Video-EEG Features of Adult Patients With Psychogenic Nonepileptic Seizures

April 7, 2026 updated by: Saglik Bilimleri Universitesi

Retrospective Analysis of Video-EEG Findings and Clinical Characteristics in Adult Patients With Psychogenic Nonepileptic Seizures

This completed retrospective observational study evaluated adult patients diagnosed with psychogenic nonepileptic seizures (PNES) who underwent video-EEG monitoring. Video-EEG records and clinical data of 50 adult patients were reviewed to describe semiological, electroclinical, and demographic characteristics of PNES. The study aimed to improve the understanding of video-EEG findings in PNES and to support accurate diagnosis in clinical practice.

Study Overview

Status

Completed

Conditions

Detailed Description

Psychogenic nonepileptic seizures (PNES) are paroxysmal events that resemble epileptic seizures but are not associated with ictal epileptiform activity on EEG. Video-EEG monitoring is considered the reference standard for diagnosis. In this retrospective observational study, video-EEG recordings and clinical files of 50 adult patients with PNES were reviewed after completion of clinical care. Demographic data, clinical presentation, and video-EEG characteristics were analyzed descriptively. No intervention was assigned as part of the study. The purpose was to characterize the video-EEG and clinical profile of adult PNES patients evaluated in routine practice.

Study Type

Observational

Enrollment (Actual)

50

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey (Türkiye)
      • Izmir, Turkey (Türkiye)
        • Saglik Bilimleri University Izmir Faculty of Medicine Department of Neurology

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

Adult patients diagnosed with psychogenic nonepileptic seizures (PNES) who underwent video-EEG monitoring.

Description

Inclusion Criteria:

  • Adults aged 18 years and older

Diagnosis of psychogenic nonepileptic seizures based on video-EEG evaluation

Availability of complete video-EEG recordings and relevant clinical records for review

Exclusion Criteria:

  • Patients younger than 18 years

Inadequate or incomplete video-EEG data

Patients with insufficient clinical documentation for retrospective evaluation

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Semiological subtype of PNES events
Time Frame: Baseline retrospective chart and video-EEG review
Classification of PNES events recorded during video-EEG monitoring into semiological clusters (pauci-kinetic, hyperkinetic, hyperventilation-eye closure) based on ictal features.
Baseline retrospective chart and video-EEG review

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Presence/absence of some events during PNES events
Time Frame: Baseline
Eye closure during PNES events Hyperventilation during PNES events Hyperkinetic motor activity Axial extension Pelvic thrusting
Baseline

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Saglik Bilimleri Universitesi

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 1, 2026

Primary Completion (Actual)

March 1, 2026

Study Completion (Actual)

March 1, 2026

Study Registration Dates

First Submitted

March 10, 2026

First Submitted That Met QC Criteria

April 7, 2026

First Posted (Actual)

April 13, 2026

Study Record Updates

Last Update Posted (Actual)

April 13, 2026

Last Update Submitted That Met QC Criteria

April 7, 2026

Last Verified

March 1, 2026

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2026/02-17

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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