Intraoral Scan and CBCT-Aided Diagnosis of Dental Plaque and Caries

Intra Oral Scan and CBCT Aided Diagnosis of Dental Plaque and Caries

This prospective clinical study aims to evaluate the diagnostic accuracy of intraoral scans (IOS) for the detection of dental plaque and caries. The diagnostic performance of IOS will be compared with current clinical reference standards. For plaque assessment, IOS-based evaluation will be compared with plaque detection using disclosing agents. For caries detection, IOS (including white-light imaging and caries detection features) will be compared with conventional visual inspection and bitewing radiography. Adult patients aged 18 to 70 years will be included.

Study Overview

• Status: Recruiting
• Conditions: Dental Caries; Dental Plaque
• Intervention / Treatment: Diagnostic test: intraoral scan

• Study Type: Observational
• Enrollment (Estimated): 50

Contacts and Locations

• Study Contact: Name: sachiko maemoto; Phone Number: +32 93 32 40 57; Email: Sachiko.Maemoto@ugent.be

Study Locations

• Belgium
  • Botestraat
    • Wondelgem, Botestraat, Belgium, 104
      • Recruiting
      • Tandarts Praktijk VERVACK

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: Yes

• Sampling Method: Non-Probability Sample

Study Population

Adult patients aged 18 to 70 years undergoing intraoral examination in a clinical setting, with at least 20 teeth, who are not pregnant and able to provide informed consent.

Description

Inclusion Criteria:

• Adults aged 18 to 70 years
• Not pregnant and not planning pregnant
• At least 20 teeth present
• Ability to provide informed consent

Exclusion Criteria:

• Conditions that prevent proper intraoral examination (e.g., severe gag reflex, limited mouth opening)
• patient unable to provide informed consent

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Study Participants; All participants undergo intraoral scanning, visual inspection, plaque disclosure, and bitewing radiography for the assessment of dental plaque and caries.	Diagnostic test: intraoral scan; intraoral scanning used for assessment of dental plaque and caries.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Diagnostic Accuracy of Intraoral Scan for Dental Plaque Detection	Diagnostic accuracy of intraoral scan compared with plaque assessment using disclosing agents.	At baseline and 2 weeks

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Agreement Between Intraoral Scan and Reference Standard for Dental Caries Detection	Agreement between intraoral scan assessments and reference standard (visual inspection and bitewing radiography) using kappa statistics.	At baseline and 2 weeks

Collaborators and Investigators

• Sponsor: University Ghent

Study record dates

Study Major Dates

• Study Start (Actual): April 3, 2025
• Primary Completion (Estimated): October 1, 2026
• Study Completion (Estimated): July 1, 2027

Study Registration Dates

• First Submitted: April 21, 2026
• First Submitted That Met QC Criteria: April 21, 2026
• First Posted (Actual): April 29, 2026

Study Record Updates

• Last Update Posted (Actual): April 29, 2026
• Last Update Submitted That Met QC Criteria: April 21, 2026
• Last Verified: April 1, 2026

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Stomatognathic Diseases; Tooth Diseases; Dental Deposits; Tooth Demineralization; Dental Plaque; Dental Caries
• Other Study ID Numbers: ONZ-2024-0383