Clinical Trials on Atherosclerotic Cardiovascular Disease (ASCVD) in Ireland

Total 1110 results

Eli Lilly and Company

Recruiting

A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

Elevated Lp(a) | Atherosclerotic Cardiovascular Disease (ASCVD)

Taiwan, United States, Spain, Argentina, China, Italy, Australia, France, Canada, Japan, Belgium, Denmark, Germany, Hungary, Israel, Austria, Korea, Republic of, Brazil, Mexico, Netherlands, Romania, United Kingdom, Greece, Czechia, India, Slovak... and more
The Medicines Company

Completed

Inclisiran for Participants With Atherosclerotic Cardiovascular Disease and Elevated Low-density Lipoprotein Cholesterol (ORION-10)

Elevated Cholesterol | ASCVD

United States
NewAmsterdam Pharma
Monash University

Recruiting

Cardiovascular Outcome Study to Evaluate the Effect of Obicetrapib in Patients With Cardiovascular Disease (PREVAIL)

Atherosclerotic Cardiovascular Disease

United States, Israel, Italy, Spain, Canada, Czechia, Poland, China, Denmark, Netherlands, Finland, Japan, Australia, Hungary, Germany, Croatia, United Kingdom, Bulgaria, South Africa, Georgia, Jordan, Slovakia, Latvia
Amgen
Duke Clinical Research Institute

Terminated

The Cardiovascular Multi-dimensional Observational Investigation of the Use of PCSK9 Inhibitors (cvMOBIUS) (cvMOBIUS)

ASCVD

United States, Canada
Amgen

Active, not recruiting

Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction (OCEAN(a)) - Outcomes Trial

Atherosclerotic Cardiovascular Disease

United States, Belgium, Spain, China, Korea, Republic of, Australia, Netherlands, Austria, Czechia, Taiwan, Italy, Portugal, Greece, Hong Kong, Hungary, United Kingdom, France, Bulgaria, Germany, Finland, Japan, Sweden, Canada, Denmark, Icelan... and more
Amgen

Completed

A Cross-sectional Study of Lipoprotein(a) Levels in Patients With Documented History of Atherosclerotic Cardiovascular Disease (ASCVD)

Atherosclerotic Cardiovascular Disease

Canada, United States, Belgium, Spain, China, Korea, Republic of, Australia, Netherlands, Austria, Czechia, Taiwan, Hungary, Italy, Portugal, United Kingdom, Greece, Hong Kong, Turkey, France, Bulgaria, Germany, Finland, Japan, Sweden, ... and more
Novartis Pharmaceuticals

Recruiting

A Study of Inclisiran to Prevent Cardiovascular Events in High-risk Primary Prevention Patients.

Primary Prevention of Atherosclerotic Cardiovascular Disease

United States, China, Italy, Spain, Canada, France, Netherlands, Switzerland, Taiwan, Greece, Thailand, Brazil, India, Hungary, Latvia, Mexico, Israel, Turkey, Argentina, Singapore, Australia, Belgium, Bulgaria, Denmark, Croatia, South Africa and more
Novartis Pharmaceuticals

Active, not recruiting

Study of Inclisiran to Prevent Cardiovascular (CV) Events in Participants With Established Cardiovascular Disease (VICTORION-2P)

Atherosclerotic Cardiovascular Disease

United States, China, South Africa, Spain, Austria, Belgium, Croatia, Estonia, Hungary, Taiwan, Turkey, Netherlands, Italy, Australia, Czechia, Denmark, France, Israel, Korea, Republic of, Thailand, Argentina, Bulgaria, Greece, Romania, Sloveni... and more
University Hospital of Limerick
University of Limerick

Recruiting

The Mechanical Characterisation of Human Saphenous and Popliteal Vein

Peripheral Vascular Diseases

Ireland
AstraZeneca
The Cleveland Clinic; IQVIA RDS Inc.

Completed

Outcomes Study to Assess STatin Residual Risk Reduction With EpaNova in HiGh CV Risk PatienTs With Hypertriglyceridemia (STRENGTH)

Eligible Men or Women Considered High Risk for Atherosclerotic Cardiovascular Disease (CVD)

United States, Belgium, Italy, Netherlands, Denmark, Taiwan, Poland, Russian Federation, Korea, Republic of, Hungary, United Kingdom, China, New Zealand, Czechia, Australia, South Africa, Ukraine, Japan, Canada, Mexico, Lithuania, Estoni...
Western Vascular Institute, Ireland

Recruiting

Lifestyle Modification Programme for Patients With Peripheral Arterial Disease

Peripheral Arterial Occlusive Disease

Ireland
National Institute for Prevention and Cardiovascular...

