Hypofraktioneret strålebehandling efter mastektomi til forebyggelse af tilbagefald hos patienter med stadium IIa-IIIa brystkræft
5. februar 2026 opdateret af: Alliance for Clinical Trials in Oncology
RT CHARM: fase III randomiseret forsøg med hypofraktioneret postmastektomi stråling med brystrekonstruktion
Dette randomiserede fase III-forsøg undersøger, hvor godt hypofraktioneret strålebehandling virker til at forhindre tilbagefald hos patienter med stadium IIa-IIIa-kræft, som har gennemgået mastektomi.
Hypofraktioneret strålebehandling giver højere doser af strålebehandling over en kortere periode og kan dræbe flere tumorceller, der er tilbage efter operationen og have færre bivirkninger.
Studieoversigt
Status
Aktiv, ikke rekrutterende
Betingelser
Detaljeret beskrivelse
PRIMÆRE MÅL:
I. At evaluere om rekonstruktionskomplikationsraten 24 måneder efter stråling er ikke ringere end hypofraktionering.
SEKUNDÆRE MÅL:
I. At evaluere forekomsten af akutte og sene strålingskomplikationer baseret på Common Terminology Criteria for Adverse Events (CTCAE) 4.0 toksicitet.
II. At evaluere den lokale og lokale regionale gentagelsesrate. III. At sammenligne rekonstruktionskomplikationsrater baseret på rekonstruktionsmetode (autologt +/- implantat versus kun [vs] implantat) og timing for modtaget rekonstruktion (umiddelbar vs. hensigt med forsinket).
TERTIÆRE MÅL:
I. At evaluere rekonstruerede brystfotografiske kosmetiske resultater med hypofraktioneret stråling sammenlignet med standardfraktionering 24 måneder efter stråling.
II. At evaluere rekonstruerede brystfotografiske kosmetiske resultater 24 måneder efter stråling baseret på metoden og tidspunktet for rekonstruktion modtaget.
III. At estimere forekomsten af armlymfødem efter behandlingsarm. IV. At sammenligne fysisk velvære, psykosocialt velvære, seksuelt velvære, tilfredshed med bryst/brystvorter/mave og tilfredshed med det samlede resultat mellem behandlingsarmene 24 måneder efter stråling.
V. At estimere patienttilfredsheden med forsøgsdeltagelse efter behandlingsarm som målt med Was It Worth It-spørgeskemaet 24 måneder efter stråling.
VI. At sammenligne de direkte og indirekte patientomkostninger til strålebehandling efter behandlingsarm.
VII. At sammenligne patientrapporterede samlede sundhedsydelsesudnyttelse 12 måneder efter afslutningen af strålingen.
VIII. At sammenligne den økonomiske effekt af behandlingen. IX. At analysere polymorfier i MDM2 og i gener, herunder TP53, ATM, TGFB1, IL4, IL6 og IL10 og bestemme korrelationer med en højere sandsynlighed for uønskede strålingsreaktioner (strålingsfølsomhed) og med toksiciteter.
X. At analysere polymorfier i MDM2 og i gener, herunder TP53, ATM, TGFB1, IL4, IL6 og IL10 for at bestemme korrelationer med sekundære endepunkter såsom lokal-regional kontrol.
OVERSIGT: Patienterne er randomiseret til 1 ud af 2 grupper.
GRUPPE I: Patienter gennemgår daglig strålebehandling mandag-fredag i 5-6 uger.
GRUPPE II: Patienter gennemgår hypofraktioneret strålebehandling dagligt mandag-fredag i 3-4 uger.
Efter afslutning af undersøgelsen følges patienterne op i 5 år.
Undersøgelsestype
Interventionel
Tilmelding (Faktiske)
898
Fase
- Fase 3
Kontakter og lokationer
Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.
Studiesteder
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Alberta
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Calgary, Alberta, Canada, T2N 4N2
- Tom Baker Cancer Centre
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British Columbia
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Kelowna, British Columbia, Canada, V1Y 5L3
- BCCA-Cancer Centre for the Southern Interior
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Victoria, British Columbia, Canada, V8R 6V5
- BCCA-Vancouver Island Cancer Centre
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Ontario
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Barrie, Ontario, Canada, L4M 6M2
- Royal Victoria Regional Health Centre
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Hamilton, Ontario, Canada, L8V 5C2
- Juravinski Cancer Centre at Hamilton Health Sciences
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Newmarket, Ontario, Canada, L3Y 2P9
- Stronach Regional Health Centre at Southlake
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Toronto, Ontario, Canada, M5G 2M9
- University Health Network-Princess Margaret Hospital
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Toronto, Ontario, Canada, M4N 3M5
- Odette Cancer Centre- Sunnybrook Health Sciences Centre
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Quebec
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Gatineau, Quebec, Canada, J8P 7H2
- CISSS de l'Outaouais
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Montreal, Quebec, Canada, H3T 1E2
- Jewish General Hospital
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Montreal, Quebec, Canada, H2X 3E4
- CHUM - Centre Hospitalier de l'Universite de Montreal
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Montreal, Quebec, Canada, H1T 2M4
- CIUSSSEMTL-Hopital Maisonneuve-Rosemont
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Québec, Quebec, Canada, G1R 2J6
- CHU de Quebec-L'Hotel-Dieu de Quebec (HDQ)
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Alaska
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Anchorage, Alaska, Forenede Stater, 98508
- Anchorage Associates in Radiation Medicine
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Anchorage, Alaska, Forenede Stater, 99508
- Alaska Breast Care and Surgery LLC
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Anchorage, Alaska, Forenede Stater, 99508
- Alaska Oncology and Hematology LLC
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Anchorage, Alaska, Forenede Stater, 99508
- Alaska Women's Cancer Care
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Anchorage, Alaska, Forenede Stater, 99508
- Anchorage Oncology Centre
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Anchorage, Alaska, Forenede Stater, 99508
- Katmai Oncology Group
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Anchorage, Alaska, Forenede Stater, 99508
- Providence Alaska Medical Center
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Anchorage, Alaska, Forenede Stater, 99504
- Anchorage Radiation Therapy Center
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Fairbanks, Alaska, Forenede Stater, 99701
- Fairbanks Memorial Hospital
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Arizona
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Kingman, Arizona, Forenede Stater, 86401
- Kingman Regional Medical Center
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Phoenix, Arizona, Forenede Stater, 85004
- Cancer Center at Saint Joseph's
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Arkansas
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Fort Smith, Arkansas, Forenede Stater, 72903
- Mercy Hospital Fort Smith
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Hot Springs, Arkansas, Forenede Stater, 71913
- CHI Saint Vincent Cancer Center Hot Springs
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Little Rock, Arkansas, Forenede Stater, 72205
- University of Arkansas for Medical Sciences
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California
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Antioch, California, Forenede Stater, 94531
- Kaiser Permanente-Deer Valley Medical Center
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Arroyo Grande, California, Forenede Stater, 93420
- PCR Oncology
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Arroyo Grande, California, Forenede Stater, 93420
- Mission Hope Medical Oncology - Arroyo Grande
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Burbank, California, Forenede Stater, 91505
- Providence Saint Joseph Medical Center/Disney Family Cancer Center
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Corona, California, Forenede Stater, 92879
- City of Hope Corona
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Costa Mesa, California, Forenede Stater, 92627
- UC Irvine Health Cancer Center-Newport
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Duarte, California, Forenede Stater, 91010
- City of Hope Comprehensive Cancer Center
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Dublin, California, Forenede Stater, 94568
- Kaiser Permanente Dublin
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Dublin, California, Forenede Stater, 94568
- Epic Care-Dublin
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Emeryville, California, Forenede Stater, 94608
- Bay Area Breast Surgeons Inc
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Emeryville, California, Forenede Stater, 94608
- Epic Care Partners in Cancer Care
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Fremont, California, Forenede Stater, 94538
- Kaiser Permanente-Fremont
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Fresno, California, Forenede Stater, 93720
- Kaiser Permanente-Fresno
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Fresno, California, Forenede Stater, 93720
- Fresno Cancer Center
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Los Angeles, California, Forenede Stater, 90033
- USC / Norris Comprehensive Cancer Center
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Los Angeles, California, Forenede Stater, 90033
- Los Angeles County-USC Medical Center
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Los Angeles, California, Forenede Stater, 90048
- Cedars Sinai Medical Center
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Martinez, California, Forenede Stater, 94553-3156
- Contra Costa Regional Medical Center
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Modesto, California, Forenede Stater, 95356
- Kaiser Permanente-Modesto
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Newport Beach, California, Forenede Stater, 92663
- USC Norris Oncology/Hematology-Newport Beach
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Oakland, California, Forenede Stater, 94611
- Kaiser Permanente-Oakland
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Oakland, California, Forenede Stater, 94611
- Kaiser Permanente Oakland-Broadway
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Oakland, California, Forenede Stater, 94609
- Alta Bates Summit Medical Center - Summit Campus
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Oakland, California, Forenede Stater, 94609
- Bay Area Tumor Institute
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Orange, California, Forenede Stater, 92868
- UC Irvine Health/Chao Family Comprehensive Cancer Center
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Orange, California, Forenede Stater, 92868
- Saint Joseph Hospital - Orange
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Pasadena, California, Forenede Stater, 91105
- Keck Medical Center of USC Pasadena
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Rancho Cordova, California, Forenede Stater, 95670
- Kaiser Permanente-Rancho Cordova Cancer Center
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Redwood City, California, Forenede Stater, 94063
- Kaiser Permanente-Redwood City
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Redwood City, California, Forenede Stater, 94063
- Kaiser Permanente- Marshall Medical Offices
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Richmond, California, Forenede Stater, 94801
- Kaiser Permanente-Richmond
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Rohnert Park, California, Forenede Stater, 94928
- Rohnert Park Cancer Center
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Roseville, California, Forenede Stater, 95678
- The Permanente Medical Group-Roseville Radiation Oncology
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Roseville, California, Forenede Stater, 95661
- Kaiser Permanente-Roseville
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Sacramento, California, Forenede Stater, 95814
- Kaiser Permanente Downtown Commons
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Sacramento, California, Forenede Stater, 95823
- Kaiser Permanente-South Sacramento
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Sacramento, California, Forenede Stater, 95823
- South Sacramento Cancer Center
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Sacramento, California, Forenede Stater, 95825
- Kaiser Permanente - Sacramento
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San Francisco, California, Forenede Stater, 94115
- Kaiser Permanente-San Francisco
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San Jose, California, Forenede Stater, 95119
- Kaiser Permanente-Santa Teresa-San Jose
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San Leandro, California, Forenede Stater, 94577
- Kaiser Permanente San Leandro
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San Luis Obispo, California, Forenede Stater, 93401
