Forholdet mellem albumin/kreatin-forhold, B12, folat og skrøbelighedsindeks
Forholdet mellem albumin/kreatin-forhold, B12, folat og skrøbelighedsindeks hos patienter, der gennemgår mave-tarm-malignitetskirurgi
In the literature, the relationship between frailty and various blood tests such as beta-2 microglobulin, CRP, procalcitonin, vitamin D, IL-1, and IL-6 has been investigated (2). In our study, the investigators aim to investigate the relationship between frailty status assessed using frailty scale forms (Frailty Scale Version 9) and preoperative levels of Albumin/Creatinine, B12, Folate, Ferritin, hemogram, Sedimentation Rate, and CRP in patients undergoing gastrointestinal malignancy surgery. By identifying the relationship among these parameters, the investigators believe that modifiable factors contributing to frailty in patients at risk can be addressed through appropriate interventions.
Studieoversigt
Status
Betingelser
Intervention / Behandling
Detaljeret beskrivelse
Frailty is a condition associated with a decline in physiological performance. Patients are categorized as healthy, pre-frail, or frail based on physiological and functional characteristics. Frailty is known to be influenced by various lifestyle factors such as socioeconomic status, psychological factors, diet, exercise, and genetic predisposition. With aging, there is an increase in cognitive and physical dysfunction, which correlates with an increase in frailty. Along with frailty, geriatric symptoms, mortality, and other negative health outcomes also increase in the elderly population. Therefore, early detection of frailty is crucial to implementing lifestyle changes aimed at improving cognitive and physical status. Various assessment scales are used to evaluate frailty, such as the Frailty Scale Version 9.
In the literature, the relationship between frailty and various blood tests such as beta-2 microglobulin, CRP, procalcitonin, vitamin D, IL-1, and IL-6 has been investigated (2). In our study, the investigators aim to investigate the relationship between frailty status assessed using frailty scale form (Frailty Scale Version 9) and preoperative levels of Albumin/Creatinine, B12, Folate, Ferritin,hemogram, Sedimentation Rate, and CRP in patients undergoing gastrointestinal malignancy surgery. By identifying the relationship among these parameters, the investigators believe that modifiable factors contributing to frailty in patients at risk can be addressed through appropriate interventions.
Undersøgelsestype
Tilmelding (Anslået)
Kontakter og lokationer
Studiekontakt
- Navn: Yusuf Ozguner
- Telefonnummer: 05427150725
- E-mail: y.ozguner@hotmail.com
Studiesteder
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Ankara
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Çankaya, Ankara, Tyrkiet (Türkiye)
- Rekruttering
- Yusuf
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Kontakt:
- Yusuf Ozguner
- Telefonnummer: 05427150725
- E-mail: y.ozguner@hotmail.com
-
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Varlık Mahallesi, Halil Sezai Erkut Caddesi Yenimahalle
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Ankara, Varlık Mahallesi, Halil Sezai Erkut Caddesi Yenimahalle, Tyrkiet (Türkiye), 06170
- Rekruttering
- Ankara Etlik City Hospital
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Kontakt:
- Yusuf Ozguner
- Telefonnummer: +903127970000
- E-mail: etliksh.iletisim@saglik.gov.tr
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Deltagelseskriterier
Berettigelseskriterier
Aldre berettiget til at studere
Tager imod sunde frivillige
Køn, der er berettiget til at studere
Prøveudtagningsmetode
Studiebefolkning
In our study, we aim to investigate the relationship between frailty status assessed using frailty scale form (Frailty Scale Version 9) and preoperative levels of Albumin/Creatine, B12, Folate, Ferritin, Sedimentation Rate, and CRP in patients undergoing gastrointestinal malignancy surgery.
Beskrivelse
Inclusion Criteria:
- Patients who are over 65 years old.
- Patients classified under ASA (American Society of Anesthesiologists) risk groups I, II, and III.
- Patients with gastrointestinal malignancy undergoing surgery
Exclusion Criteria:
- Patients who are under 65 years old.
- Patients with an ASA score of IV or higher.