Recruiting

RESPONSE-2-PAD to Reduce Sedentary Time in Peripheral Arterial Disease Patients

Peripheral Arterial Disease | Peripheral Arterial Occlusive Disease | Sedentary Behavior | Sedentary Time

Ireland
Hoffmann-La Roche

Unknown

A Prospective Study to Assess the Screening Value of N-terminal Pro-B-type Natriuretic Peptide (NT-proBNP) for the Identification of Patients That Benefit From Additional Cardiac Testing Prior to Vascular Surgery

Peripheral Vascular Disease

Ireland, Netherlands
University of Limerick
UL Hospitals, Limerick

Terminated

Oral Nutritional Supplement in Reducing Surgical Site Infections

Peripheral Vascular Disease | Claudication

Ireland
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Completed

Treatment of High and Very High riSk Dyslipidemic pAtients for the PreveNTion of CardiOvasculaR Events (SANTORINI)

Cardiovascular Diseases | Dyslipidemia | Hypercholesterolemia | Atherosclerotic Cardiovascular Disease

Finland, Netherlands, Spain, Belgium, Sweden, Austria, United Kingdom, Switzerland, Denmark, France, Germany, Portugal, Italy, Ireland
Mid Western Regional Hospital, Ireland

Completed

Preconditioning Shields Against Vascular Events in Surgery (SAVES)

Carotid Atherosclerosis | Abdominal Aortic Aneurysm | Critical Lower Limb Ischaemia

Ireland
National University of Ireland, Galway, Ireland
University College Hospital Galway

Completed

Effects of Remote Ischemic Preconditioning on Moderate PVD Patients A Pilot Randomized Control Trial (RIPC-PVD)

Peripheral Arterial Diseases

Ireland
Esperion Therapeutics, Inc.

Completed

Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) in Patients With Hyperlipidemia and Statin Intolerant (CLEAR Serenity)

Hypercholesterolemia | Atherosclerotic Cardiovascular Disease | Statin Adverse Reaction

United States, Canada
Sanofi
Regeneron Pharmaceuticals

Completed

ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab

Atherosclerotic Cardiovascular Disease

China, Hong Kong, Austria, Bulgaria, Norway, Peru, France, Japan, Spain, Lithuania, Philippines, Israel, Belgium, Croatia, Poland, Hungary, Chile, Mexico, Latvia, Singapore, Switzerland, Colombia, Greece, Ukraine, Turkey, Finland, United States and more
Mid Western Regional Hospital, Ireland

Unknown

RCT to Evaluate the Renal Protective Effects of Remote Ischaemic Preconditioning in Peripheral Angioplasty

Peripheral Vascular Disease

Ireland
University College Dublin
Mater Misericordiae University Hospital

Not yet recruiting

COlchicine iN Circulating Inflammatory Markers After StrokE (CONCISE) (CONCISE)

Ischemic Stroke | Atherosclerosis

Ireland
National University of Ireland, Galway, Ireland
University Hospital of Limerick; University College Hospital Galway

Suspended

Effects of Remote Ischemic Preconditioning on Restenosis Post Lower Limb Revascularization Angioplasty

Peripheral Vascular Diseases

Ireland
University Hospital of Limerick

Completed

Cost Analysis of Vascular Surgical Techniques

Critical Limb Ischemia

Ireland
Amgen

Completed

Getting to an Improved Understanding of Low-Density Lipoprotein Cholesterol and Dyslipidemia Management (GOULD) a Registry of High Cardiovascular Risk Subjects in the United States

Dyslipidemia | Medical Conditions to be Studied | ASCVD Management

United States
Mid Western Regional Hospital, Ireland

Unknown

Preconditioning Shields Against Vascular Events in Surgery (SAVES-F)

Carotid Atherosclerosis | Abdominal Aortic Aneurysm | Critical Lower Limb Ischaemia

Ireland
Cordis Corporation

Completed

An Observational Registry Using Drug Eluting Stents (DES) in Patients in a Real-World Setting (DEScover Registry). (DESCOVER)

Cardiovascular Diseases | Arteriosclerosis | Atherosclerosis | Vascular Disease | Arterial Occlusive Disease

United States
University of Ulster
DSM Ltd; Public Health Agency (Northern Ireland)

Recruiting

Optimal Nutrition for Prevention of Hypertension in Pregnancy (OptiPREG)

Pregnancy | Blood Pressure

Ireland, United Kingdom
Boston Scientific Corporation

Completed

RANGER™ Paclitaxel Coated Balloon vs Standard Balloon Angioplasty (RANGER II SFA)

Atherosclerosis | Peripheral Artery Disease | Plaque, Atherosclerotic | Artery Diseases, Peripheral | Occlusive Arterial Disease