- Pacific Central Coast Health Center-San Luis Obispo
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San Rafael, California, Forenede Stater, 94903
- Kaiser San Rafael-Gallinas
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San Rafael, California, Forenede Stater, 94903
- Kaiser Permanente-San Rafael
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Santa Clara, California, Forenede Stater, 95051
- Kaiser Permanente Medical Center - Santa Clara
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Santa Maria, California, Forenede Stater, 93444
- Mission Hope Medical Oncology - Santa Maria
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Santa Rosa, California, Forenede Stater, 95403
- Kaiser Permanente-Santa Rosa
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South Pasadena, California, Forenede Stater, 91030
- City of Hope South Pasadena
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South San Francisco, California, Forenede Stater, 94080
- Kaiser Permanente Cancer Treatment Center
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South San Francisco, California, Forenede Stater, 94080
- Kaiser Permanente-South San Francisco
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Stockton, California, Forenede Stater, 95210
- Kaiser Permanente-Stockton
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Torrance, California, Forenede Stater, 90509
- Torrance Memorial Medical Center
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Torrance, California, Forenede Stater, 90505
- Torrance Memorial Physician Network - Cancer Care
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Vacaville, California, Forenede Stater, 95688
- Kaiser Permanente Medical Center-Vacaville
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Vallejo, California, Forenede Stater, 94589
- Kaiser Permanente-Vallejo
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Walnut Creek, California, Forenede Stater, 94596
- Kaiser Permanente-Walnut Creek
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Walnut Creek, California, Forenede Stater, 94597
- Epic Care Cyberknife Center
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Colorado
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Aurora, Colorado, Forenede Stater, 80045
- University of Colorado Hospital
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Aurora, Colorado, Forenede Stater, 80012
- Rocky Mountain Cancer Centers-Aurora
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Aurora, Colorado, Forenede Stater, 80012
- The Medical Center of Aurora
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Boulder, Colorado, Forenede Stater, 80301
- Boulder Community Hospital
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Boulder, Colorado, Forenede Stater, 80303
- Boulder Community Foothills Hospital
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Boulder, Colorado, Forenede Stater, 80304
- Rocky Mountain Cancer Centers-Boulder
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Centennial, Colorado, Forenede Stater, 80112
- Rocky Mountain Cancer Centers - Centennial
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Colorado Springs, Colorado, Forenede Stater, 80907
- Penrose-Saint Francis Healthcare
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Colorado Springs, Colorado, Forenede Stater, 80909
- UCHealth Memorial Hospital Central
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Colorado Springs, Colorado, Forenede Stater, 80907
- Rocky Mountain Cancer Centers-Penrose
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Colorado Springs, Colorado, Forenede Stater, 80920
- Memorial Hospital North
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Denver, Colorado, Forenede Stater, 80210
- Porter Adventist Hospital
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Denver, Colorado, Forenede Stater, 80218
- Presbyterian - Saint Lukes Medical Center - Health One
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Denver, Colorado, Forenede Stater, 80218
- SCL Health Saint Joseph Hospital
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Denver, Colorado, Forenede Stater, 80220
- Rose Medical Center
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Denver, Colorado, Forenede Stater, 80218
- Rocky Mountain Cancer Centers-Midtown
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Denver, Colorado, Forenede Stater, 80220
- Rocky Mountain Cancer Centers-Rose
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Denver, Colorado, Forenede Stater, 80204
- Denver Health Medical Center
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Denver, Colorado, Forenede Stater, 80218
- Colorado Blood Cancer Institute
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Denver, Colorado, Forenede Stater, 80204
- Cancer Center of Colorado at Sloan's Lake
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Denver, Colorado, Forenede Stater, 80209
- The Women's Imaging Center
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Denver, Colorado, Forenede Stater, 80206
- National Jewish Health-Main Campus
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Denver, Colorado, Forenede Stater, 80220
- Western Surgical Care
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Durango, Colorado, Forenede Stater, 81301
- Mercy Medical Center
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Durango, Colorado, Forenede Stater, 81301
- Southwest Oncology PC
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Englewood, Colorado, Forenede Stater, 80113
- Mountain Blue Cancer Care Center - Swedish
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Englewood, Colorado, Forenede Stater, 80113
- Swedish Medical Center
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Englewood, Colorado, Forenede Stater, 80113
- Rocky Mountain Cancer Centers - Swedish
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Englewood, Colorado, Forenede Stater, 80113
- The Melanoma and Skin Cancer Institute
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Glenwood Springs, Colorado, Forenede Stater, 81601
- Valley View Hospital Cancer Center
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Golden, Colorado, Forenede Stater, 80401
- Mountain Blue Cancer Care Center
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Golden, Colorado, Forenede Stater, 80401
- National Jewish Health-Western Hematology Oncology
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Grand Junction, Colorado, Forenede Stater, 81501
- Saint Mary's Hospital and Regional Medical Center
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Grand Junction, Colorado, Forenede Stater, 81505
- Grand Valley Oncology
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Greeley, Colorado, Forenede Stater, 80631
- North Colorado Medical Center
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Lafayette, Colorado, Forenede Stater, 80026
- Good Samaritan Medical Center
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Lakewood, Colorado, Forenede Stater, 80228
- Saint Anthony Hospital
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Lakewood, Colorado, Forenede Stater, 80228
- Rocky Mountain Cancer Centers-Lakewood
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Littleton, Colorado, Forenede Stater, 80120
- Rocky Mountain Cancer Centers-Littleton
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Littleton, Colorado, Forenede Stater, 80122
- Littleton Adventist Hospital
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Lone Tree, Colorado, Forenede Stater, 80124
- Sky Ridge Medical Center
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Lone Tree, Colorado, Forenede Stater, 80124
- Rocky Mountain Cancer Centers-Sky Ridge
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Longmont, Colorado, Forenede Stater, 80501
- Longmont United Hospital
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Longmont, Colorado, Forenede Stater, 80501
- Rocky Mountain Cancer Centers-Longmont
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Loveland, Colorado, Forenede Stater, 80539
- McKee Medical Center
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Parker, Colorado, Forenede Stater, 80138
- Parker Adventist Hospital
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Parker, Colorado, Forenede Stater, 80138
- Rocky Mountain Cancer Centers-Parker
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Pueblo, Colorado, Forenede Stater, 81004
- Saint Mary Corwin Medical Center
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Pueblo, Colorado, Forenede Stater, 81008
- Rocky Mountain Cancer Centers - Pueblo
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Thornton, Colorado, Forenede Stater, 80260
- Rocky Mountain Cancer Centers-Thornton
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Thornton, Colorado, Forenede Stater, 80260
- National Jewish Health-Northern Hematology Oncology
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Wheat Ridge, Colorado, Forenede Stater, 80033
- SCL Health Lutheran Medical Center
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Connecticut
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Middletown, Connecticut, Forenede Stater, 06457
- Middlesex Hospital
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Delaware
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Frankford, Delaware, Forenede Stater, 19945
- Beebe South Coastal Health Campus
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Lewes, Delaware, Forenede Stater, 19958
- Beebe Medical Center
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Newark, Delaware, Forenede Stater, 19713
- Helen F Graham Cancer Center
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Newark, Delaware, Forenede Stater, 19713
- Delaware Clinical and Laboratory Physicians PA
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Newark, Delaware, Forenede Stater, 19713
- Medical Oncology Hematology Consultants PA
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Newark, Delaware, Forenede Stater, 19718
- Christiana Care Health System-Christiana Hospital
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Rehoboth Beach, Delaware, Forenede Stater, 19971
- Beebe Health Campus
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Seaford, Delaware, Forenede Stater, 19973
- TidalHealth Nanticoke / Allen Cancer Center
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Wilmington, Delaware, Forenede Stater, 19801
- Christiana Care Health System-Wilmington Hospital
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District of Columbia
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Washington D.C., District of Columbia, Forenede Stater, 20037
- George Washington University Medical Center
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Florida
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Altamonte Springs, Florida, Forenede Stater, 32701
- AdventHealth Altamonte
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Atlantis, Florida, Forenede Stater, 33462
- John Fitzgerald Kennedy Medical Center
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Boca Raton, Florida, Forenede Stater, 33486
- Boca Raton Regional Hospital
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Celebration, Florida, Forenede Stater, 34747
- AdventHealth Celebration
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Coral Gables, Florida, Forenede Stater, 33146
- UM Sylvester Comprehensive Cancer Center at Coral Gables
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Deerfield Beach, Florida, Forenede Stater, 33442
- UM Sylvester Comprehensive Cancer Center at Deerfield Beach
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Gainesville, Florida, Forenede Stater, 32610
- University of Florida Health Science Center - Gainesville
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Hollywood, Florida, Forenede Stater, 33021
- Memorial Regional Hospital/Joe DiMaggio Children's Hospital
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Jacksonville, Florida, Forenede Stater, 32224-9980
- Mayo Clinic in Florida
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Kissimmee, Florida, Forenede Stater, 34744
- AdventHealth Kissimmee
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Miami, Florida, Forenede Stater, 33136
- University of Miami Miller School of Medicine-Sylvester Cancer Center
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Orlando, Florida, Forenede Stater, 32803
- AdventHealth Orlando
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Orlando, Florida, Forenede Stater, 32803
- AdventHealth Medical Group Urology at Orlando
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Orlando, Florida, Forenede Stater, 32822
- AdventHealth East Orlando
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Pembroke Pines, Florida, Forenede Stater, 33028
- Memorial Hospital West
