAQ Physical Activity Level
- Individuals who volunteered to participate in the study
Exclusion Criteria:
- Individuals who exercise and play sports regularly
- Individuals with a history of surgery within the last 6 months
- Individuals with active pain
Study Plan
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Functional Movement Screen
Time Frame: From enrollment to the end of evaluation at 4 weeks
|
Movement quality will be assessed using FMS.
There are a total of 7 subtests.
These consist of basic movement patterns performed using body weight.
Movement quality will be scored by the researchers.
In the test, the minimum score is 0 and the maximum is 21, and an increase in the score reflects an increase in the quality of the movement.
|
From enrollment to the end of evaluation at 4 weeks
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Muscle Viscoelasticity
Time Frame: rom enrollment to the end of assesment at 4 weeks
|
The passive mechanical properties of the muscle will be measured with the MyotonPro device.
It is a non-invasive procedure.
The device's probe is placed on the skin at a right angle, and the tissue's response is recorded by the device.
|
rom enrollment to the end of assesment at 4 weeks
|
Collaborators and Investigators
Sponsor
Investigators
- Study Director: Rabia Zorlular, PhD, Nigde Omer Halisdemir University
Publications and helpful links
General Publications
- Lee, Y., Kim, M., & Lee, H. (2021). The measurement of stiffness for major muscles with shear wave elastography and myoton: a quantitative analysis study. Diagnostics, 11(3), 524.
- Cook, G., Burton, L., Hoogenboom, B. J., & Voight, M. (2014). Functional movement screening: the use of fundamental movements as an assessment of function-part 1. International journal of sports physical therapy, 9(3), 396.
- Kalkhoven, J. T., & Watsford, M. L. (2018). The relationship between mechanical stiffness and athletic performance markers in sub-elite footballers. Journal of sports sciences, 36(9), 1022-1029.
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Estimated)
Study Completion (Estimated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Other Study ID Numbers
- FMS
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Health Adult Subjects
-
ZHANG JiaqiRecruitingHealth Adult SubjectsChina
-
Nanjing Nutrabuilding Bio-tech Co., Ltd.Biofortis, Merieux NutriSciencesNot yet recruitingHealth Adult SubjectsUnited States
-
Shanghai Henlius BiotechNot yet recruitingHealth Adult SubjectsChina
-
Biotech Pharmaceutical Co., Ltd.Not yet recruiting
-
Genrix (Shanghai) Biopharmaceutical Co., Ltd.RecruitingHealth Adult SubjectsChina
-
Colgate PalmoliveCompletedHealth Adult SubjectsUnited States
-
Poznan University of Physical EducationCompletedHealth Adult SubjectsPoland
-
BiogenCelerion; Q2 SolutionsCompleted
-
Universidade Nova de LisboaNot yet recruitingImpact of a Wheat-based Fermented Beverage on Microbiota and Metabolic Health in Healthy IndividualsHealth Adult SubjectsPortugal
Clinical Trials on Healthy Subjects
-
Centre Hospitalier Universitaire Saint PierreUnknownDynamic HyperinflationBelgium
-
Nadia Bouzidi, PhDUnknown
-
Istituto Auxologico ItalianoCompletedMultiple Sclerosis | Cerebral Palsy | Parkinson Disease | Amputation | Poststroke/CVA HemiparesisItaly
-
Hospices Civils de LyonCompleted
-
Buddhist Tzu Chi General HospitalCompletedIrritable Bowel Syndrome | Functional Gastrointestinal Disorders | Healthy Subjects | Laryngopharyngeal RefluxTaiwan
-
Oregon Health and Science UniversityCompleted
-
Massachusetts General HospitalMassachusetts Eye and Ear InfirmaryCompleted
-
University Hospital, Basel, SwitzerlandSwiss National Science FoundationRecruitingMultiple Sclerosis (MS) | Relapsing-remitting Multiple Sclerosis (RRMS) | Secondary-progressive Multiple Sclerosis (SPMS) | Primary Progressive Multiple Sclerosis (PPMS)Switzerland
-
International Agency for Research on CancerFederico II University; Imperial College London; Fondazione IRCCS Istituto Nazionale... and other collaboratorsCompleted
-
Federal University of São PauloFundação de Amparo à Pesquisa do Estado de São PauloCompletedAttention Deficit Disorder With HyperactivityBrazil