The First 1,000 Days Program: Maternal-Child Obesity Prevention in Early Life
The First 1000 Days (conception to age 2) is a crucial period for the development and prevention of obesity and its adverse consequences in mother-child pairs and their families. The overall aim of the First 1000 Days program is to work across early-life systems to prevent obesity, promote healthy routines and behaviors, address social determinants of health, and reduce health disparities among vulnerable children and families at community health centers in the Boston, MA area.
The study aims to simultaneously implement and evaluate an obesity prevention program across early life systems to reduce the prevalence of obesity risk factors within racial/ethnic minority families, close the gap in maternal-child health disparities, and assess and address social determinants of health.
調査の概要
研究の種類
入学 (予想される)
段階
- 適用できない
参加基準
適格基準
就学可能な年齢
- 子
- 大人
- 高齢者
健康ボランティアの受け入れ
受講資格のある性別
説明
Inclusion Criteria:
- All pregnant women receiving prenatal care at select community health centers in the Boston, MA area
- All families of children aged 0-2 years receiving pediatric care at select community health centers in the Boston, MA area
研究計画
研究はどのように設計されていますか?
デザインの詳細
- 主な目的:防止
- 割り当て:なし
- 介入モデル:単一グループの割り当て
- マスキング:なし(オープンラベル)
武器と介入
参加者グループ / アーム |
介入・治療 |
---|---|
実験的:First 1,000 Days Program
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Program components will include 1) Enhancements to and improved use of electronic health records to improve the quality of preventive services and screening for social determinants of health; 2) Staff and provider training; 3) Consistent behavior change messaging; 4) Patient education via print materials, text messaging and short videos; and 5) Strengthening the integration of clinical and public health services to support behavior change and address social determinants of health.
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この研究は何を測定していますか?
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
---|---|---|
Maternal Gestational Weight Gain
時間枠:First prenatal care visit to 36 weeks gestation
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Weight gained during pregnancy
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First prenatal care visit to 36 weeks gestation
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Infant Weight-for-Length Z-Score
時間枠:Child age 6 months
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Age- and sex-specific weight-for-length z-score
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Child age 6 months
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Infant Weight-for-Length Z-score
時間枠:Child age 12 months
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Age- and sex-specific weight-for-length z-score
|
Child age 12 months
|
Infant Weight-for-Length Z-Score
時間枠:Child age 24 months
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Age- and sex-specific weight-for-length z-score
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Child age 24 months
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二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
---|---|---|
Change from 1st trimester maternal diet to 3rd trimester
時間枠:An average of 18 weeks (1st trimester to 3rd trimester)
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Average weekly intake
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An average of 18 weeks (1st trimester to 3rd trimester)
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Change from 1st trimester maternal physical activity to 3rd trimester
時間枠:An average of 18 weeks (1st trimester to 3rd trimester)
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Days per week physically active for at least 30 minutes per day
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An average of 18 weeks (1st trimester to 3rd trimester)
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Change from 1st trimester maternal sleep duration to 3rd trimester
時間枠:An average of 18 weeks (1st trimester to 3rd trimester)
|
Average hours per day
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An average of 18 weeks (1st trimester to 3rd trimester)
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Change from 1st trimester maternal sedentary time to 3rd trimester
時間枠:An average of 18 weeks (1st trimester to 3rd trimester)
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Hours per day of screentime
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An average of 18 weeks (1st trimester to 3rd trimester)
|
Change from 1st trimester depression to 3rd trimester
時間枠:An average of 18 weeks (1st trimester to 3rd trimester)
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Edinburgh Postnatal Depression Scale
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An average of 18 weeks (1st trimester to 3rd trimester)
|
Change from 1st trimester maternal food insecurity to 3rd trimester
時間枠:An average of 18 weeks (1st trimester to 3rd trimester)
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2-question validated scale
|
An average of 18 weeks (1st trimester to 3rd trimester)
|
Change from 1st trimester maternal housing insecurity to 3rd trimester
時間枠:An average of 18 weeks (1st trimester to 3rd trimester)
|
2-question validated scale
|
An average of 18 weeks (1st trimester to 3rd trimester)
|
Change from 1st trimester pregnancy-related anxiety to 3rd trimester
時間枠:An average of 18 weeks (1st trimester to 3rd trimester)
|
5-question validated scale
|
An average of 18 weeks (1st trimester to 3rd trimester)
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Change from 1st trimester enrollment in food assistance programs to 3rd trimester
時間枠:An average of 18 weeks (1st trimester to 3rd trimester)
|
Yes/No response options for program enrollment in WIC and SNAP
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An average of 18 weeks (1st trimester to 3rd trimester)
|
協力者と研究者
出版物と役立つリンク
一般刊行物
- Blake-Lamb T, Boudreau AA, Matathia S, Perkins ME, Roche B, Cheng ER, Kotelchuck M, Shtasel D, Taveras EM. Association of the First 1,000 Days Systems-Change Intervention on Maternal Gestational Weight Gain. Obstet Gynecol. 2020 May;135(5):1047-1057. doi: 10.1097/AOG.0000000000003752.
- Simione M, Moreno-Galarraga L, Perkins M, Price SN, Luo M, Kotelchuck M, Blake-Lamb TL, Taveras EM. Effects of the First 1000 Days Program, a systems-change intervention, on obesity risk factors during pregnancy. BMC Pregnancy Childbirth. 2021 Oct 27;21(1):729. doi: 10.1186/s12884-021-04210-9.
- Taveras EM, Perkins ME, Boudreau AA, Blake-Lamb T, Matathia S, Kotelchuck M, Luo M, Price SN, Roche B, Cheng ER. Twelve-Month Outcomes of the First 1000 Days Program on Infant Weight Status. Pediatrics. 2021 Aug;148(2). pii: e2020046706. doi: 10.1542/peds.2020-046706.
- Cruz-Bendezu AM, Lovell GV, Roche B, Perkins M, Blake-Lamb TL, Taveras EM, Simione M. Psychosocial status and prenatal care of unintended pregnancies among low-income women. BMC Pregnancy Childbirth. 2020 Oct 12;20(1):615. doi: 10.1186/s12884-020-03302-2.
- Blake-Lamb T, Boudreau AA, Matathia S, Tiburcio E, Perkins ME, Roche B, Kotelchuck M, Shtasel D, Price SN, Taveras EM. Strengthening integration of clinical and public health systems to prevent maternal-child obesity in the First 1,000Days: A Collective Impact approach. Contemp Clin Trials. 2018 Feb;65:46-52. doi: 10.1016/j.cct.2017.12.001. Epub 2017 Dec 7.
研究記録日
主要日程の研究
研究開始 (実際)
一次修了 (実際)
研究の完了 (実際)
試験登録日
最初に提出
QC基準を満たした最初の提出物
最初の投稿 (実際)
学習記録の更新
投稿された最後の更新 (実際)
QC基準を満たした最後の更新が送信されました
最終確認日
詳しくは
本研究に関する用語
キーワード
その他の研究ID番号
- 2016P000801
- 1K24DK105989 (米国 NIH グラント/契約)
個々の参加者データ (IPD) の計画
個々の参加者データ (IPD) を共有する予定はありますか?
医薬品およびデバイス情報、研究文書
米国FDA規制医薬品の研究
米国FDA規制機器製品の研究
米国で製造され、米国から輸出された製品。
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