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Tampa, Florida, Forenede Stater, 33612
- Moffitt Cancer Center
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Tampa, Florida, Forenede Stater, 33607
- Moffitt Cancer Center-International Plaza
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Tampa, Florida, Forenede Stater, 33612
- Moffitt Cancer Center - McKinley Campus
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Winter Park, Florida, Forenede Stater, 32792
- AdventHealth Winter Park
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Georgia
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Alpharetta, Georgia, Forenede Stater, 30005
- Northside Hospital-Alpharetta
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Atlanta, Georgia, Forenede Stater, 30308
- Emory University Hospital Midtown
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Atlanta, Georgia, Forenede Stater, 30322
- Emory University Hospital/Winship Cancer Institute
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Atlanta, Georgia, Forenede Stater, 30342
- Emory Saint Joseph's Hospital
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Atlanta, Georgia, Forenede Stater, 30303
- Grady Health System
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Atlanta, Georgia, Forenede Stater, 30309
- Piedmont Hospital
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Atlanta, Georgia, Forenede Stater, 30342
- Northside Hospital
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Canton, Georgia, Forenede Stater, 30115
- Northside Hospital-Cherokee
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Cumming, Georgia, Forenede Stater, 30041
- Northside Hospital-Forsyth
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Fayetteville, Georgia, Forenede Stater, 30214
- Piedmont Fayette Hospital
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Newnan, Georgia, Forenede Stater, 30265
- Piedmont Newnan Hospital
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Savannah, Georgia, Forenede Stater, 31405
- Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
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Savannah, Georgia, Forenede Stater, 31405
- Low Country Cancer Care Associates PC
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Savannah, Georgia, Forenede Stater, 31405
- Summit Cancer Care-Candler
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Stockbridge, Georgia, Forenede Stater, 30281
- Piedmont Henry Hospital
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Hawaii
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Honolulu, Hawaii, Forenede Stater, 96819
- Kaiser Permanente Moanalua Medical Center
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Idaho
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Boise, Idaho, Forenede Stater, 83706
- Saint Alphonsus Cancer Care Center-Boise
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Boise, Idaho, Forenede Stater, 83712
- Saint Luke's Cancer Institute - Boise
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Caldwell, Idaho, Forenede Stater, 83605
- Saint Alphonsus Cancer Care Center-Caldwell
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Coeur d'Alene, Idaho, Forenede Stater, 83814
- Kootenai Health - Coeur d'Alene
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Emmett, Idaho, Forenede Stater, 83617
- Walter Knox Memorial Hospital
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Fruitland, Idaho, Forenede Stater, 83619
- Saint Luke's Cancer Institute - Fruitland
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Meridian, Idaho, Forenede Stater, 83642
- Idaho Urologic Institute-Meridian
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Meridian, Idaho, Forenede Stater, 83642
- Saint Luke's Cancer Institute - Meridian
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Nampa, Idaho, Forenede Stater, 83686
- Saint Alphonsus Medical Center-Nampa
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Nampa, Idaho, Forenede Stater, 83686
- Saint Luke's Cancer Institute - Nampa
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Post Falls, Idaho, Forenede Stater, 83854
- Kootenai Clinic Cancer Services - Post Falls
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Sandpoint, Idaho, Forenede Stater, 83864
- Kootenai Cancer Clinic
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Twin Falls, Idaho, Forenede Stater, 83301
- Saint Luke's Cancer Institute - Twin Falls
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Illinois
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Alton, Illinois, Forenede Stater, 62002
- Saint Anthony's Health
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Aurora, Illinois, Forenede Stater, 60504
- Rush - Copley Medical Center
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Bloomington, Illinois, Forenede Stater, 61704
- Illinois CancerCare-Bloomington
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Burr Ridge, Illinois, Forenede Stater, 60527
- Loyola Center for Health at Burr Ridge
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Canton, Illinois, Forenede Stater, 61520
- Illinois CancerCare-Canton
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Carbondale, Illinois, Forenede Stater, 62902
- Memorial Hospital of Carbondale
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Carterville, Illinois, Forenede Stater, 62918
- SIH Cancer Institute
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Carthage, Illinois, Forenede Stater, 62321
- Illinois CancerCare-Carthage
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Centralia, Illinois, Forenede Stater, 62801
- Centralia Oncology Clinic
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Chicago, Illinois, Forenede Stater, 60611
- Northwestern University
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Chicago, Illinois, Forenede Stater, 60612
- Rush University Medical Center
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Chicago, Illinois, Forenede Stater, 60637
- University of Chicago Comprehensive Cancer Center
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Chicago, Illinois, Forenede Stater, 60612
- University of Illinois
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Danville, Illinois, Forenede Stater, 61832
- Carle on Vermilion
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DeKalb, Illinois, Forenede Stater, 60115
- Northwestern Medicine Cancer Center Kishwaukee
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Decatur, Illinois, Forenede Stater, 62526
- Decatur Memorial Hospital
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Decatur, Illinois, Forenede Stater, 62526
- Cancer Care Specialists of Illinois - Decatur
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Dixon, Illinois, Forenede Stater, 61021
- Illinois CancerCare-Dixon
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Effingham, Illinois, Forenede Stater, 62401
- Crossroads Cancer Center
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Effingham, Illinois, Forenede Stater, 62401
- Carle Physician Group-Effingham
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Eureka, Illinois, Forenede Stater, 61530
- Illinois CancerCare-Eureka
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Galesburg, Illinois, Forenede Stater, 61401
- Western Illinois Cancer Treatment Center
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Galesburg, Illinois, Forenede Stater, 61401
- Illinois CancerCare-Galesburg
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Geneva, Illinois, Forenede Stater, 60134
- Northwestern Medicine Cancer Center Delnor
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Hinsdale, Illinois, Forenede Stater, 60521
- AMITA Health Cancer Institute and Outpatient Center
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Homer Glen, Illinois, Forenede Stater, 60491
- Loyola Medicine Homer Glen
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Kewanee, Illinois, Forenede Stater, 61443
- Illinois CancerCare-Kewanee Clinic
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Lake Forest, Illinois, Forenede Stater, 60045
- Northwestern Medicine Lake Forest Hospital
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Libertyville, Illinois, Forenede Stater, 60048
- Condell Memorial Hospital
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Macomb, Illinois, Forenede Stater, 61455
- Illinois CancerCare-Macomb
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Mattoon, Illinois, Forenede Stater, 61938
- Carle Physician Group-Mattoon/Charleston
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Maywood, Illinois, Forenede Stater, 60153
- Loyola University Medical Center
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Melrose Park, Illinois, Forenede Stater, 60160
- Marjorie Weinberg Cancer Center at Loyola-Gottlieb
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Moline, Illinois, Forenede Stater, 61265
- Trinity Medical Center
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Mount Vernon, Illinois, Forenede Stater, 62864
- Good Samaritan Regional Health Center
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New Lenox, Illinois, Forenede Stater, 60451
- UC Comprehensive Cancer Center at Silver Cross
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O'Fallon, Illinois, Forenede Stater, 62269
- Cancer Care Center of O'Fallon
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Orland Park, Illinois, Forenede Stater, 60462
- University of Chicago Medicine-Orland Park
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Ottawa, Illinois, Forenede Stater, 61350
- Illinois CancerCare-Ottawa Clinic
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Pekin, Illinois, Forenede Stater, 61554
- Illinois CancerCare-Pekin
-
Pekin, Illinois, Forenede Stater, 61554
- OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center
-
Peoria, Illinois, Forenede Stater, 61636
- Methodist Medical Center of Illinois
-
Peoria, Illinois, Forenede Stater, 61637
- OSF Saint Francis Medical Center
-
Peoria, Illinois, Forenede Stater, 61615
- Illinois CancerCare-Peoria
-
Peoria, Illinois, Forenede Stater, 61615
- OSF Saint Francis Radiation Oncology at Peoria Cancer Center
-
Peru, Illinois, Forenede Stater, 61354
- Illinois CancerCare-Peru
-
Peru, Illinois, Forenede Stater, 61354
- Valley Radiation Oncology
-
Princeton, Illinois, Forenede Stater, 61356
- Illinois CancerCare-Princeton
-
Rockford, Illinois, Forenede Stater, 61114
- SwedishAmerican Regional Cancer Center/ACT
-
Springfield, Illinois, Forenede Stater, 62781
- Memorial Medical Center
-
Springfield, Illinois, Forenede Stater, 62702
- Southern Illinois University School of Medicine
-
Springfield, Illinois, Forenede Stater, 62702
- Springfield Clinic
-
Swansea, Illinois, Forenede Stater, 62226
- Southwest Illinois Health Services LLP
-
Urbana, Illinois, Forenede Stater, 61801
- Carle Cancer Center
-
Urbana, Illinois, Forenede Stater, 61801
- The Carle Foundation Hospital
-
Warrenville, Illinois, Forenede Stater, 60555
- Northwestern Medicine Cancer Center Warrenville
-
Washington, Illinois, Forenede Stater, 61571
- Illinois CancerCare - Washington
-
Yorkville, Illinois, Forenede Stater, 60560
- Rush-Copley Healthcare Center
-
-
Iowa
-
Ames, Iowa, Forenede Stater, 50010
- McFarland Clinic PC - Ames
-
Ames, Iowa, Forenede Stater, 50010
- Mary Greeley Medical Center
-
Boone, Iowa, Forenede Stater, 50036
- McFarland Clinic PC-Boone
-
Carroll, Iowa, Forenede Stater, 51401
- Saint Anthony Regional Hospital
-
Clive, Iowa, Forenede Stater, 50325
- Mercy Cancer Center-West Lakes
-
Clive, Iowa, Forenede Stater, 50325
- Medical Oncology and Hematology Associates-West Des Moines
-
Council Bluffs, Iowa, Forenede Stater, 51503
- Alegent Health Mercy Hospital
-
Council Bluffs, Iowa, Forenede Stater, 51502
- Jennie Edmundson Memorial Hospital
-
Creston, Iowa, Forenede Stater, 50801
- Greater Regional Medical Center
-
Des Moines, Iowa, Forenede Stater, 50309
- Iowa Methodist Medical Center
-
Des Moines, Iowa, Forenede Stater, 50314
- Mercy Medical Center - Des Moines
-
Des Moines, Iowa, Forenede Stater, 50309
- Medical Oncology and Hematology Associates-Des Moines
-
Des Moines, Iowa, Forenede Stater, 50314
- Broadlawns Medical Center
-
Des Moines, Iowa, Forenede Stater, 50316
- Iowa Lutheran Hospital
-
Des Moines, Iowa, Forenede Stater, 50314
- Medical Oncology and Hematology Associates-Laurel
-
Fort Dodge, Iowa, Forenede Stater, 50501
- McFarland Clinic PC-Trinity Cancer Center
-
Fort Dodge, Iowa, Forenede Stater, 50501
- Trinity Regional Medical Center
-
Jefferson, Iowa, Forenede Stater, 50129
- McFarland Clinic PC-Jefferson
-
Marshalltown, Iowa, Forenede Stater, 50158
- McFarland Clinic PC-Marshalltown
-
West Des Moines, Iowa, Forenede Stater, 50266-7700
- Methodist West Hospital
-
West Des Moines, Iowa, Forenede Stater, 50266
- Mercy Medical Center-West Lakes
-
-
Kansas
-
Coffeyville, Kansas, Forenede Stater, 67337
- Coffeyville Regional Medical Center
-