- Patients who refuse to participate in the study.
- Patients undergoing emergency surgeries will be excluded from the study
Studieplan
Hvordan er undersøgelsen tilrettelagt?
Design detaljer
- Observationsmodeller: CASE_ONLY
- Tidsperspektiver: PROSPECTIVE
Kohorter og interventioner
Gruppe / kohorte |
Intervention / Behandling |
|---|---|
|
Undergoing gastrointestinal malignancy surgery
In our study, we aim to investigate the relationship between frailty status assessed using frailty scale form (Frailty Scale Version 9) and preoperative levels of Albumin/Creatinine, B12, Folate, Hemogram in patients undergoing gastrointestinal malignancy surgery.Patients' frailty status will be assessed using the Frailty Scale Version 9.There are scores between 1 and 9 on this scale. Patients with a score of 4 or above are defined as fraile. |
In our study, we aim to investigate the relationship between frailty status assessed using frailty scale form (Frailty Scale Version 9) and preoperative levels of Albumin/Creatinine, B12, Folate, Ferritin, Sedimentation Rate, and CRP in patients undergoing gastrointestinal malignancy surgery. |
Hvad måler undersøgelsen?
Primære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
|---|---|---|
|
Association between preoperative Clinical Frailty Scale (CFS) score and serum albumin-to-creatinine ratio
Tidsramme: one day before surgery
|
Patients' frailty status will be assessed using the Frailty Scale Version 9.There are scores between 1 and 9 on this scale. Patients with a score of 4 or above are defined as fraile.(Association between preoperative Clinical Frailty Scale (CFS) score and serum albumin-to-creatinine ratio.) |
one day before surgery
|
Sekundære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
|---|---|---|
|
Association between preoperative Clinical Frailty Scale (CFS) score and B12 levels
Tidsramme: one day before surgery
|
B12 concentration will be measured |
one day before surgery
|
|
Association between preoperative Clinical Frailty Scale (CFS) score and Folate levels
Tidsramme: one day before surgery
|
Folate concentration will be measured |
one day before surgery
|
|
Association between preoperative Clinical Frailty Scale (CFS) score and iron levels
Tidsramme: one day before surgery
|
Serum iron concentration will be measured. |
one day before surgery
|
|
Association between preoperative Clinical Frailty Scale (CFS) score and Hemoglobin/RDW ratio.
Tidsramme: one day before surgery
|
Hemoglobin/RDW ratio will be measured. |
one day before surgery
|
Samarbejdspartnere og efterforskere
Sponsor
Efterforskere
- Ledende efterforsker: Yusuf Ozguner, Ankara Etlik City Hospital
Publikationer og nyttige links
Generelle publikationer
- Kim M, Suzuki T, Kojima N, Yoshida H, Yoshida Y, Hirano H, Won CW, Kim H. Association Between Serum beta2 -Microglobulin Levels and Prevalent and Incident Physical Frailty in Community-Dwelling Older Women. J Am Geriatr Soc. 2017 Apr;65(4):e83-e88. doi: 10.1111/jgs.14733. Epub 2017 Jan 31.
- Shamliyan T, Talley KM, Ramakrishnan R, Kane RL. Association of frailty with survival: a systematic literature review. Ageing Res Rev. 2013 Mar;12(2):719-36. doi: 10.1016/j.arr.2012.03.001. Epub 2012 Mar 12.
Datoer for undersøgelser
Studer store datoer
Studiestart (Faktiske)
Primær færdiggørelse (Anslået)
Studieafslutning (Anslået)
Datoer for studieregistrering
Først indsendt
Først indsendt, der opfyldte QC-kriterier
Først opslået (Faktiske)
Opdateringer af undersøgelsesjournaler
Sidste opdatering sendt (Faktiske)
Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier
Sidst verificeret
Mere information
Begreber relateret til denne undersøgelse
Yderligere relevante MeSH-vilkår
Andre undersøgelses-id-numre
- AnkaraEtlikYusufOzguner007
Lægemiddel- og udstyrsoplysninger, undersøgelsesdokumenter
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