United States, Belgium, Canada, Japan, Austria, New Zealand
Providence VA Medical Center
Merck Sharp & Dohme LLC

Completed

Strategies to Maintain Cardiac Risk Control After Discharge From Cardiovascular Risk Reduction Clinic

Hypertension | Diabetes | Dyslipidemia | Coronary Atherosclerosis

United States
GlaxoSmithKline

Completed

An Imaging Study in Patients With Atherosclerosis Taking Rilapladib or Placebo for 12 Weeks

Atherosclerosis

United States
Novartis Pharmaceuticals

Recruiting

Coronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic Plaque Progression in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events (V-PLAQUE)

Coronary Artery Disease

United States, Italy, Spain, France, Korea, Republic of, Hungary, Japan, Argentina, China, India, Belgium, Switzerland, United Kingdom, Canada, Australia, Brazil, Chile, Ireland
KU Leuven
Dublin City University

Completed

Technology-enabled Cardiac Rehabilitation Through PATHway. Feasibility, Clinical Effectiveness and Cost-effectiveness (PATHway)

Cardiovascular Disease

Ireland, Belgium
Royal College of Surgeons, Ireland
Irish Heart Foundation

Completed

Enteric Coating as a Factor in Aspirin Resistance

Cardiovascular Disease

Ireland
University of Limerick

Completed

Antithrombotic Activities of a Novel Yoghurt Drink: a Postprandial Study

Cardiovascular Diseases

Ireland
National Institute on Aging (NIA)

Completed

Research on Aging Project in Iceland: Second Stage

Obesity | Atherosclerosis | Osteoporosis | Alzheimer's Disease | Glucose Abnormalities | Vascular Dimentia

Iceland
University of Limerick

Completed

Antithrombotic Activities of a Novel Yogurt Drink

Cardiovascular Diseases

Ireland
University College Hospital Galway
National University of Ireland, Galway, Ireland; European Research Council

Completed

Clarifying Optimal Sodium Intake Project (COSIP-1)

Hypertension | Cardiovascular Disease | Blood Pressure | Kidney Disease

Ireland
Celgene Corporation

Terminated

Prevention of Restenosis Following Revascularization

Vascular Disease, Peripheral

United States
University Hospital of Limerick

Recruiting

The Biomechanical Study of Diseased Human Carotid, Femoral and Abdominal Aortic Tissue

Vascular Diseases

Ireland
University Hospital of Limerick
University of Limerick

Terminated

The Role of Unsteady Wall Shears Stress Stimuli on Human Umbilical Vein Endothelial Cells Harvested From Umbilical Cords (HUVEC)

Vascular Diseases

Ireland
Queen's University, Belfast

Completed

A Study Examining Effects of Apples/ Apple Products on Heart Disease Risk (APPS)

Cardiovascular Disease

United Kingdom
Gardia Medical

Completed

Evaluation of WIRION™ EPS in Lower Extremities Arteries (WISE-LE)

Peripheral Arterial Disease (PAD)

United States, Germany
Mid Western Regional Hospital, Ireland

Completed

Efficacy of Patient Centred Information for Vascular Disease

Vascular Disease

Ireland
Vermillion, Inc.

Completed

Clinical Trial for Evaluation of Vermillion's Blood Test to Predict the Probability of Peripheral Artery Disease (PAD-001)

Peripheral Artery Disease

United States
Boston Scientific Corporation

Active, not recruiting

Trial Comparing ELUVIA Versus Bare Metal Stent in Treatment of Superficial Femoral and/or Proximal Popliteal Artery (EMINENT)

Vascular Diseases | Arteriosclerosis | Arterial Occlusive Diseases | Atherosclerosis

Germany, Ireland, Belgium, United Kingdom, France, Switzerland, Spain, Austria, Italy, Netherlands
Royal College of Surgeons, Ireland
Connolly Hospital Blanchardstown

Completed

Whole-task Hybrid Simulation Improves Medical Student Competence in Cardiology Clerkship

Valvular Heart Disease

Ireland
Children's Health Ireland at Crumlin
CHI Research & Innovation Office

Not yet recruiting

Impact of Exercise Training on Single Ventricle Function in Paediatric Fontan Patients

Univentricular Heart

Ireland
St. James's Hospital, Ireland

Unknown

Optimum Duration of Compression Stockings After Endovenous Varicose Vein Surgery

Varicose Veins

Ireland
Shockwave Medical, Inc.

Active, not recruiting

FORWARD PAD IDE Study With the Shockwave Mini S IVL Catheter (FORWARD PAD)

Peripheral Arterial Disease

United States
University of Limerick

Completed

In Vitro And Ex Vivo Anti-Inflammatory Activities Of Salmon Polar Lipids

Cardiovascular Diseases

Ireland

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