Garden City, Kansas, Forenede Stater, 67846
- Central Care Cancer Center - Garden City
-
Great Bend, Kansas, Forenede Stater, 67530
- Central Care Cancer Center - Great Bend
-
Hays, Kansas, Forenede Stater, 67601
- HaysMed University of Kansas Health System
-
Kansas City, Kansas, Forenede Stater, 66160
- University of Kansas Cancer Center
-
Kansas City, Kansas, Forenede Stater, 66112
- University of Kansas Cancer Center-West
-
Lawrence, Kansas, Forenede Stater, 66044
- Lawrence Memorial Hospital
-
Olathe, Kansas, Forenede Stater, 66061
- Olathe Health Cancer Center
-
Overland Park, Kansas, Forenede Stater, 66210
- University of Kansas Cancer Center-Overland Park
-
Overland Park, Kansas, Forenede Stater, 66211
- University of Kansas Hospital-Indian Creek Campus
-
Pittsburg, Kansas, Forenede Stater, 66762
- Ascension Via Christi - Pittsburg
-
Salina, Kansas, Forenede Stater, 67401
- Salina Regional Health Center
-
Topeka, Kansas, Forenede Stater, 66606
- University of Kansas Health System Saint Francis Campus
-
Westwood, Kansas, Forenede Stater, 66205
- University of Kansas Hospital-Westwood Cancer Center
-
Wichita, Kansas, Forenede Stater, 67214
- Ascension Via Christi Hospitals Wichita
-
-
Kentucky
-
Bardstown, Kentucky, Forenede Stater, 40004
- Flaget Memorial Hospital
-
Corbin, Kentucky, Forenede Stater, 40701
- Commonwealth Cancer Center-Corbin
-
Edgewood, Kentucky, Forenede Stater, 41017
- Saint Elizabeth Medical Center South
-
Fort Thomas, Kentucky, Forenede Stater, 41075
- Saint Elizabeth Fort Thomas
-
Lexington, Kentucky, Forenede Stater, 40504
- Saint Joseph Radiation Oncology Resource Center
-
Lexington, Kentucky, Forenede Stater, 40509
- Saint Joseph Hospital East
-
London, Kentucky, Forenede Stater, 40741
- Saint Joseph London
-
Louisville, Kentucky, Forenede Stater, 40202
- The James Graham Brown Cancer Center at University of Louisville
-
Louisville, Kentucky, Forenede Stater, 40202
- Jewish Hospital
-
Louisville, Kentucky, Forenede Stater, 40215
- Saints Mary and Elizabeth Hospital
-
Louisville, Kentucky, Forenede Stater, 40245
- Jewish Hospital Medical Center Northeast
-
Shepherdsville, Kentucky, Forenede Stater, 40165
- Jewish Hospital Medical Center South
-
-
Louisiana
-
Baton Rouge, Louisiana, Forenede Stater, 70809
- Mary Bird Perkins Cancer Center
-
Baton Rouge, Louisiana, Forenede Stater, 70817
- Woman's Hospital
-
Baton Rouge, Louisiana, Forenede Stater, 70817
- Our Lady of the Lake Medical Oncology
-
Baton Rouge, Louisiana, Forenede Stater, 70817
- Louisiana Hematology Oncology Associates
-
Covington, Louisiana, Forenede Stater, 70433
- Mary Bird Perkins Cancer Center - Covington
-
Houma, Louisiana, Forenede Stater, 70360
- Mary Bird Perkins Cancer Center - Houma
-
New Orleans, Louisiana, Forenede Stater, 70121
- Ochsner Medical Center Jefferson
-
New Orleans, Louisiana, Forenede Stater, 70112
- University Medical Center New Orleans
-
New Orleans, Louisiana, Forenede Stater, 70112
- Louisiana State University Health Science Center
-
-
Maryland
-
Annapolis, Maryland, Forenede Stater, 21401
- Anne Arundel Medical Center
-
Baltimore, Maryland, Forenede Stater, 21204
- Greater Baltimore Medical Center
-
Baltimore, Maryland, Forenede Stater, 21201
- University of Maryland/Greenebaum Cancer Center
-
Baltimore, Maryland, Forenede Stater, 21229
- Saint Agnes Hospital
-
Bel Air, Maryland, Forenede Stater, 21014
- UM Upper Chesapeake Medical Center
-
Bethesda, Maryland, Forenede Stater, 20889-5600
- Walter Reed National Military Medical Center
-
Columbia, Maryland, Forenede Stater, 21044
- Central Maryland Radiation Oncology in Howard County
-
Easton, Maryland, Forenede Stater, 21601
- University of Maryland Shore Medical Center at Easton
-
Glen Burnie, Maryland, Forenede Stater, 21061
- UM Baltimore Washington Medical Center/Tate Cancer Center
-
Ocean Pines, Maryland, Forenede Stater, 21811
- TidalHealth Richard A Henson Cancer Institute
-
Salisbury, Maryland, Forenede Stater, 21801
- TidalHealth Peninsula Regional
-
Silver Spring, Maryland, Forenede Stater, 20910
- Holy Cross Hospital
-
Towson, Maryland, Forenede Stater, 21204
- UM Saint Joseph Medical Center
-
-
Michigan
-
Battle Creek, Michigan, Forenede Stater, 49017
- Bronson Battle Creek
-
Bay City, Michigan, Forenede Stater, 48706
- McLaren Cancer Institute-Bay City
-
Brownstown, Michigan, Forenede Stater, 48183
- Henry Ford Cancer Institute-Downriver
-
Clarkston, Michigan, Forenede Stater, 48346
- McLaren Cancer Institute-Clarkston
-
Clinton Township, Michigan, Forenede Stater, 48038
- Henry Ford Macomb Hospital-Clinton Township
-
Dearborn, Michigan, Forenede Stater, 48124
- Beaumont Hospital - Dearborn
-
Detroit, Michigan, Forenede Stater, 48202
- Henry Ford Hospital
-
Escanaba, Michigan, Forenede Stater, 49829
- Green Bay Oncology - Escanaba
-
Farmington Hills, Michigan, Forenede Stater, 48336
- Beaumont Hospital - Farmington Hills
-
Flint, Michigan, Forenede Stater, 48532
- McLaren Cancer Institute-Flint
-
Grand Rapids, Michigan, Forenede Stater, 49503
- Spectrum Health at Butterworth Campus
-
Grand Rapids, Michigan, Forenede Stater, 49503
- Helen DeVos Children's Hospital at Spectrum Health
-
Grand Rapids, Michigan, Forenede Stater, 49503
- Mercy Health Saint Mary's
-
Grosse Pointe, Michigan, Forenede Stater, 48230
- William Beaumont Hospital-Grosse Pointe
-
Kalamazoo, Michigan, Forenede Stater, 49007
- West Michigan Cancer Center
-
Kalamazoo, Michigan, Forenede Stater, 49007
- Bronson Methodist Hospital
-
Kalamazoo, Michigan, Forenede Stater, 49048
- Borgess Medical Center
-
Lansing, Michigan, Forenede Stater, 48910
- McLaren-Greater Lansing
-
Lapeer, Michigan, Forenede Stater, 48446
- McLaren Cancer Institute-Lapeer Region
-
Mount Clemens, Michigan, Forenede Stater, 48043
- McLaren Cancer Institute-Macomb
-
Mount Pleasant, Michigan, Forenede Stater, 48858
- McLaren Cancer Institute-Central Michigan
-
Muskegon, Michigan, Forenede Stater, 49444
- Mercy Health Mercy Campus
-
Niles, Michigan, Forenede Stater, 49120
- Lakeland Hospital Niles
-
Norton Shores, Michigan, Forenede Stater, 49444
- Cancer and Hematology Centers of Western Michigan - Norton Shores
-
Owosso, Michigan, Forenede Stater, 48867
- McLaren Cancer Institute-Owosso
-
Petoskey, Michigan, Forenede Stater, 49770
- McLaren Cancer Institute-Northern Michigan
-
Port Huron, Michigan, Forenede Stater, 48060
- McLaren-Port Huron
-
Port Huron, Michigan, Forenede Stater, 48060
- Huron Medical Center PC
-
Reed City, Michigan, Forenede Stater, 49677
- Spectrum Health Reed City Hospital
-
Roseville, Michigan, Forenede Stater, 48066
- Michigan Cancer Specialists
-
Royal Oak, Michigan, Forenede Stater, 48073
- William Beaumont Hospital-Royal Oak
-
Royal Oak, Michigan, Forenede Stater, 48073
- Cancer Care Associates PC
-
Royal Oak, Michigan, Forenede Stater, 48073
- Comprehensive Medical Center PLLC
-
Royal Oak, Michigan, Forenede Stater, 48073
- Hematology Oncology Consultants PC
-
Royal Oak, Michigan, Forenede Stater, 48073
- Oakland Medical Group
-
Royal Oak, Michigan, Forenede Stater, 48067
- Oakland Colon Rectal Associates
-
Saint Joseph, Michigan, Forenede Stater, 49085
- Lakeland Medical Center Saint Joseph
-
Saint Joseph, Michigan, Forenede Stater, 49085
- Marie Yeager Cancer Center
-
Sterling Heights, Michigan, Forenede Stater, 48312
- Premier Hematology Oncology Care
-
Sterling Heights, Michigan, Forenede Stater, 48314
- Mitchell Folbe MD PC
-
Traverse City, Michigan, Forenede Stater, 49684
- Munson Medical Center
-
Troy, Michigan, Forenede Stater, 48085
- William Beaumont Hospital - Troy
-
Troy, Michigan, Forenede Stater, 48084
- Michigan Institute of Urology-Town Center
-
Troy, Michigan, Forenede Stater, 48085
- Claudia BR Herke MD PC
-
Troy, Michigan, Forenede Stater, 48098
- Hematology Oncology Consultants PC-Troy
-
West Bloomfield, Michigan, Forenede Stater, 48322
- Henry Ford West Bloomfield Hospital
-
Wyandotte, Michigan, Forenede Stater, 48192
- Henry Ford Wyandotte Hospital
-
Wyoming, Michigan, Forenede Stater, 49519
- Metro Health Hospital
-
-
Minnesota
-
Aitkin, Minnesota, Forenede Stater, 56431
- Riverwood Healthcare Center
-
Albert Lea, Minnesota, Forenede Stater, 56007
- Mayo Clinic Health System in Albert Lea
-
Bemidji, Minnesota, Forenede Stater, 56601
- Sanford Joe Lueken Cancer Center
-
Brainerd, Minnesota, Forenede Stater, 56401
- Essentia Health Saint Joseph's Medical Center
-
Burnsville, Minnesota, Forenede Stater, 55337
- Fairview Ridges Hospital
-
Burnsville, Minnesota, Forenede Stater, 55337
- Minnesota Oncology - Burnsville
-
Cambridge, Minnesota, Forenede Stater, 55008
- Cambridge Medical Center
-
Coon Rapids, Minnesota, Forenede Stater, 55433
- Mercy Hospital
-
Deer River, Minnesota, Forenede Stater, 56636
- Essentia Health - Deer River Clinic
-
Detroit Lakes, Minnesota, Forenede Stater, 56501
- Essentia Health Saint Mary's - Detroit Lakes Clinic
-
Duluth, Minnesota, Forenede Stater, 55805
- Essentia Health Cancer Center
-
Duluth, Minnesota, Forenede Stater, 55805
- Essentia Health Saint Mary's Medical Center
-
Duluth, Minnesota, Forenede Stater, 55805
- Miller-Dwan Hospital
-
Edina, Minnesota, Forenede Stater, 55435
- Fairview Southdale Hospital
-
Fergus Falls, Minnesota, Forenede Stater, 56537
- Lake Region Healthcare Corporation-Cancer Care
-
Fosston, Minnesota, Forenede Stater, 56542
- Essentia Health - Fosston
-
Fridley, Minnesota, Forenede Stater, 55432
- Unity Hospital
-
Hibbing, Minnesota, Forenede Stater, 55746
- Essentia Health Hibbing Clinic
-
Mankato, Minnesota, Forenede Stater, 56001
- Mayo Clinic Health Systems-Mankato
-
Maple Grove, Minnesota, Forenede Stater, 55369
- Fairview Clinics and Surgery Center Maple Grove
-
Maplewood, Minnesota, Forenede Stater, 55109
- Saint John's Hospital - Healtheast
-
Maplewood, Minnesota, Forenede Stater, 55109
- Minnesota Oncology Hematology PA-Maplewood
-
Minneapolis, Minnesota, Forenede Stater, 55415
- Hennepin County Medical Center
-
Minneapolis, Minnesota, Forenede Stater, 55407
- Abbott-Northwestern Hospital
-
Minneapolis, Minnesota, Forenede Stater, 55454
- Health Partners Inc
-
Monticello, Minnesota, Forenede Stater, 55362
- Monticello Cancer Center
-
New Ulm, Minnesota, Forenede Stater, 56073
- New Ulm Medical Center
-
Northfield, Minnesota, Forenede Stater, 55057
- Mayo Clinic Radiation Therapy-Northfield
-
Park Rapids, Minnesota, Forenede Stater, 56470
- Essentia Health - Park Rapids
-
Princeton, Minnesota, Forenede Stater, 55371
- Fairview Northland Medical Center
-
Robbinsdale, Minnesota, Forenede Stater, 55422
- North Memorial Medical Health Center
-
Rochester, Minnesota, Forenede Stater, 55905
- Mayo Clinic in Rochester
-
Saint Louis Park, Minnesota, Forenede Stater, 55416
- Park Nicollet Clinic - Saint Louis Park
-
Saint Paul, Minnesota, Forenede Stater, 55101
- Regions Hospital
-
Saint Paul, Minnesota, Forenede Stater, 55102
- United Hospital
-
Sandstone, Minnesota, Forenede Stater, 55072
- Essentia Health Sandstone
-
Shakopee, Minnesota, Forenede Stater, 55379
- Saint Francis Regional Medical Center
-
Stillwater, Minnesota, Forenede Stater, 55082
- Lakeview Hospital
-
Thief River Falls, Minnesota, Forenede Stater, 56701
- Sanford Thief River Falls Medical Center
-
Virginia, Minnesota, Forenede Stater, 55792
- Essentia Health Virginia Clinic
-
Waconia, Minnesota, Forenede Stater, 55387
- Ridgeview Medical Center
-
Willmar, Minnesota, Forenede Stater, 56201
- Rice Memorial Hospital
-
Woodbury, Minnesota, Forenede Stater, 55125
- Minnesota Oncology Hematology PA-Woodbury
-
Worthington, Minnesota, Forenede Stater, 56187
- Sanford Cancer Center Worthington
-
Wyoming, Minnesota, Forenede Stater, 55092
- Fairview Lakes Medical Center
-
-
Mississippi
-
Corinth, Mississippi, Forenede Stater, 38834
- The West Clinic - Corinth
-
Oxford, Mississippi, Forenede Stater, 38655
- Baptist Memorial Hospital and Cancer Center-Oxford
-
Southaven, Mississippi, Forenede Stater, 38671
- The West Clinic - Southaven
-
-
Missouri
-
Ballwin, Missouri, Forenede Stater, 63011
- Saint Louis Cancer and Breast Institute-Ballwin
-
Bolivar, Missouri, Forenede Stater, 65613
- Central Care Cancer Center - Bolivar
-
Bonne Terre, Missouri, Forenede Stater, 63628
- Parkland Health Center-Bonne Terre
-
Branson, Missouri, Forenede Stater, 65616
- Cox Cancer Center Branson
-
Cape Girardeau, Missouri, Forenede Stater, 63703
- Saint Francis Medical Center
-
Cape Girardeau, Missouri, Forenede Stater, 63703
- Southeast Cancer Center
-
City of Saint Peters, Missouri, Forenede Stater, 63376
- Siteman Cancer Center at Saint Peters Hospital
-
Columbia, Missouri, Forenede Stater, 65212
- University of Missouri - Ellis Fischel
-
Creve Coeur, Missouri, Forenede Stater, 63141
- Siteman Cancer Center at West County Hospital
-
Farmington, Missouri, Forenede Stater, 63640
- Parkland Health Center - Farmington
-
Jefferson City, Missouri, Forenede Stater, 65109
- Capital Region Southwest Campus
-
Joplin, Missouri, Forenede Stater, 64804
