Evaluation of the Effects of Oxygen Therapy and Enalapril for Diabetic Macular Ischemia
In this study, patients were divided into 3 group with 35 cases including: 1.oxygen 2.enalapril 3.control.
In the beginning of the study, best corrected visual acuity (BCVA), uncorrected visual acuity (UCVA), and optical coherence tomography (OCT) were measured. Patients in the oxygen group were given oxygen 10 lit/min 1 hour twice a day at the first month, once a day at the second month and every other day at the third month. In the enalapril group, patients were given enalapril 5 mg every night and placebo was given for the patients in third group. At the end of first month the patients' vision was checked again and at the the end of the third month the first physical examinations were performed. In the first group, arterial blood gas (ABG) was taken before and after oxygen therapy as well.
研究概览
研究类型
阶段
- 阶段1
联系人和位置
学习联系方式
- 姓名:Masoud Soheilian, MD
- 电话号码:+982122585952
- 邮箱:labbafi@hotmail.com
学习地点
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Tehran、伊朗伊斯兰共和国、166666
- 招聘中
- Ophthalmic Research Center
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接触:
- Masoud Soheilian, MD
- 电话号码:+98 21 22585952
- 邮箱:labbafi@hotmail.com
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参与标准
资格标准
适合学习的年龄
- 孩子
- 成人
- 年长者
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- Patients diagnosed with diabetic macular ischemia
Exclusion Criteria:
- HTN > 1140/90 or HTN controlled by ACE inhibitors
- FBS > 200
- Severe anemia, COPD, cataract, HRPDR and diffuse macular edema
学习计划
研究是如何设计的?
武器和干预
参与者组/臂 |
干预/治疗 |
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安慰剂比较:控制
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实验性的:依那普利
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enalapril 5 mg every night
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实验性的:氧
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oxygen 10 lit/min 1 hour twice a day at the first month, once a day at the second month and every other day at the third month
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合作者和调查者
研究记录日期
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
此信息直接从 clinicaltrials.gov 网站检索,没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求,请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改,我们的网站上也会自动更新.
安慰剂的临床试验
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Mila (bMotion Technologies)完全的
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Universidad Autonoma de MadridCentro Universitario La Salle完全的