- Freeman Health System
-
Joplin, Missouri, Forenede Stater, 64804
- Mercy Hospital Joplin
-
Kansas City, Missouri, Forenede Stater, 64154
- University of Kansas Cancer Center - North
-
Kansas City, Missouri, Forenede Stater, 64131
- The University of Kansas Cancer Center-South
-
Kansas City, Missouri, Forenede Stater, 64108
- Truman Medical Centers
-
Lee's Summit, Missouri, Forenede Stater, 64064
- University of Kansas Cancer Center - Lee's Summit
-
Rolla, Missouri, Forenede Stater, 65401
- Delbert Day Cancer Institute at PCRMC
-
Rolla, Missouri, Forenede Stater, 65401
- Mercy Clinic-Rolla-Cancer and Hematology
-
Saint Joseph, Missouri, Forenede Stater, 64506
- Heartland Regional Medical Center
-
Sainte Genevieve, Missouri, Forenede Stater, 63670
- Sainte Genevieve County Memorial Hospital
-
Springfield, Missouri, Forenede Stater, 65807
- CoxHealth South Hospital
-
Springfield, Missouri, Forenede Stater, 65804
- Mercy Hospital Springfield
-
St Louis, Missouri, Forenede Stater, 63110
- Washington University School of Medicine
-
St Louis, Missouri, Forenede Stater, 63129
- Siteman Cancer Center-South County
-
St Louis, Missouri, Forenede Stater, 63131
- Missouri Baptist Medical Center
-
St Louis, Missouri, Forenede Stater, 63141
- Mercy Hospital Saint Louis
-
St Louis, Missouri, Forenede Stater, 63128
- Mercy Hospital South
-
St Louis, Missouri, Forenede Stater, 63109
- Saint Louis Cancer and Breast Institute-South City
-
Sullivan, Missouri, Forenede Stater, 63080
- Missouri Baptist Sullivan Hospital
-
Sunset Hills, Missouri, Forenede Stater, 63127
- Missouri Baptist Outpatient Center-Sunset Hills
-
Washington, Missouri, Forenede Stater, 63090
- Mercy Hospital Washington
-
-
Montana
-
Anaconda, Montana, Forenede Stater, 59711
- Community Hospital of Anaconda
-
Billings, Montana, Forenede Stater, 59101
- Billings Clinic Cancer Center
-
Billings, Montana, Forenede Stater, 59101
- Saint Vincent Healthcare
-
Billings, Montana, Forenede Stater, 59102
- Saint Vincent Frontier Cancer Center
-
Bozeman, Montana, Forenede Stater, 59715
- Bozeman Deaconess Hospital
-
Butte, Montana, Forenede Stater, 59701
- Saint James Community Hospital and Cancer Treatment Center
-
Great Falls, Montana, Forenede Stater, 59405
- Great Falls Clinic
-
Great Falls, Montana, Forenede Stater, 59405
- Benefis Healthcare- Sletten Cancer Institute
-
Helena, Montana, Forenede Stater, 59601
- Saint Peter's Community Hospital
-
Kalispell, Montana, Forenede Stater, 59901
- Kalispell Regional Medical Center
-
Missoula, Montana, Forenede Stater, 59804
- Community Medical Hospital
-
Missoula, Montana, Forenede Stater, 59802
- Saint Patrick Hospital - Community Hospital
-
-
Nebraska
-
Grand Island, Nebraska, Forenede Stater, 68803
- CHI Health Saint Francis
-
Kearney, Nebraska, Forenede Stater, 68847
- CHI Health Good Samaritan
-
Kearney, Nebraska, Forenede Stater, 68845
- Heartland Hematology and Oncology
-
Lincoln, Nebraska, Forenede Stater, 68510
- Saint Elizabeth Regional Medical Center
-
Omaha, Nebraska, Forenede Stater, 68114
- Nebraska Methodist Hospital
-
Omaha, Nebraska, Forenede Stater, 68124
- Alegent Health Bergan Mercy Medical Center
-
Omaha, Nebraska, Forenede Stater, 68122
- Alegent Health Immanuel Medical Center
-
Omaha, Nebraska, Forenede Stater, 68130
- Alegent Health Lakeside Hospital
-
Omaha, Nebraska, Forenede Stater, 68131
- Creighton University Medical Center
-
Omaha, Nebraska, Forenede Stater, 68122
- Hematology and Oncology Consultants PC
-
Papillion, Nebraska, Forenede Stater, 68046
- Midlands Community Hospital
-
-
Nevada
-
Carson City, Nevada, Forenede Stater, 89703
- Carson Tahoe Regional Medical Center
-
Henderson, Nevada, Forenede Stater, 89052
- Comprehensive Cancer Centers of Nevada - Henderson
-
Henderson, Nevada, Forenede Stater, 89052
- OptumCare Cancer Care at Seven Hills
-
Henderson, Nevada, Forenede Stater, 89052
- Cancer and Blood Specialists-Henderson
-
Henderson, Nevada, Forenede Stater, 89052
- Las Vegas Cancer Center-Henderson
-
Henderson, Nevada, Forenede Stater, 89074
- Comprehensive Cancer Centers of Nevada-Southeast Henderson
-
Henderson, Nevada, Forenede Stater, 89074
- 21st Century Oncology-Henderson
-
Henderson, Nevada, Forenede Stater, 89052
- Comprehensive Cancer Centers of Nevada-Horizon Ridge
-
Henderson, Nevada, Forenede Stater, 89074
- Las Vegas Urology - Green Valley
-
Henderson, Nevada, Forenede Stater, 89074
- Las Vegas Urology - Pebble
-
Henderson, Nevada, Forenede Stater, 89074
- Urology Specialists of Nevada - Green Valley
-
Las Vegas, Nevada, Forenede Stater, 89144
- Summerlin Hospital Medical Center
-
Las Vegas, Nevada, Forenede Stater, 89109
- Sunrise Hospital and Medical Center
-
Las Vegas, Nevada, Forenede Stater, 89102
- OptumCare Cancer Care at Charleston
-
Las Vegas, Nevada, Forenede Stater, 89106
- Radiation Oncology Centers of Nevada Central
-
Las Vegas, Nevada, Forenede Stater, 89119
- Radiation Oncology Centers of Nevada Southeast
-
Las Vegas, Nevada, Forenede Stater, 89128
- Comprehensive Cancer Centers of Nevada - Northwest
-
Las Vegas, Nevada, Forenede Stater, 89128
- OptumCare Cancer Care at MountainView
-
Las Vegas, Nevada, Forenede Stater, 89135
- Alliance for Childhood Diseases/Cure 4 the Kids Foundation
-
Las Vegas, Nevada, Forenede Stater, 89144
- Comprehensive Cancer Centers of Nevada - Town Center
-
Las Vegas, Nevada, Forenede Stater, 89144
- Comprehensive Cancer Centers of Nevada-Summerlin
-
Las Vegas, Nevada, Forenede Stater, 89148
- Comprehensive Cancer Centers of Nevada
-
Las Vegas, Nevada, Forenede Stater, 89148
- OptumCare Cancer Care at Fort Apache
-
Las Vegas, Nevada, Forenede Stater, 89169
- Comprehensive Cancer Centers of Nevada - Central Valley
-
Las Vegas, Nevada, Forenede Stater, 89102
- University Medical Center of Southern Nevada
-
Las Vegas, Nevada, Forenede Stater, 89106
- Cancer and Blood Specialists-Shadow
-
Las Vegas, Nevada, Forenede Stater, 89109
- HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway
-
Las Vegas, Nevada, Forenede Stater, 89113
- HealthCare Partners Medical Group Oncology/Hematology-San Martin
-
Las Vegas, Nevada, Forenede Stater, 89128
- Cancer and Blood Specialists-Tenaya
-
Las Vegas, Nevada, Forenede Stater, 89128
- HealthCare Partners Medical Group Oncology/Hematology-Tenaya
-
Las Vegas, Nevada, Forenede Stater, 89148-2405
- Las Vegas Cancer Center-Medical Center
-
Las Vegas, Nevada, Forenede Stater, 89149
- HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills
-
Las Vegas, Nevada, Forenede Stater, 89109
- 21st Century Oncology
-
Las Vegas, Nevada, Forenede Stater, 89128
- 21st Century Oncology-Vegas Tenaya
-
Las Vegas, Nevada, Forenede Stater, 89148
- 21st Century Oncology-Fort Apache
-
Las Vegas, Nevada, Forenede Stater, 89128
- Ann M Wierman MD LTD
-
Las Vegas, Nevada, Forenede Stater, 89074
- Las Vegas Urology - Pecos
-
Las Vegas, Nevada, Forenede Stater, 89102
- Desert West Surgery
-
Las Vegas, Nevada, Forenede Stater, 89103
- Hope Cancer Care of Nevada
-
Las Vegas, Nevada, Forenede Stater, 89106
- Urology Specialists of Nevada - Central
-
Las Vegas, Nevada, Forenede Stater, 89113
- Las Vegas Prostate Cancer Center
-
Las Vegas, Nevada, Forenede Stater, 89113
- Las Vegas Urology - Sunset
-
Las Vegas, Nevada, Forenede Stater, 89128
- Las Vegas Urology - Cathedral Rock
-
Las Vegas, Nevada, Forenede Stater, 89128
- Las Vegas Urology - Smoke Ranch
-
Las Vegas, Nevada, Forenede Stater, 89128
- Urology Specialists of Nevada - Northwest
-
Las Vegas, Nevada, Forenede Stater, 89148
- Urology Specialists of Nevada - Southwest
-
Las Vegas, Nevada, Forenede Stater, 89169
- University Cancer Center
-
Pahrump, Nevada, Forenede Stater, 89048
- Hope Cancer Care of Nevada-Pahrump
-
Reno, Nevada, Forenede Stater, 89502
- Renown Regional Medical Center
-
Reno, Nevada, Forenede Stater, 89503
- Saint Mary's Regional Medical Center
-
Reno, Nevada, Forenede Stater, 89509
- Radiation Oncology Associates
-
-
New Hampshire
-
Exeter, New Hampshire, Forenede Stater, 03833
- Exeter Hospital
-
-
New Jersey
-
Basking Ridge, New Jersey, Forenede Stater, 07920
- Memorial Sloan Kettering Basking Ridge
-
Hamilton, New Jersey, Forenede Stater, 08690
- The Cancer Institute of New Jersey Hamilton
-
Livingston, New Jersey, Forenede Stater, 07039
- Saint Barnabas Medical Center
-
Middletown, New Jersey, Forenede Stater, 07748
- Memorial Sloan Kettering Monmouth
-
Montvale, New Jersey, Forenede Stater, 07645
- Memorial Sloan Kettering Bergen
-
Moorestown, New Jersey, Forenede Stater, 08057
- Virtua Samson Cancer Center
-
Mount Holly, New Jersey, Forenede Stater, 08060
- Virtua Memorial
-
New Brunswick, New Jersey, Forenede Stater, 08903
- Rutgers Cancer Institute of New Jersey
-
Newark, New Jersey, Forenede Stater, 07101
- Rutgers New Jersey Medical School
-
Sewell, New Jersey, Forenede Stater, 08080
- Kennedy Health Systems-Cancer Center
-
Somerville, New Jersey, Forenede Stater, 08876
- Robert Wood Johnson University Hospital Somerset
-
Summit, New Jersey, Forenede Stater, 07902
- Overlook Hospital
-
Toms River, New Jersey, Forenede Stater, 08755
- Community Medical Center
-
Voorhees Township, New Jersey, Forenede Stater, 08043
- Virtua Voorhees
-
-
New Mexico
-
Albuquerque, New Mexico, Forenede Stater, 87102
- University of New Mexico Cancer Center
-
Albuquerque, New Mexico, Forenede Stater, 87109
- Lovelace Radiation Oncology
-
Albuquerque, New Mexico, Forenede Stater, 87109
- New Mexico Oncology Hematology Consultants
-
-
New York
-
Auburn, New York, Forenede Stater, 13021
- Hematology Oncology Associates of Central New York-Auburn
-
Bay Shore, New York, Forenede Stater, 11706
- Northwell Health Imbert Cancer Center
-
Brooklyn, New York, Forenede Stater, 11215
- New York-Presbyterian/Brooklyn Methodist Hospital
-
Canandiaqua, New York, Forenede Stater, 14424
- Sands Cancer Center
-
Commack, New York, Forenede Stater, 11725
- Memorial Sloan Kettering Commack
-
Cooperstown, New York, Forenede Stater, 13326
- Mary Imogene Bassett Hospital
-
East Syracuse, New York, Forenede Stater, 13057
- Hematology Oncology Associates of Central New York-East Syracuse
-
East White Plains, New York, Forenede Stater, 10604
- Memorial Sloan Kettering Westchester
-
Elmira, New York, Forenede Stater, 14905
- Arnot Ogden Medical Center/Falck Cancer Center
-
Glens Falls, New York, Forenede Stater, 12801
- Glens Falls Hospital
-
Lake Success, New York, Forenede Stater, 11042
- Northwell Health/Center for Advanced Medicine
-
Mount Kisco, New York, Forenede Stater, 10549
- Northern Westchester Hospital
-
New York, New York, Forenede Stater, 10065
- Memorial Sloan Kettering Cancer Center
-
New York, New York, Forenede Stater, 10032
- NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
-
New York, New York, Forenede Stater, 10016
- Laura and Isaac Perlmutter Cancer Center at NYU Langone
-
New York, New York, Forenede Stater, 10021
- Lenox Hill Hospital
-
Oneida, New York, Forenede Stater, 13421
- Upstate Cancer Center Radiation Oncology at Oneida
-
Oswego, New York, Forenede Stater, 13126
- Upstate Cancer Center Radiation Oncology at Oswego
-
Rochester, New York, Forenede Stater, 14642
- University of Rochester
-
Rochester, New York, Forenede Stater, 14620
- Highland Hospital
-
Rochester, New York, Forenede Stater, 14606
- Wilmot Cancer Institute Radiation Oncology at Greece
-
Sleepy Hollow, New York, Forenede Stater, 10591
- Phelps Memorial Hospital Center
-
Staten Island, New York, Forenede Stater, 10305
- Staten Island University Hospital
-
Stony Brook, New York, Forenede Stater, 11794
- Stony Brook University Medical Center
-
Syracuse, New York, Forenede Stater, 13210
- State University of New York Upstate Medical University
-
Syracuse, New York, Forenede Stater, 13215
- Hematology Oncology Associates of Central New York-Onondaga Hill
-
Syracuse, New York, Forenede Stater, 13215
- SUNY Upstate Medical Center-Community Campus
-
Syracuse, New York, Forenede Stater, 13210
- Upstate Cancer Center at Hill Radiation Oncology
-
The Bronx, New York, Forenede Stater, 10461
- Montefiore Medical Center-Einstein Campus
-
The Bronx, New York, Forenede Stater, 10467
- Montefiore Medical Center - Moses Campus
-
The Bronx, New York, Forenede Stater, 10461
- Montefiore Medical Center-Weiler Hospital
-
Uniondale, New York, Forenede Stater, 11553
- Memorial Sloan Kettering Nassau
-
-
North Dakota
-
Bismarck, North Dakota, Forenede Stater, 58501
- Sanford Bismarck Medical Center
-
Fargo, North Dakota, Forenede Stater, 58122
- Sanford Roger Maris Cancer Center
-
Fargo, North Dakota, Forenede Stater, 58103
- Essentia Health Cancer Center-South University Clinic
-
Fargo, North Dakota, Forenede Stater, 58122
- Sanford Broadway Medical Center
-
Fargo, North Dakota, Forenede Stater, 58103
- Sanford South University Medical Center
-
Grand Forks, North Dakota, Forenede Stater, 58201
- Altru Cancer Center
-
Jamestown, North Dakota, Forenede Stater, 58401
- Essentia Health - Jamestown Clinic
-
-
Ohio
-
Akron, Ohio, Forenede Stater, 44307
- Cleveland Clinic Akron General
-
Beachwood, Ohio, Forenede Stater, 44122
- UHHS-Chagrin Highlands Medical Center
-
Belpre, Ohio, Forenede Stater, 45714
- Strecker Cancer Center-Belpre
-
Chardon, Ohio, Forenede Stater, 44024
- Geauga Hospital
-
Chillicothe, Ohio, Forenede Stater, 45601
- Adena Regional Medical Center
-
Cincinnati, Ohio, Forenede Stater, 45219
- University of Cincinnati Cancer Center-UC Medical Center
-
Cincinnati, Ohio, Forenede Stater, 45220
- Good Samaritan Hospital - Cincinnati
-
Cincinnati, Ohio, Forenede Stater, 45242
- Bethesda North Hospital
-
Cincinnati, Ohio, Forenede Stater, 45247
- TriHealth Cancer Institute-Westside
-
Cincinnati, Ohio, Forenede Stater, 45255
- TriHealth Cancer Institute-Anderson
-
Cleveland, Ohio, Forenede Stater, 44106
- Case Western Reserve University
-
Cleveland, Ohio, Forenede Stater, 44195
- Cleveland Clinic Foundation
-
Cleveland, Ohio, Forenede Stater, 44111
- Cleveland Clinic Cancer Center/Fairview Hospital
-
Columbus, Ohio, Forenede Stater, 43214
- Riverside Methodist Hospital
-
Columbus, Ohio, Forenede Stater, 43210
- Ohio State University Comprehensive Cancer Center
-
Columbus, Ohio, Forenede Stater, 43219
- The Mark H Zangmeister Center
-
Columbus, Ohio, Forenede Stater, 43214
- Columbus Oncology and Hematology Associates Inc
-
Columbus, Ohio, Forenede Stater, 43228
- Doctors Hospital
-
Columbus, Ohio, Forenede Stater, 43213
- Mount Carmel East Hospital
-
Columbus, Ohio, Forenede Stater, 43215
- Grant Medical Center
-
Columbus, Ohio, Forenede Stater, 43222
- Mount Carmel Health Center West
-
Delaware, Ohio, Forenede Stater, 43015
- Delaware Health Center-Grady Cancer Center
-
Delaware, Ohio, Forenede Stater, 43015
- Delaware Radiation Oncology
-
Delaware, Ohio, Forenede Stater, 43015
- Grady Memorial Hospital
-
Dublin, Ohio, Forenede Stater, 43016
- Dublin Methodist Hospital
-
Elyria, Ohio, Forenede Stater, 44035
- Mercy Cancer Center-Elyria
-
Grove City, Ohio, Forenede Stater, 43123
- Mount Carmel Grove City Hospital
-
Independence, Ohio, Forenede Stater, 44131
- Cleveland Clinic Cancer Center Independence
-
Lancaster, Ohio, Forenede Stater, 43130
- Fairfield Medical Center
-
Lima, Ohio, Forenede Stater, 45801
- Saint Rita's Medical Center
-
Mansfield, Ohio, Forenede Stater, 44906
- Cleveland Clinic Cancer Center Mansfield
-
Mansfield, Ohio, Forenede Stater, 44903
- OhioHealth Mansfield Hospital
-
Marietta, Ohio, Forenede Stater, 45750
- Marietta Memorial Hospital
-
Marion, Ohio, Forenede Stater, 43302
- OhioHealth Marion General Hospital
-
Mayfield Heights, Ohio, Forenede Stater, 44124
- Hillcrest Hospital Cancer Center
-
Mayfield Heights, Ohio, Forenede Stater, 44124
- UH Seidman Cancer Center at Landerbrook Health Center
-
Middleburg Heights, Ohio, Forenede Stater, 44130
- UH Seidman Cancer Center at Southwest General Hospital
-
Mount Vernon, Ohio, Forenede Stater, 43050
- Knox Community Hospital
-
Newark, Ohio, Forenede Stater, 43055
- Licking Memorial Hospital
-
Newark, Ohio, Forenede Stater, 43055
- Newark Radiation Oncology
-
Perrysburg, Ohio, Forenede Stater, 43551
- Mercy Health Perrysburg Cancer Center
-
Portsmouth, Ohio, Forenede Stater, 45662
- Southern Ohio Medical Center
-
Ravenna, Ohio, Forenede Stater, 44266
- University Hospitals Portage Medical Center
-
Sandusky, Ohio, Forenede Stater, 44870
- North Coast Cancer Care
-
Sandusky, Ohio, Forenede Stater, 44870
- UH Seidman Cancer Center at Firelands Regional Medical Center
-
Strongsville, Ohio, Forenede Stater, 44136
- Cleveland Clinic Cancer Center Strongsville
-
Toledo, Ohio, Forenede Stater, 43608
- Saint Vincent Mercy Medical Center
-
Toledo, Ohio, Forenede Stater, 43623
- Mercy Health - Saint Anne Hospital
-
West Chester, Ohio, Forenede Stater, 45069
- University of Cincinnati Cancer Center-West Chester
-
Westerville, Ohio, Forenede Stater, 43081
- Saint Ann's Hospital
-
Westlake, Ohio, Forenede Stater, 44145
- UHHS-Westlake Medical Center
-
Wooster, Ohio, Forenede Stater, 44691
- Cleveland Clinic Wooster Family Health and Surgery Center
-
Zanesville, Ohio, Forenede Stater, 43701
- Genesis Healthcare System Cancer Care Center
-
-
Oklahoma
-
Oklahoma City, Oklahoma, Forenede Stater, 73104
- University of Oklahoma Health Sciences Center
-
Oklahoma City, Oklahoma, Forenede Stater, 73120
- Mercy Hospital Oklahoma City
-
-
Oregon
-
Baker City, Oregon, Forenede Stater, 97814
- Saint Alphonsus Medical Center-Baker City
-
Bend, Oregon, Forenede Stater, 97701
- Saint Charles Health System
-
Clackamas, Oregon, Forenede Stater, 97015
- Clackamas Radiation Oncology Center
-
Clackamas, Oregon, Forenede Stater, 97015
- Providence Cancer Institute Clackamas Clinic
-
Coos Bay, Oregon, Forenede Stater, 97420
- Bay Area Hospital
-
Gresham, Oregon, Forenede Stater, 97030
- Legacy Mount Hood Medical Center
-
Newberg, Oregon, Forenede Stater, 97132
- Providence Newberg Medical Center
-
Ontario, Oregon, Forenede Stater, 97914
- Saint Alphonsus Medical Center-Ontario
-
Portland, Oregon, Forenede Stater, 97239
- Oregon Health and Science University
-
Portland, Oregon, Forenede Stater, 97210
- Legacy Good Samaritan Hospital and Medical Center
-
Portland, Oregon, Forenede Stater, 97213
- Providence Portland Medical Center
-
Portland, Oregon, Forenede Stater, 97225
- Providence Saint Vincent Medical Center
-
Redmond, Oregon, Forenede Stater, 97756
- Saint Charles Health System-Redmond
-
Tualatin, Oregon, Forenede Stater, 97062
- Legacy Meridian Park Hospital
-
-
Pennsylvania
-
Altoona, Pennsylvania, Forenede Stater, 16601
- UPMC Altoona
-
Beaver, Pennsylvania, Forenede Stater, 15009
- UPMC-Heritage Valley Health System Beaver
-
Bethlehem, Pennsylvania, Forenede Stater, 18015
- Saint Luke's University Hospital-Bethlehem Campus
-
Carlisle, Pennsylvania, Forenede Stater, 17015
- Carlisle Regional Cancer Center
-
Chadds Ford, Pennsylvania, Forenede Stater, 19317
- Christiana Care Health System-Concord Health Center
-
Danville, Pennsylvania, Forenede Stater, 17822
- Geisinger Medical Center
-
Dunmore, Pennsylvania, Forenede Stater, 18512
- Northeast Radiation Oncology Center
-
Ephrata, Pennsylvania, Forenede Stater, 17522
- Ephrata Cancer Center
-
Ephrata, Pennsylvania, Forenede Stater, 17522
- Ephrata Community Hospital
-
Farrell, Pennsylvania, Forenede Stater, 16121
- UPMC Cancer Center at UPMC Horizon
-
Gettysburg, Pennsylvania, Forenede Stater, 17325
- Adams Cancer Center
-
Greensburg, Pennsylvania, Forenede Stater, 15601
- UPMC Cancer Centers - Arnold Palmer Pavilion
-
Hanover, Pennsylvania, Forenede Stater, 17331
- Cherry Tree Cancer Center
-
Harrisburg, Pennsylvania, Forenede Stater, 17109
- UPMC Pinnacle Cancer Center/Community Osteopathic Campus
-
Harrisburg, Pennsylvania, Forenede Stater, 17101
- UPMC Pinnacle Harrisburg
-
Hazleton, Pennsylvania, Forenede Stater, 18201
- Geisinger Medical Center-Cancer Center Hazleton
-
Jefferson Hills, Pennsylvania, Forenede Stater, 15025
- Jefferson Hospital
-
Johnstown, Pennsylvania, Forenede Stater, 15901
- UPMC-Johnstown/John P. Murtha Regional Cancer Center
-
Lebanon, Pennsylvania, Forenede Stater, 17042
- Sechler Family Cancer Center
-
Lewisburg, Pennsylvania, Forenede Stater, 17837
- Geisinger Medical Oncology-Lewisburg
-
Lewistown, Pennsylvania, Forenede Stater, 17044
- Lewistown Hospital
-
McKeesport, Pennsylvania, Forenede Stater, 15132
- UPMC Cancer Center at UPMC McKeesport
-
Meadowbrook, Pennsylvania, Forenede Stater, 19046
- Holy Redeemer Hospital and Medical Center
-
Mechanicsburg, Pennsylvania, Forenede Stater, 17050
- UPMC Pinnacle West Shore
-
Monroeville, Pennsylvania, Forenede Stater, 15146
- Intercommunity Cancer Center
-
Monroeville, Pennsylvania, Forenede Stater, 15146
- Forbes Hospital
-
Monroeville, Pennsylvania, Forenede Stater, 15146
- UPMC Cancer Center - Monroeville
-
Moon Township, Pennsylvania, Forenede Stater, 15108
- UPMC-Coraopolis/Heritage Valley Radiation Oncology
-
New Castle, Pennsylvania, Forenede Stater, 16105
- UPMC Jameson
-
Philadelphia, Pennsylvania, Forenede Stater, 19111
- Fox Chase Cancer Center
-
Philadelphia, Pennsylvania, Forenede Stater, 19107
- Thomas Jefferson University Hospital
-
Philadelphia, Pennsylvania, Forenede Stater, 19114
- Aria Health-Torresdale Campus
-
Pittsburgh, Pennsylvania, Forenede Stater, 15212
- Allegheny General Hospital
-
Pittsburgh, Pennsylvania, Forenede Stater, 15224
- West Penn Hospital
-
Pittsburgh, Pennsylvania, Forenede Stater, 15213
- UPMC-Magee Womens Hospital
-
Pittsburgh, Pennsylvania, Forenede Stater, 15232
- University of Pittsburgh Cancer Institute (UPCI)
-
Pittsburgh, Pennsylvania, Forenede Stater, 15232
- UPMC-Shadyside Hospital
-
Pittsburgh, Pennsylvania, Forenede Stater, 15213
- UPMC-Presbyterian Hospital
-
Pittsburgh, Pennsylvania, Forenede Stater, 15215
- UPMC-Saint Margaret
-
Pittsburgh, Pennsylvania, Forenede Stater, 15237
- UPMC-Passavant Hospital
-
Pittsburgh, Pennsylvania, Forenede Stater, 15243
- UPMC-Saint Clair Hospital Cancer Center
-
Pottsville, Pennsylvania, Forenede Stater, 17901
- Geisinger Cancer Services-Pottsville
-
Sayre, Pennsylvania, Forenede Stater, 18840
- Guthrie Medical Group PC-Robert Packer Hospital
-
Scranton, Pennsylvania, Forenede Stater, 18510
- Community Medical Center
-
Seneca, Pennsylvania, Forenede Stater, 16346
- UPMC Cancer Center at UPMC Northwest
-
Uniontown, Pennsylvania, Forenede Stater, 15401
- UPMC Uniontown Hospital Radiation Oncology
-
Washington, Pennsylvania, Forenede Stater, 15301
- UPMC Washington Hospital Radiation Oncology
-
West Reading, Pennsylvania, Forenede Stater, 19611
- Reading Hospital
-
Wexford, Pennsylvania, Forenede Stater, 15090
- Wexford Health and Wellness Pavilion
-
Wilkes-Barre, Pennsylvania, Forenede Stater, 18711
- Geisinger Wyoming Valley/Henry Cancer Center
-
Willow Grove, Pennsylvania, Forenede Stater, 19090
- Abington Memorial Hospital-Asplundh Cancer Pavilion
-
York, Pennsylvania, Forenede Stater, 17403
- WellSpan Health-York Cancer Center
-
York, Pennsylvania, Forenede Stater, 17403
- WellSpan Health-York Hospital
-
York, Pennsylvania, Forenede Stater, 17408
- UPMC Memorial
-
-
South Carolina
-
Bluffton, South Carolina, Forenede Stater, 29910
- Saint Joseph's/Candler - Bluffton Campus
-
Boiling Springs, South Carolina, Forenede Stater, 29316
- Prisma Health Cancer Institute - Spartanburg
-
Charleston, South Carolina, Forenede Stater, 29425
- Medical University of South Carolina
-
Gaffney, South Carolina, Forenede Stater, 29341
- Gibbs Cancer Center-Gaffney
-
Greenville, South Carolina, Forenede Stater, 29605
- Prisma Health Cancer Institute - Faris
-
Greenville, South Carolina, Forenede Stater, 29607
- Saint Francis Cancer Center
-
Greenville, South Carolina, Forenede Stater, 29615
- Prisma Health Cancer Institute - Eastside
-
Greenville, South Carolina, Forenede Stater, 29601
- Saint Francis Hospital
-
Greer, South Carolina, Forenede Stater, 29650
- Prisma Health Cancer Institute - Greer
-
Greer, South Carolina, Forenede Stater, 29651
- Gibbs Cancer Center-Pelham
-
Hilton Head Island, South Carolina, Forenede Stater, 29926
- The Radiation Oncology Center-Hilton Head/Bluffton
-
Hilton Head Island, South Carolina, Forenede Stater, 29926-3827
- South Carolina Cancer Specialists PC
-
Seneca, South Carolina, Forenede Stater, 29672
- Prisma Health Cancer Institute - Seneca
-
Spartanburg, South Carolina, Forenede Stater, 29303
- Spartanburg Medical Center
-
Spartanburg, South Carolina, Forenede Stater, 29307
- Spartanburg Medical Center - Mary Black Campus
-
Union, South Carolina, Forenede Stater, 29379
- MGC Hematology Oncology-Union
-
-
South Dakota
-
Sioux Falls, South Dakota, Forenede Stater, 57117-5134
- Sanford USD Medical Center - Sioux Falls
-
Sioux Falls, South Dakota, Forenede Stater, 57104
- Sanford Cancer Center Oncology Clinic
-
-
Tennessee
-
Bristol, Tennessee, Forenede Stater, 37620
- Wellmont Bristol Regional Medical Center
-
Chattanooga, Tennessee, Forenede Stater, 37404
- Memorial Hospital
-
Chattanooga, Tennessee, Forenede Stater, 37403
- Erlanger Medical Center
-
Franklin, Tennessee, Forenede Stater, 37067
- Vanderbilt-Ingram Cancer Center Cool Springs
-
Franklin, Tennessee, Forenede Stater, 37067
- Vanderbilt-Ingram Cancer Center at Franklin
-
Germantown, Tennessee, Forenede Stater, 38138
- The West Clinic - Wolf River
-
Hixson, Tennessee, Forenede Stater, 37343
- Pulmonary Medicine Center of Chattanooga-Hixson
-
Johnson City, Tennessee, Forenede Stater, 37604
- Wellmont Medical Associates Oncology and Hematology-Johnson City
-
Kingsport, Tennessee, Forenede Stater, 37660
- Wellmont Holston Valley Hospital and Medical Center
-
Kingsport, Tennessee, Forenede Stater, 37660
- Regional Cancer Center at Indian Path Community Hospital
-
Memphis, Tennessee, Forenede Stater, 38120
- Baptist Memorial Hospital and Cancer Center-Memphis
-
Memphis, Tennessee, Forenede Stater, 38104
- The West Clinic - Mid-Town
-
Nashville, Tennessee, Forenede Stater, 37232
- Vanderbilt University/Ingram Cancer Center
-
Nashville, Tennessee, Forenede Stater, 37204
- Vanderbilt Breast Center at One Hundred Oaks
-
Ooltewah, Tennessee, Forenede Stater, 37363
- Memorial GYN Plus
-
-
Texas
-
Bryan, Texas, Forenede Stater, 77802
- Saint Joseph Regional Cancer Center
-
Galveston, Texas, Forenede Stater, 77555-0565
- University of Texas Medical Branch
-
Houston, Texas, Forenede Stater, 77030
- Ben Taub General Hospital
-
-
Utah
-
American Fork, Utah, Forenede Stater, 84003
- American Fork Hospital / Huntsman Intermountain Cancer Center
-
Cedar City, Utah, Forenede Stater, 84720
- Sandra L Maxwell Cancer Center
-
Farmington, Utah, Forenede Stater, 84025
- Farmington Health Center
-
Logan, Utah, Forenede Stater, 84321
- Logan Regional Hospital
-
Murray, Utah, Forenede Stater, 84107
- Intermountain Medical Center
-
Ogden, Utah, Forenede Stater, 84403
- McKay-Dee Hospital Center
-
Ogden, Utah, Forenede Stater, 84405
- Ogden Regional Medical Center
-
Provo, Utah, Forenede Stater, 84604
- Utah Valley Regional Medical Center
-
Riverton, Utah, Forenede Stater, 84065
- Riverton Hospital
-
Salt Lake City, Utah, Forenede Stater, 84112
- Huntsman Cancer Institute/University of Utah
-
Salt Lake City, Utah, Forenede Stater, 84106
- Utah Cancer Specialists-Salt Lake City
-
Salt Lake City, Utah, Forenede Stater, 84143
- LDS Hospital
-
Salt Lake City, Utah, Forenede Stater, 84106
- University of Utah Sugarhouse Health Center
-
South Jordan, Utah, Forenede Stater, 84009
- South Jordan Health Center
-
St. George, Utah, Forenede Stater, 84770
- Dixie Medical Center Regional Cancer Center
-
-
Vermont
-
Berlin Corners, Vermont, Forenede Stater, 05602
- Central Vermont Medical Center/National Life Cancer Treatment
-
Burlington, Vermont, Forenede Stater, 05401
- University of Vermont Medical Center
-
Burlington, Vermont, Forenede Stater, 05405
- University of Vermont and State Agricultural College
-
-
Virginia
-
Alexandria, Virginia, Forenede Stater, 22304
- Inova Alexandria Hospital
-
Bristol, Virginia, Forenede Stater, 24201
- Wellmont Medical Associates-Bristol
-
Fairfax, Virginia, Forenede Stater, 22031
- Inova Schar Cancer Institute
-
Fairfax, Virginia, Forenede Stater, 22033
- Inova Fair Oaks Hospital
-
Falls Church, Virginia, Forenede Stater, 22042
- Inova Fairfax Hospital
-
Leesburg, Virginia, Forenede Stater, 20176
- Inova Loudoun Hospital
-
Mechanicsville, Virginia, Forenede Stater, 23116
- VCU Massey Cancer Center at Hanover Medical Park
-
Norton, Virginia, Forenede Stater, 24273
- Southwest VA Regional Cancer Center
-
Portsmouth, Virginia, Forenede Stater, 23708-2197
- Naval Medical Center - Portsmouth
-
Richmond, Virginia, Forenede Stater, 23235
- VCU Massey Cancer Center at Stony Point
-
Richmond, Virginia, Forenede Stater, 23298
- Virginia Commonwealth University/Massey Cancer Center
-
-
Washington
-
Aberdeen, Washington, Forenede Stater, 98520
- Providence Regional Cancer System-Aberdeen
-
Auburn, Washington, Forenede Stater, 98001
- MultiCare Auburn Medical Center
-
Bellevue, Washington, Forenede Stater, 98004
- Overlake Medical Center
-
Bellingham, Washington, Forenede Stater, 98225
- PeaceHealth Saint Joseph Medical Center
-
Bremerton, Washington, Forenede Stater, 98310
- Harrison HealthPartners Hematology and Oncology-Bremerton
-
Bremerton, Washington, Forenede Stater, 98310
- Harrison Medical Center
-
Burien, Washington, Forenede Stater, 98166
- Highline Medical Center-Main Campus
-
Centralia, Washington, Forenede Stater, 98531
- Providence Regional Cancer System-Centralia
-
Edmonds, Washington, Forenede Stater, 98026
- Swedish Cancer Institute-Edmonds
-
Enumclaw, Washington, Forenede Stater, 98022
- Saint Elizabeth Hospital
-
Everett, Washington, Forenede Stater, 98201
- Providence Regional Cancer Partnership
-
Federal Way, Washington, Forenede Stater, 98003
- Saint Francis Hospital
-
Gig Harbor, Washington, Forenede Stater, 98335
- MultiCare Gig Harbor Medical Park
-
Issaquah, Washington, Forenede Stater, 98029
- Swedish Cancer Institute-Issaquah
-
Kennewick, Washington, Forenede Stater, 99336
- Kadlec Clinic Hematology and Oncology
-
Lacey, Washington, Forenede Stater, 98503
- Providence Regional Cancer System-Lacey
-
Lakewood, Washington, Forenede Stater, 98499
- Saint Clare Hospital
-
Longview, Washington, Forenede Stater, 98632
- PeaceHealth Saint John Medical Center
-
Port Townsend, Washington, Forenede Stater, 98368
- Jefferson Healthcare
-
Poulsbo, Washington, Forenede Stater, 98370
- Harrison HealthPartners Hematology and Oncology-Poulsbo
-
Puyallup, Washington, Forenede Stater, 98372
- MultiCare Good Samaritan Hospital
-
Renton, Washington, Forenede Stater, 98055
- Valley Medical Center
-
Seattle, Washington, Forenede Stater, 98107
- Swedish Medical Center-Ballard Campus
-
Seattle, Washington, Forenede Stater, 98112
- Kaiser Permanente Washington
-
Seattle, Washington, Forenede Stater, 98104
- Pacific Gynecology Specialists
-
Seattle, Washington, Forenede Stater, 98122-4307
- Swedish Medical Center-First Hill
-
Seattle, Washington, Forenede Stater, 98122-5711
- Swedish Medical Center-Cherry Hill
-
Sedro-Woolley, Washington, Forenede Stater, 98284
- PeaceHealth United General Medical Center
-
Shelton, Washington, Forenede Stater, 98584
- Providence Regional Cancer System-Shelton
-
Spokane, Washington, Forenede Stater, 99204
- MultiCare Deaconess Cancer and Blood Specialty Center - Downtown
-
Spokane, Washington, Forenede Stater, 99218
- MultiCare Deaconess Cancer and Blood Specialty Center - North
-
Spokane Valley, Washington, Forenede Stater, 99216
- MultiCare Deaconess Cancer and Blood Specialty Center - Valley
-
Tacoma, Washington, Forenede Stater, 98405
- Mary Bridge Children's Hospital and Health Center
-
Tacoma, Washington, Forenede Stater, 98405
- Northwest Medical Specialties PLLC
-
Tacoma, Washington, Forenede Stater, 98405
- MultiCare Tacoma General Hospital
-
Tacoma, Washington, Forenede Stater, 98405
- Franciscan Research Center-Northwest Medical Plaza
-
Vancouver, Washington, Forenede Stater, 98686
- Legacy Salmon Creek Hospital
-
Vancouver, Washington, Forenede Stater, 98664
- PeaceHealth Southwest Medical Center
-
Vancouver, Washington, Forenede Stater, 98684
- Legacy Cancer Institute Medical Oncology and Day Treatment
-
Walla Walla, Washington, Forenede Stater, 99362
- Providence Saint Mary Regional Cancer Center
-
Yakima, Washington, Forenede Stater, 98902
- North Star Lodge Cancer Center at Yakima Valley Memorial Hospital
-
Yelm, Washington, Forenede Stater, 98597
- Providence Regional Cancer System-Yelm
-
-
West Virginia
-
Charleston, West Virginia, Forenede Stater, 25304
- West Virginia University Charleston Division
-
-
Wisconsin
-
Ashland, Wisconsin, Forenede Stater, 54806
- Duluth Clinic Ashland
-
Ashland, Wisconsin, Forenede Stater, 54806
- Northwest Wisconsin Cancer Center
-
Brookfield, Wisconsin, Forenede Stater, 53045
- Ascension Southeast Wisconsin Hospital - Elmbrook Campus
-
Burlington, Wisconsin, Forenede Stater, 53105
- Aurora Cancer Care-Southern Lakes VLCC
-
Eau Claire, Wisconsin, Forenede Stater, 54701
- HSHS Sacred Heart Hospital
-
Eau Claire, Wisconsin, Forenede Stater, 54701
- Mayo Clinic Health System-Eau Claire Clinic
-
Fond du Lac, Wisconsin, Forenede Stater, 54937
- Aurora Health Center-Fond du Lac
-
Fond du Lac, Wisconsin, Forenede Stater, 54935
- Saint Agnes Hospital/Agnesian Cancer Center
-
Franklin, Wisconsin, Forenede Stater, 53132
- Ascension Saint Francis - Reiman Cancer Center
-
Germantown, Wisconsin, Forenede Stater, 53022
- Aurora Health Care Germantown Health Center
-
Grafton, Wisconsin, Forenede Stater, 53024
- Aurora Cancer Care-Grafton
-
Green Bay, Wisconsin, Forenede Stater, 54311
- Aurora BayCare Medical Center
-
Green Bay, Wisconsin, Forenede Stater, 54301
- Saint Vincent Hospital Cancer Center Green Bay
-
Green Bay, Wisconsin, Forenede Stater, 54303
- Saint Vincent Hospital Cancer Center at Saint Mary's
-
Johnson Creek, Wisconsin, Forenede Stater, 53038
- UW Cancer Center Johnson Creek
-
Kenosha, Wisconsin, Forenede Stater, 53142
- Aurora Cancer Care-Kenosha South
-
La Crosse, Wisconsin, Forenede Stater, 54601
- Gundersen Lutheran Medical Center
-
La Crosse, Wisconsin, Forenede Stater, 54601
- Mayo Clinic Health System-Franciscan Healthcare
-
Madison, Wisconsin, Forenede Stater, 53792
- University of Wisconsin Hospital and Clinics
-
Manitowoc, Wisconsin, Forenede Stater, 54221
- Holy Family Memorial Hospital
-
Marinette, Wisconsin, Forenede Stater, 54143
- Aurora Bay Area Medical Group-Marinette
-
Marinette, Wisconsin, Forenede Stater, 54143
- Saint Vincent Hospital Cancer Center at Marinette
-
Menomonee Falls, Wisconsin, Forenede Stater, 53051
- Froedtert Menomonee Falls Hospital
-
Mequon, Wisconsin, Forenede Stater, 53097
- Ascension Columbia Saint Mary's Hospital Ozaukee
-
Milwaukee, Wisconsin, Forenede Stater, 53226
- Medical College of Wisconsin
-
Milwaukee, Wisconsin, Forenede Stater, 53209
- Aurora Cancer Care-Milwaukee
-
Milwaukee, Wisconsin, Forenede Stater, 53215
- Aurora Saint Luke's Medical Center
-
Milwaukee, Wisconsin, Forenede Stater, 53233
- Aurora Sinai Medical Center
-
Milwaukee, Wisconsin, Forenede Stater, 53211
- Ascension Columbia Saint Mary's Hospital - Milwaukee
-
New Richmond, Wisconsin, Forenede Stater, 54017
- Cancer Center of Western Wisconsin
-
Oconto Falls, Wisconsin, Forenede Stater, 54154
- Saint Vincent Hospital Cancer Center at Oconto Falls
-
Oshkosh, Wisconsin, Forenede Stater, 54904
- Vince Lombardi Cancer Clinic - Oshkosh
-
Racine, Wisconsin, Forenede Stater, 53406
- Aurora Cancer Care-Racine
-
Racine, Wisconsin, Forenede Stater, 53405
- Ascension All Saints Hospital
-
Sheboygan, Wisconsin, Forenede Stater, 53081
- Vince Lombardi Cancer Clinic-Sheboygan
-
Sheboygan, Wisconsin, Forenede Stater, 53081
- HSHS Saint Nicholas Hospital
-
Sturgeon Bay, Wisconsin, Forenede Stater, 54235-1495
- Saint Vincent Hospital Cancer Center at Sturgeon Bay
-
Summit, Wisconsin, Forenede Stater, 53066
- Aurora Medical Center in Summit
-
Two Rivers, Wisconsin, Forenede Stater, 54241
- Vince Lombardi Cancer Clinic-Two Rivers
-
Wauwatosa, Wisconsin, Forenede Stater, 53226
- Aurora Cancer Care-Milwaukee West
-
West Allis, Wisconsin, Forenede Stater, 53227
- Aurora West Allis Medical Center
-
West Bend, Wisconsin, Forenede Stater, 53095
- Froedtert West Bend Hospital/Kraemer Cancer Center
-
Wisconsin Rapids, Wisconsin, Forenede Stater, 54494
- Aspirus Cancer Care - Wisconsin Rapids
-
-
Wyoming
-
Cheyenne, Wyoming, Forenede Stater, 82001
- Cheyenne Regional Medical Center-West
-
Cody, Wyoming, Forenede Stater, 82414
- Billings Clinic-Cody
-
Sheridan, Wyoming, Forenede Stater, 82801
- Welch Cancer Center
-
-
Deltagelseskriterier
Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.
Berettigelseskriterier
Aldre berettiget til at studere
18 år og ældre (Voksen, Ældre voksen)
Tager imod sunde frivillige
Ingen
Beskrivelse
Inklusionskriterier:
- Histologisk bekræftet invasivt karcinom i brystet af en hvilken som helst af følgende histologier (duktal, lobulær, mammary, medullær eller tubulær); patienter med metaplastisk brystkræft er ikke berettigede
Patienterne vil blive iscenesat i henhold til TNM-stadiesystemet
- For patienter, der ikke modtager neoadjuverende kemoterapi, skal patologisk stadie være T0N1-2a, T1N1-2a, T2N1-2a, T3N0-2a og alle M0-status
- For patienter, der modtager neoadjuverende kemoterapi, er klinisk præ-kemo-stadieinddeling og patologisk post-mastektomi påkrævet for alle patienter; patienter, der har modtaget neoadjuverende kemoterapi og patologisk er cT0-2 og N0, er kun kvalificerede, hvis biopsi-bevist klinisk N1- eller N2-sygdom er dokumenteret før starten af neoadjuverende kemoterapi; cT3N0-patienter eller ypT3N0-patienter, der modtager neoadjuverende kemoterapi, kan være berettigede baseret på klinisk eller patologisk T-stadie og kræver ikke patologisk positive lymfeknuder
- Bemærk: Højere af det kliniske eller patologiske T- og N-stadium bruges til endelig stadie, hvis de modtager neoadjuverende kemoterapi; alle patienter med klinisk, radiografisk eller patologisk T4, N3 eller involveret intern brystsygdom (N1b, N1c og N2b) er ikke kvalificerede. N1mic-patienter er berettigede.
- Ingen forudgående terapeutisk strålebehandling af brystet, halsen eller aksillen; tidligere radioaktivt oralt jod er tilladt
- Ingen tidligere anamnese med ipsilateral brystkræft (invasiv sygdom eller duktalt brystcarcinom in situ [DCIS]); lobulært karcinom in situ (LCIS) og benign brystsygdom er tilladt
- Ingen historie med tidligere eller samtidig kontralateral invasiv brystkræft; godartet brystsygdom, LCIS eller DCIS af kontralateralt bryst er tilladt
- Ingen aktive kollagen vaskulære sygdomme, såsom: systemisk lupus erythematous, sklerodermi eller dermatomyositis
- Negative inked histologiske marginer fra mastektomipatologi (ingen invasive celler ved marginen). Patienter med DCIS ved margin er kvalificerede.
- Ingen signifikante komplikationer efter mastektomi i det ipsilaterale bryst, der kræver en uplanlagt genoperation eller indlæggelse for intravenøs (IV) antibiotika; genoperation til margenevaluering, nodalafslutning og rutinemæssig rekonstruktion er acceptabel
- Stråleonkolog har til hensigt at behandle alle målvolumener og respektere alle normale væv i overensstemmelse med de beskrevne dosimetriske begrænsninger (simulering før registrering anbefales)
- Stråleonkolog planlægger at behandle regionale lymfeknuder inklusive interne brystknuder og opfylde acceptable dosimetriske krav i protokol
- Stråleonkolog planlægger IKKE at bruge en brystvægs-/arboost
- Patienten skal have gennemgået øjeblikkelig rekonstruktion på tidspunktet for mastektomi eller planlægge at gennemgå rekonstruktion inden for 18 måneder efter stråling
- Behandlende læge og patient skal planlægge at starte strålebehandling inden for de tidsrammer, der er angivet i protokollen.
- Hvis en vævsekspander bruges, skal den være en væskefyldt ekspander, INGEN luftekspander (medmindre den er helt tømt for luft) under strålebehandling
- For patienter med diabetes skal hæmoglobin A1C-test være udført =< 90 dage før registrering
- Ingen samtidige medicinske tilstande med forventet levetid < 5 år
- Ingen anden malignitet inden for 5 år efter registrering med undtagelse af basalcelle- eller pladecellekarcinom i huden behandlet med lokal resektion alene eller carcinom in situ i livmoderhalsen
- Negativ graviditetstest (serum eller urin-HCG) hos kvinder i den fødedygtige alder ≤ 7 dage før registrering. Patienter, der har modtaget en bilateral tubal ligering, kræver stadig en negativ graviditetstest for at være berettiget. En kvinde i den fødedygtige alder er en kønsmoden kvinde, der ikke har gennemgået en hysterektomi eller bilateral ooforektomi og ikke har været naturligt postmenopausal i mindst 12 på hinanden følgende måneder
- Kvinder i den fødedygtige alder skal acceptere at bruge en form for prævention eller acceptere at gennemgå seksuel afholdenhed under strålebehandling
- Eastern Cooperative Oncology Group (ECOG) (Zubrod) præstationsstatus 0-1
- Patienter skal kunne læse og forstå engelsk for at kunne udfylde undersøgelsesspørgeskemaer; dog er patienter, der deltager gennem Canadian Cancer Trials Group (CCTG), som kan læse og forstå fransk, kvalificerede
Studieplan
Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.
Hvordan er undersøgelsen tilrettelagt?
Design detaljer
- Primært formål: Støttende pleje
- Tildeling: Randomiseret
- Interventionel model: Parallel tildeling
- Maskning: Ingen (Åben etiket)
Våben og indgreb
Deltagergruppe / Arm |
Intervention / Behandling |
|---|---|
|
Aktiv komparator: Gruppe I (strålebehandling)
Patienterne får dagligt strålebehandling mandag-fredag i 5-6 uger.
|
Korrelative undersøgelser
Hjælpestudier
Hjælpestudier
Gennemgå RT
|
|
Eksperimentel: Gruppe II (hypofraktioneret strålebehandling)
Patienterne gennemgår hypofraktioneret strålebehandling dagligt mandag-fredag i 3-4 uger.
|
Korrelative undersøgelser
Hjælpestudier
Hjælpestudier
Gennemgå hypofraktioneret RT
|
Hvad måler undersøgelsen?
Primære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
|---|---|---|
|
Andel af brystrekonstruktionskomplikationer
Tidsramme: 24 måneder
|
Det primære slutpunkt for denne undersøgelse er hyppigheden af komplikationer ved rekonstruktion af den ipsilaterale brystkirtel, defineret (i protokollen under 10.0. Måling af effekt) som; Kapselkontraktur (kun Baker grad III eller IV), fuldstændigt svigt af implantatet/hudlappen, uplanlagt indlæggelse på grund af rekonstruktionsrelaterede problemer, herunder men ikke begrænset til infektion, sårhelingskomplikation eller smerter, uplanlagt tilbagevenden til operationsstuen på grund af rekonstruktionsrelaterede problemer, herunder men ikke begrænset til infektion, proteseexponering, mislykket rekonstruktion, fjernelse af implantat, sårhelingskomplikationer eller behandling af kontraktur.
Bemærk: Rutinemæssige revisioner såsom hundørekorrektioner, fedttransplantation og revision af den kontralaterale brystkirtel registreres, men tælles ikke med i det primære slutpunkt; ii) Komplikationer relateret til den kontralaterale brystkirtel indsamles, men tælles ikke med i vurderingen af det primære slutpunkt, komplikationer ved den ipsilaterale brystkirtel tælles med i det primære slutpunkt.
|
24 måneder
|
Sekundære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
|---|---|---|
|
Forekomst af akutte og sene strålekomplikationer baseret på Common Terminology Criteria for Adverse Events 4.0-toksicitet
Tidsramme: 5 år
|
Andelen af patienter med akutte eller sene strålebehandlingskomplikationer vil blive estimeret separat for hver behandlingsarm og vil blive sammenlignet på tværs af de to arme ved hjælp af en to-udvalgs test af proportioner (Z-test) med en tosidet alternativ.
|
5 år
|
|
Lokal og lokalregional recidiv
Tidsramme: 3 år
|
Den kumulative forekomst af lokal og lokalregional recidiv vil blive estimeret separat for hver behandlingsgruppe ved hjælp af den kumulative incidensfunktion, hvor død behandles som en konkurrerende risiko, og vil blive sammenlignet ved hjælp af Gray's test.
|
3 år
|
|
Lokal og regional recidivfri overlevelse
Tidsramme: 3 år
|
Den lokale og lokale regionale recidivfri overlevelsesrate efter tre år vil blive opsummeret for hver arm ved hjælp af Kaplan-Meier estimaterne og vil blive sammenlignet ved hjælp af en log-rank test.
Ethvert recidiv eller dødsfald vil blive betragtet som en hændelse.
|
3 år
|
|
Rekonstruktionskomplikationsrater baseret på rekonstruktionsmetode (autolog +/- implantat versus [vs.] kun implantat) og tidspunkt for modtaget rekonstruktion (øjeblikkelig vs. hensigt om forsinket)
Tidsramme: Op til 5 år
|
Forskelle mellem behandlingsgrupper i komplikationsrater ved rekonstruktion vil blive vurderet separat inden for hver af de seks undergrupper baseret på type og timing af rekonstruktion.
Forskelle mellem behandlingsgrupper i komplikationsrater vil også blive vurderet inden for de to bredere undergrupper af patienter, der kun modtager implantat, og dem, der modtager autolog baseret rekonstruktion.
Inden for hver undergruppe vil sammenligningen blive udført ved hjælp af en to-prøve Z-test for proportioner med en to-sidet alternativ.
|
Op til 5 år
|
|
Rekonstruerede Bryst Fotografiske Kosmetiske Score
Tidsramme: Efter 24 måneder
|
Toårige fotografiske kosmetiske scores vil blive opsummeret efter behandlingsarm og vil blive sammenlignet på tværs af behandlingsarmene ved hjælp af en Wilcoxon rangsumtest med en tosidet alternativ.
Andelene af patienter med dårlig global kosmetisk score (defineret som en kosmetisk score på 3: dårlig eller stor forskel) 24 måneder efter stråling vil blive opsummeret separat efter behandlingsarm og vil blive sammenlignet ved hjælp af en toprøve test af andele med en tosidet alternativ.
|
Efter 24 måneder
|
|
Rekonstrueret Bryst Fotografiske Kosmetiske Scorer Baseret på Metoden og Tidspunktet for Modtaget Rekonstruktion
Tidsramme: Efter 24 måneder
|
To års fotografiske kosmetiske scorer og andelen af patienter med dårlig global kosmetisk score vil blive vurderet separat efter timing og rekonstruktionsmetode-undergrupper ved hjælp af en lignende metode som beskrevet ovenfor.
|
Efter 24 måneder
|
|
Forekomst af Armlympfødem Målt ved Procentvis Ændring i Ipsilateral Armvolumen Efter Bestråling Sammenlignet med Volumen Før Bestråling
Tidsramme: Op til 5 år
|
Andelen af patienter med armløfedem (defineret som en ændring på 10 % eller mere i ipsilateral armvolumen i forhold til volumen før stråleterapi) 2 år efter stråleterapi vil blive opsummeret og sammenlignet på tværs af de to behandlingsarme ved hjælp af en to-prøvers test for proportioner (Z-test) med en to-sidet alternativ.
Ændringer i ipsilateral armvolumen ved hver af følgende tidspunkter: 6, 12, 24 og 60 måneder efter stråleterapi (i forhold til før stråleterapi) vil blive sammenlignet ved hjælp af en to-prøvers t-test med en to-sidet alternativ.
Ændringerne i armvolumen ved disse tidspunkter vil også blive analyseret som en gentagen måling ved hjælp af en lineær blandet model med patient som den tilfældige effekt.
|
Op til 5 år
|
|
Fysisk trivsel, Psykosocial trivsel, Seksuel trivsel, Tilfredshed med bryster/nippels/mave og Tilfredshed med det samlede resultat
Tidsramme: Ved 24 måneder
|
Ændring i Lymphedema og Brystkræft Spørgeskema og Bryst Lymfødem-scorer ved 24 måneder efter strålebehandling (i forhold til før RT) og patienttilfredshedsscorer målt ved Bryst Spørgeskemaets overordnede resultatskala vil blive opsummeret og sammenlignet på tværs af behandlingsgrupperne ved hjælp af en to-prøvers t-test med en to-sidet alternativ.
Lineære blandede modeller vil også blive brugt til at vurdere disse scorer longitudinelt.
|
Ved 24 måneder
|
|
Patienttilfredshed med forsøgsdeltagelse efter behandlingsgruppe målt ved 'Var det det værd?'-spørgeskemaet
Tidsramme: Efter 24 måneder
|
Svar på spørgeskemaet 'Var det det værd?' for hvert af de fem spørgsmål ved 24 måneder vil blive sammenfattet og sammenlignet på tværs af behandlingsgrupper ved hjælp af et chi-i-anden-test med en tosidet alternativ.
|
Efter 24 måneder
|
|
Økonomiske Analyser
Tidsramme: Op til 5 år
|
De direkte omkostninger til medicinsk behandling for hver patient vil blive estimeret ved hjælp af udnyttelsesoplysninger fra sundhedsudgiftssurveyen og sundhedsudnyttelsessurveyen sammen med offentligt tilgængelige Medicare-refusionssatser.
Især baseret på det rapporterede antal ambulante besøg hos stråleonkologen, medicinsk onkolog, kirurg, der udførte mastektomi, plastikkirurg eller fysioterapeut, og antallet af besøg på skadestuen, antallet af hospitalsindlæggelser og antallet af kirurgiske indgreb til brystrekonstruktion, kan Medicare-refusionssatser bruges til at estimere, hvad den direkte omkostning for hver patient ville være, hvis patienten var dækket af Medicare.
Generalizede lineære modeller vil derefter blive brugt til at modellere disse omkostninger som en funktion af behandling, tid i studiet og alle tilgængelige baseline patientkarakteristika for at vurdere i hvilken grad estimerede direkte omkostninger påvirkes af typen af stråledosering.
|
Op til 5 år
|
Samarbejdspartnere og efterforskere
Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.
Efterforskere
- Studiestol: Matthew Poppe, MD, Huntsman Cancer Hospital, University of Utah
Datoer for undersøgelser
Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.
Studer store datoer
Studiestart (Faktiske)
12. marts 2018
Primær færdiggørelse (Faktiske)
1. februar 2024
Studieafslutning (Anslået)
1. august 2035
Datoer for studieregistrering
Først indsendt
17. januar 2018
Først indsendt, der opfyldte QC-kriterier
23. januar 2018
Først opslået (Faktiske)
30. januar 2018
Opdateringer af undersøgelsesjournaler
Sidste opdatering sendt (Faktiske)
24. februar 2026
Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier
5. februar 2026
Sidst verificeret
1. februar 2026
Mere information
Begreber relateret til denne undersøgelse
Yderligere relevante MeSH-vilkår
- Neoplasmer efter sted
- Neoplasmer
- Neoplasmer efter histologisk type
- Neoplasmer, kirtel og epitel
- Adenocarcinom
- Hudsygdomme
- Brystsygdomme
- Karcinom
- Neoplasmer, duktale, lobulære og medullære
- Carcinom, Ductal
- Hud- og bindevævssygdomme
- Brystneoplasmer
- Karcinom, duktal, bryst
- Karcinom, lobulær
- Terapeutik
- Strålebehandling
Andre undersøgelses-id-numre
- A221505
- NCI-2017-00817 (Registry Identifier: NCI Clinical Trial Reporting Program)
Lægemiddel- og udstyrsoplysninger, undersøgelsesdokumenter
Studerer et amerikansk FDA-reguleret lægemiddelprodukt
Ingen
Studerer et amerikansk FDA-reguleret enhedsprodukt
Ingen
produkt fremstillet i og eksporteret fra U.S.A.
Ingen
Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .
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Healthy.io Ltd.Afsluttet
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Modarres HospitalAfsluttetKomplikationer | Billedstyret biopsi | Nyre GlomerulusIran, Islamisk Republik